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• W3207670128 abstract "The production of 18F-labelled microbubbles (MBs) via the aluminium-[18F]fluoride ([18F]AlF) radiolabelling method and facile inverse-electron-demand Diels-Alder (IEDDA) 'click' chemistry is reported. An [18F]AlF-NODA-labelled tetrazine was synthesised in excellent radiochemical yield (>95% RCY) and efficiently conjugated to a trans-cyclooctene (TCO) functionalised phospholipid (40-50% RCY), which was incorporated into MBs (40-50% RCY). To demonstrate the potential of producing 18F-labelled MBs for clinical studies, we also describe a kit-based approach which is amenable for use in a hospital radiopharmacy setting." @default.
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• W3207670128 date "2021-01-01" @default.
• W3207670128 modified "2023-10-12" @default.
• W3207670128 title "A kit-based aluminium-[¹⁸F]fluoride approach to radiolabelled microbubbles" @default.
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• W3207670128 doi "https://doi.org/10.1039/d1cc04790f" @default.
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