Matches in SemOpenAlex for { <https://semopenalex.org/work/W3207884039> ?p ?o ?g. }
- W3207884039 endingPage "397" @default.
- W3207884039 startingPage "387" @default.
- W3207884039 abstract "Abstract Background Inositol is a sugar‐alcohol and recognized as a key component of cell membrane phospholipids. It has crucial role in the cell signaling pathways and contribute to improving glycemic responses. Although some earlier studies have revealed the effect of inositol mediating glucose uptake by improving insulin sensitivity, the benefit of inositol supplementation in patients with overweight and obesity is not completely understood. This study aimed to assess the impact of inositol supplementation on body mass index (BMI) through a systematic review and meta‐analysis of controlled clinical trials. Methods A systematic search was performed to August 2021 in the following databases: PubMed‐Medline, Embase, Web of Science and Scopus. Fifteen controlled clinical trials investigating the effect of inositol on adult's BMI were finally included in the study. A random‐effects model was employed to estimate the effect size. Subgroup analysis was performed by dose, duration, age, type of inositol. Meta‐regression was used to investigate presence of any linear relationship. Begg's and Egger's tests were carried out to detect small study effect. Results The results of pooled analysis showed that inositol supplementation significantly decreased BMI scores (WMD = −0.41 kg/m 2 ; 95% CI: −0.78, −0.04; p = 0.028). Subgroup analysis was performed to identify the source of heterogeneity among studies ( I 2 = 73.9%, p < 0.001), demonstrating supplementation duration, baseline BMI, mean age of participants, type of inositol and dosage were potential sources of heterogeneity. The effect of intervention was more clinically significant in participants with polycystic ovary syndrome (PCOS) and overweight/obesity. Inositol in the form of myo‐inositol (MI) had stronger effect on BMI reduction. Conclusion The meta‐analysis suggests that oral inositol supplementation has positive effect on BMI reduction. Inositol supplementation could be considered as an adjunct treatment to improve body mass index." @default.
- W3207884039 created "2021-10-25" @default.
- W3207884039 creator A5011825950 @default.
- W3207884039 creator A5018105299 @default.
- W3207884039 creator A5018802018 @default.
- W3207884039 creator A5021675199 @default.
- W3207884039 creator A5054314403 @default.
- W3207884039 creator A5058984399 @default.
- W3207884039 creator A5061047808 @default.
- W3207884039 creator A5065572850 @default.
- W3207884039 creator A5078974365 @default.
- W3207884039 creator A5079262149 @default.
- W3207884039 date "2021-10-22" @default.
- W3207884039 modified "2023-09-26" @default.
- W3207884039 title "Inositol supplementation and body mass index: A systematic review and meta‐analysis of randomized clinical trials" @default.
- W3207884039 cites W1441547069 @default.
- W3207884039 cites W1563215675 @default.
- W3207884039 cites W1964435302 @default.
- W3207884039 cites W1967030744 @default.
- W3207884039 cites W1972948495 @default.
- W3207884039 cites W1976448511 @default.
- W3207884039 cites W1979423827 @default.
- W3207884039 cites W1982488301 @default.
- W3207884039 cites W1984371946 @default.
- W3207884039 cites W2003681692 @default.
- W3207884039 cites W2012168904 @default.
- W3207884039 cites W2030758262 @default.
- W3207884039 cites W2034664451 @default.
- W3207884039 cites W2038874580 @default.
- W3207884039 cites W2039057302 @default.
- W3207884039 cites W2041706856 @default.
- W3207884039 cites W2045643588 @default.
- W3207884039 cites W2056107937 @default.
- W3207884039 cites W2070119291 @default.
- W3207884039 cites W2086082646 @default.
- W3207884039 cites W2086557309 @default.
- W3207884039 cites W2090555668 @default.
- W3207884039 cites W2095365589 @default.
- W3207884039 cites W2096793224 @default.
- W3207884039 cites W2109290246 @default.
- W3207884039 cites W2118255202 @default.
- W3207884039 cites W2123074232 @default.
- W3207884039 cites W2127991037 @default.
- W3207884039 cites W2132693290 @default.
- W3207884039 cites W2135069653 @default.
- W3207884039 cites W2135328187 @default.
- W3207884039 cites W2153439837 @default.
- W3207884039 cites W2157823046 @default.
- W3207884039 cites W2171177397 @default.
- W3207884039 cites W2203698522 @default.
- W3207884039 cites W2326657859 @default.
- W3207884039 cites W2414963813 @default.
- W3207884039 cites W2509769179 @default.
- W3207884039 cites W2512910707 @default.
- W3207884039 cites W2517305958 @default.
- W3207884039 cites W2532389572 @default.
- W3207884039 cites W2565379600 @default.
- W3207884039 cites W2567362164 @default.
- W3207884039 cites W2588681363 @default.
- W3207884039 cites W2607125527 @default.
- W3207884039 cites W2766692637 @default.
- W3207884039 cites W2767038233 @default.
- W3207884039 cites W2805456604 @default.
- W3207884039 cites W2901913741 @default.
- W3207884039 cites W2908602350 @default.
- W3207884039 cites W2925118343 @default.
- W3207884039 cites W2958586517 @default.
- W3207884039 cites W2978795816 @default.
- W3207884039 cites W2994918891 @default.
- W3207884039 cites W316023088 @default.
- W3207884039 cites W3207884039 @default.
- W3207884039 doi "https://doi.org/10.1002/osp4.569" @default.
- W3207884039 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/35664247" @default.
- W3207884039 hasPublicationYear "2021" @default.
- W3207884039 type Work @default.
- W3207884039 sameAs 3207884039 @default.
- W3207884039 citedByCount "6" @default.
- W3207884039 countsByYear W32078840392021 @default.
- W3207884039 countsByYear W32078840392023 @default.
- W3207884039 crossrefType "journal-article" @default.
- W3207884039 hasAuthorship W3207884039A5011825950 @default.
- W3207884039 hasAuthorship W3207884039A5018105299 @default.
- W3207884039 hasAuthorship W3207884039A5018802018 @default.
- W3207884039 hasAuthorship W3207884039A5021675199 @default.
- W3207884039 hasAuthorship W3207884039A5054314403 @default.
- W3207884039 hasAuthorship W3207884039A5058984399 @default.
- W3207884039 hasAuthorship W3207884039A5061047808 @default.
- W3207884039 hasAuthorship W3207884039A5065572850 @default.
- W3207884039 hasAuthorship W3207884039A5078974365 @default.
- W3207884039 hasAuthorship W3207884039A5079262149 @default.
- W3207884039 hasBestOaLocation W32078840391 @default.
- W3207884039 hasConcept C126322002 @default.
- W3207884039 hasConcept C168563851 @default.
- W3207884039 hasConcept C170493617 @default.
- W3207884039 hasConcept C187960798 @default.
- W3207884039 hasConcept C2777427919 @default.
- W3207884039 hasConcept C2779473830 @default.
- W3207884039 hasConcept C2780221984 @default.