Matches in SemOpenAlex for { <https://semopenalex.org/work/W3207895384> ?p ?o ?g. }
- W3207895384 abstract "Abstract Brain function relies on efficient communications between distinct brain systems. The pathology of major depressive disorder (MDD) damages functional brain networks, resulting in cognitive impairment. Here, we reviewed the associations between brain functional connectome changes and MDD pathogenesis. We also highlighted the utility of brain functional connectome for differentiating MDD from other similar psychiatric disorders, predicting recurrence and suicide attempts in MDD, and evaluating treatment responses. Converging evidence has now linked aberrant brain functional network organization in MDD to the dysregulation of neurotransmitter signaling and neuroplasticity, providing insights into the neurobiological mechanisms of the disease and antidepressant efficacy. Widespread connectome dysfunctions in MDD patients include multiple, large-scale brain networks as well as local disturbances in brain circuits associated with negative and positive valence systems and cognitive functions. Although the clinical utility of the brain functional connectome remains to be realized, recent findings provide further promise that research in this area may lead to improved diagnosis, treatments, and clinical outcomes of MDD." @default.
- W3207895384 created "2021-10-25" @default.
- W3207895384 creator A5007656986 @default.
- W3207895384 creator A5021143872 @default.
- W3207895384 creator A5023168022 @default.
- W3207895384 creator A5029722430 @default.
- W3207895384 creator A5033842129 @default.
- W3207895384 creator A5042823956 @default.
- W3207895384 creator A5076556927 @default.
- W3207895384 creator A5079594267 @default.
- W3207895384 creator A5082789515 @default.
- W3207895384 creator A5086519506 @default.
- W3207895384 date "2021-10-13" @default.
- W3207895384 modified "2023-10-18" @default.
- W3207895384 title "Understanding complex functional wiring patterns in major depressive disorder through brain functional connectome" @default.
- W3207895384 cites W1162221644 @default.
- W3207895384 cites W1696318955 @default.
- W3207895384 cites W1757520340 @default.
- W3207895384 cites W1822737135 @default.
- W3207895384 cites W1960878161 @default.
- W3207895384 cites W1964212874 @default.
- W3207895384 cites W1975310269 @default.
- W3207895384 cites W1980841278 @default.
- W3207895384 cites W1982931669 @default.
- W3207895384 cites W1988972283 @default.
- W3207895384 cites W1999919402 @default.
- W3207895384 cites W2004826931 @default.
- W3207895384 cites W2004920788 @default.
- W3207895384 cites W2006931708 @default.
- W3207895384 cites W2016343597 @default.
- W3207895384 cites W2037316926 @default.
- W3207895384 cites W2040344668 @default.
- W3207895384 cites W2050618347 @default.
- W3207895384 cites W2064589328 @default.
- W3207895384 cites W2066916484 @default.
- W3207895384 cites W2095438393 @default.
- W3207895384 cites W2095651675 @default.
- W3207895384 cites W2098547840 @default.
- W3207895384 cites W2100260106 @default.
- W3207895384 cites W2107196007 @default.
- W3207895384 cites W2108891761 @default.
- W3207895384 cites W2109359002 @default.
- W3207895384 cites W2123011980 @default.
- W3207895384 cites W2131398580 @default.
- W3207895384 cites W2137113819 @default.
- W3207895384 cites W2140164239 @default.
- W3207895384 cites W2142106331 @default.
- W3207895384 cites W2151056016 @default.
- W3207895384 cites W2152850599 @default.
- W3207895384 cites W2155756488 @default.
- W3207895384 cites W2155855194 @default.
- W3207895384 cites W2170891230 @default.
- W3207895384 cites W2173893173 @default.
- W3207895384 cites W2289181816 @default.
- W3207895384 cites W2344320993 @default.
- W3207895384 cites W2463384901 @default.
- W3207895384 cites W2485471030 @default.
- W3207895384 cites W2507387536 @default.
- W3207895384 cites W2519531315 @default.
- W3207895384 cites W2520169676 @default.
- W3207895384 cites W2531210989 @default.
- W3207895384 cites W2551253757 @default.
- W3207895384 cites W2552589017 @default.
- W3207895384 cites W2553251493 @default.
- W3207895384 cites W2554626917 @default.
- W3207895384 cites W2580270456 @default.
- W3207895384 cites W2587272693 @default.
- W3207895384 cites W2587296514 @default.
- W3207895384 cites W2590906340 @default.
- W3207895384 cites W2597061250 @default.
- W3207895384 cites W2600089334 @default.
- W3207895384 cites W2601063088 @default.
- W3207895384 cites W2601883067 @default.
- W3207895384 cites W2603870485 @default.
- W3207895384 cites W2604911769 @default.
- W3207895384 cites W2607109883 @default.
- W3207895384 cites W2621453941 @default.
- W3207895384 cites W2623836892 @default.
- W3207895384 cites W2733689132 @default.
- W3207895384 cites W2734822428 @default.
- W3207895384 cites W2758974767 @default.
- W3207895384 cites W2774368682 @default.
- W3207895384 cites W2775562803 @default.
- W3207895384 cites W2779859049 @default.
- W3207895384 cites W2784118244 @default.
- W3207895384 cites W2790639783 @default.
- W3207895384 cites W2793884052 @default.
- W3207895384 cites W2803140159 @default.
- W3207895384 cites W2804588921 @default.
- W3207895384 cites W2810237733 @default.
- W3207895384 cites W2884529364 @default.
- W3207895384 cites W2884750718 @default.
- W3207895384 cites W2890225331 @default.
- W3207895384 cites W2892392001 @default.
- W3207895384 cites W2893924648 @default.
- W3207895384 cites W2894700234 @default.
- W3207895384 cites W2896787097 @default.
- W3207895384 cites W2901578484 @default.
- W3207895384 cites W2902403458 @default.
- W3207895384 cites W2904629699 @default.