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- W3207949416 endingPage "11197" @default.
- W3207949416 startingPage "11197" @default.
- W3207949416 abstract "Glioma is the most common and aggressive tumor of the central nervous system. The uncontrolled proliferation, cellular heterogeneity, and diffusive capacity of glioma cells contribute to a very poor prognosis of patients with high grade glioma. Compared to normal cells, cancer cells exhibit a higher rate of glucose uptake, which is accompanied with the metabolic switch from oxidative phosphorylation to aerobic glycolysis. The metabolic reprogramming of cancer cell supports excessive cell proliferation, which are frequently mediated by the activation of oncogenes or the perturbations of tumor suppressor genes. Recently, a growing body of evidence has started to reveal that long noncoding RNAs (lncRNAs) are implicated in a wide spectrum of biological processes in glioma, including malignant phenotypes and aerobic glycolysis. However, the mechanisms of diverse lncRNAs in the initiation and progression of gliomas remain to be fully unveiled. In this review, we summarized the diverse roles of lncRNAs in shaping the biological features and aerobic glycolysis of glioma. The thorough understanding of lncRNAs in glioma biology provides opportunities for developing diagnostic biomarkers and novel therapeutic strategies targeting gliomas." @default.
- W3207949416 created "2021-10-25" @default.
- W3207949416 creator A5013412405 @default.
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- W3207949416 creator A5056248574 @default.
- W3207949416 creator A5069760097 @default.
- W3207949416 creator A5079513967 @default.
- W3207949416 date "2021-10-18" @default.
- W3207949416 modified "2023-10-18" @default.
- W3207949416 title "Mechanisms of Long Non-Coding RNAs in Biological Characteristics and Aerobic Glycolysis of Glioma" @default.
- W3207949416 cites W1490655572 @default.
- W3207949416 cites W1935974026 @default.
- W3207949416 cites W1964113455 @default.
- W3207949416 cites W1964497386 @default.
- W3207949416 cites W2009244520 @default.
- W3207949416 cites W2012935431 @default.
- W3207949416 cites W2026198465 @default.
- W3207949416 cites W2028308239 @default.
- W3207949416 cites W2029627701 @default.
- W3207949416 cites W2044958267 @default.
- W3207949416 cites W2060551076 @default.
- W3207949416 cites W2062502437 @default.
- W3207949416 cites W206348675 @default.
- W3207949416 cites W2097259163 @default.
- W3207949416 cites W2104287126 @default.
- W3207949416 cites W2110619464 @default.
- W3207949416 cites W2129375421 @default.
- W3207949416 cites W2153268494 @default.
- W3207949416 cites W2160315579 @default.
- W3207949416 cites W2179712880 @default.
- W3207949416 cites W2184957080 @default.
- W3207949416 cites W2260922547 @default.
- W3207949416 cites W2282529067 @default.
- W3207949416 cites W2339414115 @default.
- W3207949416 cites W2392045628 @default.
- W3207949416 cites W2396581103 @default.
- W3207949416 cites W2408928001 @default.
- W3207949416 cites W2526615614 @default.
- W3207949416 cites W2538639834 @default.
- W3207949416 cites W2550284103 @default.
- W3207949416 cites W2558404077 @default.
- W3207949416 cites W2558842054 @default.
- W3207949416 cites W2562182278 @default.
- W3207949416 cites W2564360633 @default.
- W3207949416 cites W2585659713 @default.
- W3207949416 cites W2607640564 @default.
- W3207949416 cites W2623629471 @default.
- W3207949416 cites W2659689178 @default.
- W3207949416 cites W2724280890 @default.
- W3207949416 cites W2735934509 @default.
- W3207949416 cites W2737004789 @default.
- W3207949416 cites W2738647095 @default.
- W3207949416 cites W2759858864 @default.
- W3207949416 cites W2769373441 @default.
- W3207949416 cites W2770894379 @default.
- W3207949416 cites W2774855547 @default.
- W3207949416 cites W2782521778 @default.
- W3207949416 cites W2786569819 @default.
- W3207949416 cites W2787895823 @default.
- W3207949416 cites W2789326851 @default.
- W3207949416 cites W2792979573 @default.
- W3207949416 cites W2796324480 @default.
- W3207949416 cites W2800469107 @default.
- W3207949416 cites W2803499181 @default.
- W3207949416 cites W2807003152 @default.
- W3207949416 cites W2809263068 @default.
- W3207949416 cites W2892307311 @default.
- W3207949416 cites W2898161455 @default.
- W3207949416 cites W2902831422 @default.
- W3207949416 cites W2904672337 @default.
- W3207949416 cites W2905017500 @default.
- W3207949416 cites W2908747018 @default.
- W3207949416 cites W2914805278 @default.
- W3207949416 cites W2920277785 @default.
- W3207949416 cites W2926902798 @default.
- W3207949416 cites W2928159322 @default.
- W3207949416 cites W2950187230 @default.
- W3207949416 cites W2950278520 @default.
- W3207949416 cites W2951118697 @default.
- W3207949416 cites W2953192053 @default.
- W3207949416 cites W2954220199 @default.
- W3207949416 cites W2956284778 @default.
- W3207949416 cites W2962533769 @default.
- W3207949416 cites W2967722537 @default.
- W3207949416 cites W2970214159 @default.
- W3207949416 cites W2970387618 @default.
- W3207949416 cites W2971126595 @default.
- W3207949416 cites W2981519666 @default.
- W3207949416 cites W2988901166 @default.
- W3207949416 cites W2990301349 @default.
- W3207949416 cites W2994405351 @default.
- W3207949416 cites W2996448448 @default.
- W3207949416 cites W2997406734 @default.
- W3207949416 cites W3006119786 @default.
- W3207949416 cites W3008008711 @default.
- W3207949416 cites W3008568758 @default.
- W3207949416 cites W3009687707 @default.
- W3207949416 cites W3009898868 @default.