FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W3208022770> ?p ?o ?g. }

• W3208022770 abstract "Abstract Large-scale computational models of the brain are necessary to accurately represent anatomical and functional variability in neuronal biophysics across brain regions and also to capture and study local and global interactions between neuronal populations on a behaviorally-relevant temporal scale. We present the methodology behind and an initial implementation of a novel open-source computational framework for construction, simulation, and analysis of models consisting of millions of neurons on high-performance computing systems, based on the NEURON and CoreNEURON simulators (Carnevale and Hines, 2006, Kumbhar et al., 2019). This framework uses the HDF5 data format and software library (HDF Group, 2021) and includes a data format for storing morphological, synaptic, and connectivity information of large neuronal network models, and an accompanying open-source software library that provides efficient, scalable parallel storage and MPI-based data movement capabilities. We outline our approaches for constructing detailed large-scale biophysical models with topographical connectivity and input stimuli, and present simulation results obtained with a full-scale model of the dentate gyrus constructed with our framework. The model generates sparse and spatially selective population activity that fits well with in-vivo experimental data. Moreover, our approach is fully general and can be applied to modeling other regions of the hippocampal formation in order to rapidly evaluate specific hypotheses about large-scale neural architectural features." @default.
• W3208022770 created "2021-11-08" @default.
• W3208022770 creator A5047515706 @default.
• W3208022770 creator A5049385021 @default.
• W3208022770 creator A5052126060 @default.
• W3208022770 creator A5054420671 @default.
• W3208022770 creator A5056093714 @default.
• W3208022770 creator A5072019560 @default.
• W3208022770 creator A5076636028 @default.
• W3208022770 creator A5079470342 @default.
• W3208022770 date "2021-11-04" @default.
• W3208022770 modified "2023-09-23" @default.
• W3208022770 title "Towards a general framework for modeling large-scale biophysical neuronal networks: a full-scale computational model of the rat dentate gyrus" @default.
• W3208022770 cites W1506123947 @default.
• W3208022770 cites W1515390428 @default.
• W3208022770 cites W1572294349 @default.
• W3208022770 cites W1861463350 @default.
• W3208022770 cites W1868445472 @default.
• W3208022770 cites W1921182138 @default.
• W3208022770 cites W1965210407 @default.
• W3208022770 cites W1968743318 @default.
• W3208022770 cites W1969677319 @default.
• W3208022770 cites W1970792572 @default.
• W3208022770 cites W1971452080 @default.
• W3208022770 cites W1972144214 @default.
• W3208022770 cites W1975334015 @default.
• W3208022770 cites W1977662196 @default.
• W3208022770 cites W1983886273 @default.
• W3208022770 cites W1987775243 @default.
• W3208022770 cites W1997355517 @default.
• W3208022770 cites W1997692559 @default.
• W3208022770 cites W2012132665 @default.
• W3208022770 cites W2012898751 @default.
• W3208022770 cites W2013427111 @default.
• W3208022770 cites W2019633617 @default.
• W3208022770 cites W2025457757 @default.
• W3208022770 cites W2027205525 @default.
• W3208022770 cites W2029267947 @default.
• W3208022770 cites W2034664267 @default.
• W3208022770 cites W2051434435 @default.
• W3208022770 cites W2052473688 @default.
• W3208022770 cites W2058022492 @default.
• W3208022770 cites W2065227339 @default.
• W3208022770 cites W2069485678 @default.
• W3208022770 cites W2072843066 @default.
• W3208022770 cites W2074376560 @default.
• W3208022770 cites W2083200599 @default.
• W3208022770 cites W2086091159 @default.
• W3208022770 cites W2088042096 @default.
• W3208022770 cites W2088326170 @default.
• W3208022770 cites W2092580449 @default.
• W3208022770 cites W2107566823 @default.
• W3208022770 cites W2114000527 @default.
• W3208022770 cites W2118516890 @default.
• W3208022770 cites W2120867803 @default.
• W3208022770 cites W2126105956 @default.
• W3208022770 cites W2126587466 @default.
• W3208022770 cites W2130836080 @default.
• W3208022770 cites W2131705496 @default.
• W3208022770 cites W2135650087 @default.
• W3208022770 cites W2145187278 @default.
• W3208022770 cites W2148320506 @default.
• W3208022770 cites W2154174049 @default.
• W3208022770 cites W2154731415 @default.
• W3208022770 cites W2162763711 @default.
• W3208022770 cites W2337193669 @default.
• W3208022770 cites W2408984978 @default.
• W3208022770 cites W2532249807 @default.
• W3208022770 cites W2561068888 @default.
• W3208022770 cites W2728927411 @default.
• W3208022770 cites W2747342617 @default.
• W3208022770 cites W2749595928 @default.
• W3208022770 cites W2773293192 @default.
• W3208022770 cites W2787829706 @default.
• W3208022770 cites W2790696945 @default.
• W3208022770 cites W2941307081 @default.
• W3208022770 cites W2971430069 @default.
• W3208022770 cites W3009954736 @default.
• W3208022770 cites W3099878876 @default.
• W3208022770 cites W3158538702 @default.
• W3208022770 cites W4206810002 @default.
• W3208022770 cites W4214775604 @default.
• W3208022770 cites W4234546939 @default.
• W3208022770 cites W644076287 @default.
• W3208022770 cites W82867098 @default.
• W3208022770 doi "https://doi.org/10.1101/2021.11.02.466940" @default.
• W3208022770 hasPublicationYear "2021" @default.
• W3208022770 type Work @default.
• W3208022770 sameAs 3208022770 @default.
• W3208022770 citedByCount "1" @default.
• W3208022770 countsByYear W32080227702022 @default.
• W3208022770 crossrefType "posted-content" @default.
• W3208022770 hasAuthorship W3208022770A5047515706 @default.
• W3208022770 hasAuthorship W3208022770A5049385021 @default.
• W3208022770 hasAuthorship W3208022770A5052126060 @default.
• W3208022770 hasAuthorship W3208022770A5054420671 @default.
• W3208022770 hasAuthorship W3208022770A5056093714 @default.
• W3208022770 hasAuthorship W3208022770A5072019560 @default.
• W3208022770 hasAuthorship W3208022770A5076636028 @default.
• W3208022770 hasAuthorship W3208022770A5079470342 @default.

• next