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• W3208039712 endingPage "151168" @default.
• W3208039712 startingPage "151168" @default.
• W3208039712 abstract "Drinking water and farm-to-fork pathways have been identified as the predominant environmental pathways associated with human exposure (HE) to Pb. This study integrates a GIS-based survey of metal concentrations in soil and a probabilistic quantitative risk assessment of Pb through the food chain. The case study area was selected in the east of Ireland. A step-wise exposure assessment collated the data for Pb concentration in soil and water media, bioaccumulation of Pb in unprocessed food products, such as potatoes, carrots, green vegetables, and salad vegetables. The daily mean HE to Pb through selected food products was found to be 0.073 mg day-1, where a mean weekly exposure was estimated as 0.0065 mg kg body weight-1 week-1. Multiple risk estimates were used. Hazard Quotient (HQ), Daily Dietary Index (DDI), Daily Intake of Metal (DIM), Health Risk Index (HRI), Target Hazard Quotient (THQ) and Cancer Risk (CR) were found as 0.234 to 0.669, 0.002, 0.0002, 0.020 to 0.057, 0.234 to 0.669, and 0.00001, respectively which signify a low to moderate risk. A sensitivity analysis revealed that intake of potato is the most sensitive parameter of the model, which is positively correlated (coeff. + 0.66) followed by concentration of Pb in the arable soil (+0.49), bioaccumulation in tubers (+0.37), consumption of salad vegetables (+0.20), and consumption of green vegetables (+0.13) (top 5). A back-calculated limit of Pb in the soil (51 mg kg-1) justifies the lower threshold limit of Pb (50-300 mg kg-1) in agricultural soil set by the European Union to mitigate potential bio-transfer into food products. The study concludes there is a low to moderate risk posed by Pb, within the system boundary of the probabilistic model, and highlights the significance of limiting Pb concentrations in the vegetable producing agricultural soil." @default.
• W3208039712 created "2021-11-08" @default.
• W3208039712 creator A5031089093 @default.
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• W3208039712 date "2022-03-01" @default.
• W3208039712 modified "2023-10-01" @default.
• W3208039712 title "Human health risk assessment of lead (Pb) through the environmental-food pathway" @default.
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• W3208039712 doi "https://doi.org/10.1016/j.scitotenv.2021.151168" @default.
• W3208039712 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/34710405" @default.
• W3208039712 hasPublicationYear "2022" @default.
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