Matches in SemOpenAlex for { <https://semopenalex.org/work/W3208096247> ?p ?o ?g. }
Showing items 1 to 80 of
80
with 100 items per page.
- W3208096247 abstract "Abstract Two binuclear selenium adducts ( 5 and 6 ) were designed using molecular docking approach while finding their promising interaction to four angiogenic factor-proteins including COX-1 (Cyclooxygenase-1), VEGF-A (vascular endothelial growth factor A), HIF (Hypoxia-inducible factor) and EGF (human epidermal growth factor). They were consequently synthesized using In-situ coordination approach. The green synthetic approach was employed for coordination as it was carried out in water instead of organic solvents. The synthesized adducts as well as their respective bis-benzimidazolium salts ( 2 and 4 ) were confirmed by 1 H and 13 C-NMR along with FT-IR spectroscopy. The both were, then, subjected to In-vitro anticancer activities against breast adenocarcinoma cell line (MCF-7), cervical cancer cell line (Hela), mouse melanoma cell line (B16F10) and retinal ganglion cell line (RGC-5) using MTT assay while comparing their activities with a commercially established standard-drug 5-Fluorouracil. However, the exceptional activities of both adducts and bis-benzimidazolium salts were explored." @default.
- W3208096247 created "2021-11-08" @default.
- W3208096247 creator A5025314978 @default.
- W3208096247 creator A5044325531 @default.
- W3208096247 creator A5052061079 @default.
- W3208096247 creator A5070722495 @default.
- W3208096247 creator A5071948044 @default.
- W3208096247 creator A5090948982 @default.
- W3208096247 date "2021-07-08" @default.
- W3208096247 modified "2023-10-11" @default.
- W3208096247 title "Docking-designed Green Synthesis and In-Vitro Anticancer Studies of New Binuclear Se-N-Heterocyclic Carbene Adducts and their Azolium Salts" @default.
- W3208096247 doi "https://doi.org/10.21203/rs.3.rs-678554/v1" @default.
- W3208096247 hasPublicationYear "2021" @default.
- W3208096247 type Work @default.
- W3208096247 sameAs 3208096247 @default.
- W3208096247 citedByCount "1" @default.
- W3208096247 countsByYear W32080962472022 @default.
- W3208096247 crossrefType "posted-content" @default.
- W3208096247 hasAuthorship W3208096247A5025314978 @default.
- W3208096247 hasAuthorship W3208096247A5044325531 @default.
- W3208096247 hasAuthorship W3208096247A5052061079 @default.
- W3208096247 hasAuthorship W3208096247A5070722495 @default.
- W3208096247 hasAuthorship W3208096247A5071948044 @default.
- W3208096247 hasAuthorship W3208096247A5090948982 @default.
- W3208096247 hasBestOaLocation W32080962471 @default.
- W3208096247 hasConcept C108204754 @default.
- W3208096247 hasConcept C159110408 @default.
- W3208096247 hasConcept C161790260 @default.
- W3208096247 hasConcept C167734588 @default.
- W3208096247 hasConcept C178790620 @default.
- W3208096247 hasConcept C185592680 @default.
- W3208096247 hasConcept C202751555 @default.
- W3208096247 hasConcept C2777025900 @default.
- W3208096247 hasConcept C2777164566 @default.
- W3208096247 hasConcept C2777366897 @default.
- W3208096247 hasConcept C2780783641 @default.
- W3208096247 hasConcept C41685203 @default.
- W3208096247 hasConcept C502942594 @default.
- W3208096247 hasConcept C54355233 @default.
- W3208096247 hasConcept C55493867 @default.
- W3208096247 hasConcept C71240020 @default.
- W3208096247 hasConcept C71924100 @default.
- W3208096247 hasConcept C81885089 @default.
- W3208096247 hasConcept C86803240 @default.
- W3208096247 hasConceptScore W3208096247C108204754 @default.
- W3208096247 hasConceptScore W3208096247C159110408 @default.
- W3208096247 hasConceptScore W3208096247C161790260 @default.
- W3208096247 hasConceptScore W3208096247C167734588 @default.
- W3208096247 hasConceptScore W3208096247C178790620 @default.
- W3208096247 hasConceptScore W3208096247C185592680 @default.
- W3208096247 hasConceptScore W3208096247C202751555 @default.
- W3208096247 hasConceptScore W3208096247C2777025900 @default.
- W3208096247 hasConceptScore W3208096247C2777164566 @default.
- W3208096247 hasConceptScore W3208096247C2777366897 @default.
- W3208096247 hasConceptScore W3208096247C2780783641 @default.
- W3208096247 hasConceptScore W3208096247C41685203 @default.
- W3208096247 hasConceptScore W3208096247C502942594 @default.
- W3208096247 hasConceptScore W3208096247C54355233 @default.
- W3208096247 hasConceptScore W3208096247C55493867 @default.
- W3208096247 hasConceptScore W3208096247C71240020 @default.
- W3208096247 hasConceptScore W3208096247C71924100 @default.
- W3208096247 hasConceptScore W3208096247C81885089 @default.
- W3208096247 hasConceptScore W3208096247C86803240 @default.
- W3208096247 hasLocation W32080962471 @default.
- W3208096247 hasOpenAccess W3208096247 @default.
- W3208096247 hasPrimaryLocation W32080962471 @default.
- W3208096247 hasRelatedWork W1492597319 @default.
- W3208096247 hasRelatedWork W2098842804 @default.
- W3208096247 hasRelatedWork W2362773407 @default.
- W3208096247 hasRelatedWork W2363151046 @default.
- W3208096247 hasRelatedWork W2371230212 @default.
- W3208096247 hasRelatedWork W2427319065 @default.
- W3208096247 hasRelatedWork W2542292710 @default.
- W3208096247 hasRelatedWork W2942894374 @default.
- W3208096247 hasRelatedWork W2950255396 @default.
- W3208096247 hasRelatedWork W3001361328 @default.
- W3208096247 isParatext "false" @default.
- W3208096247 isRetracted "false" @default.
- W3208096247 magId "3208096247" @default.
- W3208096247 workType "article" @default.