Matches in SemOpenAlex for { <https://semopenalex.org/work/W3208106232> ?p ?o ?g. }
- W3208106232 endingPage "1340" @default.
- W3208106232 startingPage "1340" @default.
- W3208106232 abstract "The emergence of carbapenem-resistant Acinetobacter baumannii (CRAB) has now become a global sentinel event. CRAB infections often instigate severe clinical complications and are potentially fatal, especially for debilitated patients. The present study aimed to conduct molecular characterization on CRAB isolated from patients in the intensive care unit from 2015 to 2016 and determine the risk factors associated with patients' mortality. One hundred CRAB isolates were retrospectively selected and included in this study. Antimicrobial susceptibility testing showed that all isolates remained susceptible to colistin, even though 62% of them conferred resistance to all other classes of antibiotics tested. OXA carbapenemase gene was found to be the predominant carbapenemase gene, with 99% of the isolates coharbouring blaOXA-23-like and blaOXA-51-like carbapenemase genes. All isolates were carrying intact CarO genes, with the presence of various degree of nucleotide insertion, deletion and substitution. Overall, PFGE subtyped the isolates into 13 distinct pulsotypes, with the presence of 2 predominant pulsotypes. Univariate analysis implied that age, infection/colonization by CRAB, ethnicity, comorbidity and CRAB specimen source were significantly associated with in-hospital mortality. Multivariate analysis identified a higher risk of mortality for patients who are of Chinese ethnicity with diabetes as an underlying disease. As CRAB infection could lead to high rate of mortality, comprehensive infection control measures are needed to minimize the spread of this pathogen." @default.
- W3208106232 created "2021-11-08" @default.
- W3208106232 creator A5009172674 @default.
- W3208106232 creator A5012312078 @default.
- W3208106232 creator A5013185568 @default.
- W3208106232 creator A5020522975 @default.
- W3208106232 creator A5024004168 @default.
- W3208106232 creator A5077492704 @default.
- W3208106232 date "2021-11-02" @default.
- W3208106232 modified "2023-10-12" @default.
- W3208106232 title "Molecular Characterization of Carbapenem-Resistant Acinetobacter baumannii Isolated from the Intensive Care Unit in a Tertiary Teaching Hospital in Malaysia" @default.
- W3208106232 cites W1966899975 @default.
- W3208106232 cites W1984641925 @default.
- W3208106232 cites W1997495012 @default.
- W3208106232 cites W2024263059 @default.
- W3208106232 cites W2025416505 @default.
- W3208106232 cites W2088690349 @default.
- W3208106232 cites W2095077206 @default.
- W3208106232 cites W2118328361 @default.
- W3208106232 cites W2118756050 @default.
- W3208106232 cites W2121998313 @default.
- W3208106232 cites W2126750975 @default.
- W3208106232 cites W2131367679 @default.
- W3208106232 cites W2136700350 @default.
- W3208106232 cites W2137108244 @default.
- W3208106232 cites W2159435953 @default.
- W3208106232 cites W2206849125 @default.
- W3208106232 cites W2215192004 @default.
- W3208106232 cites W2260530806 @default.
- W3208106232 cites W2262255025 @default.
- W3208106232 cites W2276685641 @default.
- W3208106232 cites W2281387347 @default.
- W3208106232 cites W2533596066 @default.
- W3208106232 cites W2570388282 @default.
- W3208106232 cites W2578361705 @default.
- W3208106232 cites W2620574368 @default.
- W3208106232 cites W2737953146 @default.
- W3208106232 cites W2766228807 @default.
- W3208106232 cites W2775049162 @default.
- W3208106232 cites W2783346327 @default.
- W3208106232 cites W2792776994 @default.
- W3208106232 cites W2901414189 @default.
- W3208106232 cites W2911007809 @default.
- W3208106232 cites W2925136326 @default.
- W3208106232 cites W2926708285 @default.
- W3208106232 cites W2939178605 @default.
- W3208106232 cites W2948049517 @default.
- W3208106232 cites W2952381396 @default.
- W3208106232 cites W2973364180 @default.
- W3208106232 cites W2975239097 @default.
- W3208106232 cites W2982310312 @default.
- W3208106232 cites W2984809510 @default.
- W3208106232 cites W2994575890 @default.
- W3208106232 cites W3020428567 @default.
- W3208106232 cites W3043819792 @default.
- W3208106232 cites W3085917842 @default.
- W3208106232 cites W3112151723 @default.
- W3208106232 cites W3201535262 @default.
- W3208106232 cites W4211219273 @default.
- W3208106232 cites W4300200509 @default.
- W3208106232 doi "https://doi.org/10.3390/antibiotics10111340" @default.
- W3208106232 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/8615160" @default.
- W3208106232 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/34827278" @default.
- W3208106232 hasPublicationYear "2021" @default.
- W3208106232 type Work @default.
- W3208106232 sameAs 3208106232 @default.
- W3208106232 citedByCount "3" @default.
- W3208106232 countsByYear W32081062322022 @default.
- W3208106232 countsByYear W32081062322023 @default.
- W3208106232 crossrefType "journal-article" @default.
- W3208106232 hasAuthorship W3208106232A5009172674 @default.
- W3208106232 hasAuthorship W3208106232A5012312078 @default.
- W3208106232 hasAuthorship W3208106232A5013185568 @default.
- W3208106232 hasAuthorship W3208106232A5020522975 @default.
- W3208106232 hasAuthorship W3208106232A5024004168 @default.
- W3208106232 hasAuthorship W3208106232A5077492704 @default.
- W3208106232 hasBestOaLocation W32081062321 @default.
- W3208106232 hasConcept C126322002 @default.
- W3208106232 hasConcept C2776315533 @default.
- W3208106232 hasConcept C2776376669 @default.
- W3208106232 hasConcept C2776685102 @default.
- W3208106232 hasConcept C2777637488 @default.
- W3208106232 hasConcept C2779259085 @default.
- W3208106232 hasConcept C501593827 @default.
- W3208106232 hasConcept C523546767 @default.
- W3208106232 hasConcept C54355233 @default.
- W3208106232 hasConcept C71924100 @default.
- W3208106232 hasConcept C86803240 @default.
- W3208106232 hasConcept C89423630 @default.
- W3208106232 hasConceptScore W3208106232C126322002 @default.
- W3208106232 hasConceptScore W3208106232C2776315533 @default.
- W3208106232 hasConceptScore W3208106232C2776376669 @default.
- W3208106232 hasConceptScore W3208106232C2776685102 @default.
- W3208106232 hasConceptScore W3208106232C2777637488 @default.
- W3208106232 hasConceptScore W3208106232C2779259085 @default.
- W3208106232 hasConceptScore W3208106232C501593827 @default.
- W3208106232 hasConceptScore W3208106232C523546767 @default.
- W3208106232 hasConceptScore W3208106232C54355233 @default.