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• W3208174832 abstract "Introduction: Many cirrhosis patients undergo colonoscopy as screening colonoscopy is often required before liver transplantation, but cirrhosis causes immune dysfunction and coagulopathy and can be a risk to this population. There is a lack of studies on how the overall outcome of inpatient colonoscopy is affected by cirrhosis. Thus, this study investigates the impact of cirrhosis on the outcomes of colonoscopy at a national level. Methods: Adult patients hospitalized with a procedure diagnosis of colonoscopy from the National Inpatient Sample, Healthcare Cost and Utilization Project, Agency for Healthcare Research and Quality 2014 were selected. Diagnoses were identified by using ICD-9 CM codes. Patient demographics and outcomes of colonoscopy were compared between the groups with and without cirrhosis. In addition, subgroup analysis was performed to evaluate the differences in outcomes between compensated and decompensated cirrhosis. Multivariate logistic regression analysis was performed to determine if cirrhosis is an independent predictor for the outcomes, adjusting for age, sex, race, and the Charlson Comorbidity Index (CCI). Results: Patients with cirrhosis had longer length of stay (7.8 days vs 6.5 days, p < 0.05), had higher total hospital charge ($79,762 vs $59,788, p < 0.05), and had higher inpatient mortality (3.6% vs 1.2%, p < 0.05), all of which were affected solely by decompensated cirrhosis. Compensated cirrhosis was not associated with these outcomes. After adjusting for age, sex, race, and the CCI, cirrhosis was an independent risk factor for hemorrhage (aOR 1.32, 95% CI: 1.18-1.48, p < 0.05) and inpatient mortality (aOR 2.98, 95% CI: 2.28-3.89, p < 0.05). Both compensated and decompensated cirrhosis had a higher risk of hemorrhage. Subgroup analysis showed that decompensated cirrhosis was associated with a higher risk of sepsis, while compensated cirrhosis was associated with a lower risk of sepsis. Conclusion: Cirrhosis was associated with worse outcomes of inpatient colonoscopy overall, although differences in outcomes existed between compensated and decompensated cirrhosis. Thus, understanding the impact of cirrhosis and the differences between compensated and decompensated cirrhosis can be helpful for risk assessment and surveillance in patients undergoing inpatient colonoscopy." @default.
• W3208174832 created "2021-11-08" @default.
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• W3208174832 date "2021-10-01" @default.
• W3208174832 modified "2023-09-27" @default.
• W3208174832 title "S3394 Impact of Cirrhosis on the Outcomes of Patients Undergoing Inpatient Colonoscopy: A Nationwide Analysis" @default.
• W3208174832 doi "https://doi.org/10.14309/01.ajg.0000787108.05263.dc" @default.
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