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- W3208221395 endingPage "1156" @default.
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- W3208221395 abstract "Binge eating involves consuming excessive amounts of food within a discrete period of time and is associated with significant impairments in binge-eating disorder and bulimia nervosa. While research on clinical binge eating has provided valuable aetiological insights, animal models allow for closer examination of environmental, biological, and developmental risk factors. Numerous animal models of binge eating exist and differ widely in operational definitions of bingeing, animal characteristics and methodological parameters. The current review aimed to synthesise the available published evidence on these models. A systematic review of binge definitions in 170 articles found most studies displayed good face validity. Meta-analyses on 150 articles confirmed that the amount of food or drink consumed by animals under binge conditions was larger than that of non-binge conditions across many protocols. The meta-regression revealed species, strain, and sex moderated binge effect size, with the largest effect observed in studies with female animals and mice. Risk of bias assessment identified that improved reporting of allocation, baseline characteristics and outcome assessment is required in future studies." @default.
- W3208221395 created "2021-11-08" @default.
- W3208221395 creator A5012842877 @default.
- W3208221395 creator A5028329389 @default.
- W3208221395 creator A5048299435 @default.
- W3208221395 creator A5062322706 @default.
- W3208221395 date "2022-01-01" @default.
- W3208221395 modified "2023-09-26" @default.
- W3208221395 title "A systematic review and meta-analysis of animal models of binge eating - Part 1: Definitions and food/drink intake outcomes" @default.
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