Matches in SemOpenAlex for { <https://semopenalex.org/work/W3208247915> ?p ?o ?g. }
Showing items 1 to 54 of
54
with 100 items per page.
- W3208247915 abstract "SLE (Systemic Lupus Erythematosus) is one of autoimmune disease in which the immune system attacksits own tissues, causing widespread inflammation and tissue damage in the affected organs. Etiology andpathogenesis are not clearly mention until now by the scientist, but environmental factor is contribute todevelopment of Lupus and Flare disease. The objective of this study to explain the relationship betweenenvironmental factors and pathogenesis development of SLE, and how the Epigallocatechin-3-Gallate(EGCG) can protect or prevent of organs damage and environmental effects.Method: The research design of this study was used literature review. The data sources collected fromElectronic database in Pubmed, Sage, Google Scholar and website of science including reports, journals andmostly published in the last 10 years.Results: The pathomechanism of SLE was influenced by environmental factors and this was caused anincreasing of oxidative stress, chronic inflammation, dysregulation of immune system and decreased theclean of immune complex and apoptosis of cells. The production of autoantibodies and immune complex arerelated with target tissue with is it was caused chronic inflammation and the end it caused irreversible damagein glomerulus of the kidneys, arteries, lungs and other tissues. EGCG plays a protecting role in environmentalfactors as a trigger because it works as an antioxidant, anti-inflammatory and immunomudulator. So EGCGcan as a potential agent to protect SLE.Conclusion: Environmental factors plays an important role as a triger of SLE and flare. Moreover, EGCG asa potential agent to protect the presence of oxidative stress, inflammation and immune dysregulation." @default.
- W3208247915 created "2021-11-08" @default.
- W3208247915 date "2021-04-13" @default.
- W3208247915 modified "2023-09-26" @default.
- W3208247915 title "Environmental Factors and Protective Effects of Epigallocatechin-3-Gallate to Systemic Lupus Eritematosus: A Review Study" @default.
- W3208247915 doi "https://doi.org/10.37506/ijfmt.v15i2.14750" @default.
- W3208247915 hasPublicationYear "2021" @default.
- W3208247915 type Work @default.
- W3208247915 sameAs 3208247915 @default.
- W3208247915 citedByCount "0" @default.
- W3208247915 crossrefType "journal-article" @default.
- W3208247915 hasConcept C126322002 @default.
- W3208247915 hasConcept C142724271 @default.
- W3208247915 hasConcept C159654299 @default.
- W3208247915 hasConcept C163764329 @default.
- W3208247915 hasConcept C203014093 @default.
- W3208247915 hasConcept C2776151105 @default.
- W3208247915 hasConcept C2776252253 @default.
- W3208247915 hasConcept C2776912625 @default.
- W3208247915 hasConcept C2776914184 @default.
- W3208247915 hasConcept C2779134260 @default.
- W3208247915 hasConcept C2780194698 @default.
- W3208247915 hasConcept C71924100 @default.
- W3208247915 hasConcept C8891405 @default.
- W3208247915 hasConceptScore W3208247915C126322002 @default.
- W3208247915 hasConceptScore W3208247915C142724271 @default.
- W3208247915 hasConceptScore W3208247915C159654299 @default.
- W3208247915 hasConceptScore W3208247915C163764329 @default.
- W3208247915 hasConceptScore W3208247915C203014093 @default.
- W3208247915 hasConceptScore W3208247915C2776151105 @default.
- W3208247915 hasConceptScore W3208247915C2776252253 @default.
- W3208247915 hasConceptScore W3208247915C2776912625 @default.
- W3208247915 hasConceptScore W3208247915C2776914184 @default.
- W3208247915 hasConceptScore W3208247915C2779134260 @default.
- W3208247915 hasConceptScore W3208247915C2780194698 @default.
- W3208247915 hasConceptScore W3208247915C71924100 @default.
- W3208247915 hasConceptScore W3208247915C8891405 @default.
- W3208247915 hasLocation W32082479151 @default.
- W3208247915 hasOpenAccess W3208247915 @default.
- W3208247915 hasPrimaryLocation W32082479151 @default.
- W3208247915 hasRelatedWork W13490693 @default.
- W3208247915 hasRelatedWork W14584756 @default.
- W3208247915 hasRelatedWork W15087749 @default.
- W3208247915 hasRelatedWork W16026736 @default.
- W3208247915 hasRelatedWork W16227375 @default.
- W3208247915 hasRelatedWork W1938957 @default.
- W3208247915 hasRelatedWork W20486147 @default.
- W3208247915 hasRelatedWork W2748689 @default.
- W3208247915 hasRelatedWork W3430926 @default.
- W3208247915 hasRelatedWork W6548557 @default.
- W3208247915 isParatext "false" @default.
- W3208247915 isRetracted "false" @default.
- W3208247915 magId "3208247915" @default.
- W3208247915 workType "article" @default.