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- W3208278675 abstract "Designing efficacious formulations for oral route of drug delivery has been challenging but still warranted because of its high patient compliance. However, drugs in pipeline or any new chemical entities being discovered have always faced key challenges of optimum solubility and permeability without which a product cannot show the claimed activity or even enter the trials. Though there are several intriguing choices of drug development available, lipid-based formulations are gaining popularity owing to their ease of manufacturing and efficacious results. Further, narrowing the base of lipid-formulations which have gained acceptance are micro- and nanoemulsions, whose bars have been raised higher with the introduction of “self-emulsifying drug delivery system” (SEDDS), which has swept off the bits-and-flaws of conventional emulsion. Therefore, this chapter is an attempt to cover all the aspects of SEDDS formulation including “self-micro-emulsifying drug delivery system (SMEDDS)” and “self-nano-emulsifying drug delivery system (SNEDDS)”; a deep dive in its formulation criteria, selection of suitable candidate and components, self-emulsification process, probable fate of the formulation in vivo, transformation techniques, evaluation parameters, 130new approaches in pipeline, dosage forms that can be prepared, challenging aspects lingering around, extensive researches done since last decade to present and patents being granted so far." @default.
- W3208278675 created "2021-11-08" @default.
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- W3208278675 date "2021-10-29" @default.
- W3208278675 modified "2023-09-24" @default.
- W3208278675 title "Self-Emulsifying Drug Delivery Systems: A Strategy to Improve the Bioavailability of Hydrophobic Drugs" @default.
- W3208278675 doi "https://doi.org/10.1201/9781003160588-6" @default.
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