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- W3208300584 abstract "Genetic variants in apolipoprotein L1 (APOL1) — present only in individuals of African ancestry — contribute to increased susceptibility to sepsis and COVID-19. APOL1 variants impair mitophagy in endothelial cells, allowing the release of mitochondrial DNA that activates inflammasome and nucleotide sensing pathways." @default.
- W3208300584 created "2021-11-08" @default.
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- W3208300584 date "2021-10-27" @default.
- W3208300584 modified "2023-09-25" @default.
- W3208300584 title "APOL1 variants contribute to racial disparity in sepsis" @default.
- W3208300584 cites W3207642580 @default.
- W3208300584 doi "https://doi.org/10.1038/s41577-021-00647-3" @default.
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