FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W3208306650> ?p ?o ?g. }

• W3208306650 endingPage "243" @default.
• W3208306650 startingPage "235" @default.
• W3208306650 abstract "Plasma neutrophil gelatinase-associated lipocalin (pNGAL) has been investigated extensively in acute kidney injury. This study investigated its pathophysiological significance and utility as marker for graft failure and mortality in stable kidney transplant recipients (KTR).Baseline pNGAL was measured in 698 KTR (58% male, age 53 ± 13 years, estimated glomerular filtration rate 52.4 ± 20.4 mL/min/1.73 m2) at median 5.4 (interquartile range 1.8-12.0) years after transplantation, enrolled in the prospective TransplantLines Food and Nutrition Biobank and Cohort Study.pNGAL concentrations were higher in males, younger patients, patients with a deceased-donor kidney and higher serum creatinine. Independent of these, pNGAL was positively associated with urinary protein excretion, systemic inflammation parameters and calcineurin inhibitor use. During median follow-up of 5.3 (4.5-6.0) years, death-censored graft failure rates were 3.9%, 7.3% and 25.0% across increasing tertiles of pNGAL (Plog-rank < 0.001). Cox-regression analyses showed no independent associations of pNGAL with mortality, but strong associations with graft failure (hazard ratio, per doubling 4.16; 95% confidence interval 3.03-5.71; P < 0.001), which remained independent of adjustment for confounders. These associations were present only in patients with pre-existent proteinuria and poor kidney function.pNGAL is associated with parameters of kidney graft damage and with graft failure. The latter association is particularly present in KTR with pre-existent poor kidney function and proteinuria. Trial Registration: ClinicalTrials.gov NCT02811835." @default.
• W3208306650 created "2021-11-08" @default.
• W3208306650 creator A5001204318 @default.
• W3208306650 creator A5010367070 @default.
• W3208306650 creator A5012516011 @default.
• W3208306650 creator A5016779156 @default.
• W3208306650 creator A5038949732 @default.
• W3208306650 creator A5045287290 @default.
• W3208306650 creator A5050035372 @default.
• W3208306650 creator A5053126771 @default.
• W3208306650 creator A5055740789 @default.
• W3208306650 creator A5070151669 @default.
• W3208306650 creator A5072822314 @default.
• W3208306650 creator A5088158212 @default.
• W3208306650 date "2021-11-08" @default.
• W3208306650 modified "2023-09-24" @default.
• W3208306650 title "Plasma neutrophil gelatinase-associated lipocalin and kidney graft outcome" @default.
• W3208306650 cites W1894980006 @default.
• W3208306650 cites W1979646197 @default.
• W3208306650 cites W1995591432 @default.
• W3208306650 cites W2003018642 @default.
• W3208306650 cites W2011726320 @default.
• W3208306650 cites W2017948978 @default.
• W3208306650 cites W2043449104 @default.
• W3208306650 cites W2044678071 @default.
• W3208306650 cites W2056252610 @default.
• W3208306650 cites W2061786959 @default.
• W3208306650 cites W2103314755 @default.
• W3208306650 cites W2118986705 @default.
• W3208306650 cites W2119129699 @default.
• W3208306650 cites W2140374361 @default.
• W3208306650 cites W2141341148 @default.
• W3208306650 cites W2143262001 @default.
• W3208306650 cites W2155965977 @default.
• W3208306650 cites W2161922215 @default.
• W3208306650 cites W2170433159 @default.
• W3208306650 cites W2275187515 @default.
• W3208306650 cites W2521162194 @default.
• W3208306650 cites W2607031541 @default.
• W3208306650 cites W2607793891 @default.
• W3208306650 cites W2616339965 @default.
• W3208306650 cites W2781855627 @default.
• W3208306650 cites W2802965191 @default.
• W3208306650 cites W2920667541 @default.
• W3208306650 cites W2974347135 @default.
• W3208306650 cites W2980320585 @default.
• W3208306650 cites W4212929213 @default.
• W3208306650 cites W65803437 @default.
• W3208306650 doi "https://doi.org/10.1093/ckj/sfab219" @default.
• W3208306650 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/35145638" @default.
• W3208306650 hasPublicationYear "2021" @default.
• W3208306650 type Work @default.
• W3208306650 sameAs 3208306650 @default.
• W3208306650 citedByCount "3" @default.
• W3208306650 countsByYear W32083066502022 @default.
• W3208306650 countsByYear W32083066502023 @default.
• W3208306650 crossrefType "journal-article" @default.
• W3208306650 hasAuthorship W3208306650A5001204318 @default.
• W3208306650 hasAuthorship W3208306650A5010367070 @default.
• W3208306650 hasAuthorship W3208306650A5012516011 @default.
• W3208306650 hasAuthorship W3208306650A5016779156 @default.
• W3208306650 hasAuthorship W3208306650A5038949732 @default.
• W3208306650 hasAuthorship W3208306650A5045287290 @default.
• W3208306650 hasAuthorship W3208306650A5050035372 @default.
• W3208306650 hasAuthorship W3208306650A5053126771 @default.
• W3208306650 hasAuthorship W3208306650A5055740789 @default.
• W3208306650 hasAuthorship W3208306650A5070151669 @default.
• W3208306650 hasAuthorship W3208306650A5072822314 @default.
• W3208306650 hasAuthorship W3208306650A5088158212 @default.
• W3208306650 hasBestOaLocation W32083066501 @default.
• W3208306650 hasConcept C119060515 @default.
• W3208306650 hasConcept C126322002 @default.
• W3208306650 hasConcept C126894567 @default.
• W3208306650 hasConcept C159641895 @default.
• W3208306650 hasConcept C188816634 @default.
• W3208306650 hasConcept C207103383 @default.
• W3208306650 hasConcept C2779561371 @default.
• W3208306650 hasConcept C2780091579 @default.
• W3208306650 hasConcept C2780303639 @default.
• W3208306650 hasConcept C2780306776 @default.
• W3208306650 hasConcept C2780472472 @default.
• W3208306650 hasConcept C2911091166 @default.
• W3208306650 hasConcept C44249647 @default.
• W3208306650 hasConcept C50382708 @default.
• W3208306650 hasConcept C71924100 @default.
• W3208306650 hasConcept C90924648 @default.
• W3208306650 hasConceptScore W3208306650C119060515 @default.
• W3208306650 hasConceptScore W3208306650C126322002 @default.
• W3208306650 hasConceptScore W3208306650C126894567 @default.
• W3208306650 hasConceptScore W3208306650C159641895 @default.
• W3208306650 hasConceptScore W3208306650C188816634 @default.
• W3208306650 hasConceptScore W3208306650C207103383 @default.
• W3208306650 hasConceptScore W3208306650C2779561371 @default.
• W3208306650 hasConceptScore W3208306650C2780091579 @default.
• W3208306650 hasConceptScore W3208306650C2780303639 @default.
• W3208306650 hasConceptScore W3208306650C2780306776 @default.
• W3208306650 hasConceptScore W3208306650C2780472472 @default.
• W3208306650 hasConceptScore W3208306650C2911091166 @default.

• next