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- W3208308951 abstract "Introduction: Gastrointestinal lymphomas originate in the gastrointestinal tract. These can be primary or as a part of other causes of lymphomas. The incidence of lymphomas has increased steadily in the last few years. The stomach is most commonly involved. This is followed by small intestine and ileocecal region. Gastrointestinal (GI) hemorrhage as a direct cause of lymphoma is rare. However, bleeding is generally associated with adverse outcomes. Here we examine data obtained from the National Inpatient Sample (NIS) to understand outcomes of GI bleeding in patients with GI lymphomas. Methods: NIS surveys 20% of all hospitalizations for a particular year. We identified ICD-10 codes for patients with any history of GI lymphomas and history of any cause of GI hemorrhage. Possible contributing factors were added to limit confounders in the analysis. The primary outcome was defined as inpatient mortality. Secondary outcomes were hospital length of stay and total charge. We performed a multivariable analysis using STATA MP 16.1. The results are reported below. Results: The study included 1172 patients who were adults ( >18) with any diagnosis of gastrointestinal lymphoma. After weighing the total population is 5860 patients. Among these patients, [525(9%)] had presented with gastrointestinal hemorrhage. Of the patients with GI Bleed, 5% patients died. The mean age of the population was 66 years. 41% of this population was female. Multivariable analysis on mortality shows that GI lymphoma patients with a history of gastrointestinal hemorrhage had higher odds of inpatient mortality independent of other variables in the analysis (Odds Ratio (OR) 2.57, 95% Confidence Intervals (CI) 1.22 – 5.40), P = 0.013). Prior history of chemotherapy was associated with higher odds of mortality but this result did not reach statistical significance. Increasing age is associated with higher odds of mortality (OR 1.04, 95% CI 1.02 – 1.07). Hospital length of stay was higher in our cohort by ∼ 5 days (Coeff. 4.86, 95% CI 2.25 – 7.47). Similarly, the total charge was higher (72298.57, 95% CI 22456.61 – 122140.5). Other covariables in the analysis did not contribute to a statistically significant outcome. Conclusion: Patients admitted with any diagnosis of gastrointestinal lymphoma have higher odds of mortality, higher length of stay, and hospital charge if they have a concomitant diagnosis of any gastrointestinal hemorrhage." @default.
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- W3208308951 date "2021-10-01" @default.
- W3208308951 modified "2023-10-16" @default.
- W3208308951 title "S3297 Effect of Gastrointestinal Hemorrhage in Patients Admitted With Gastrointestinal Lymphomas" @default.
- W3208308951 doi "https://doi.org/10.14309/01.ajg.0000786720.83205.6b" @default.
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