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• W3208328863 abstract "Multiple previous analyses have exposed the underrepresentation of minority patients in clinical trials across all medical disciplines, including oncology. An examination of all completed cancer trials reported on ClinicalTrials.gov from 2003 to 2016 showed that African-American (AA) and Hispanic patients were less likely to be enrolled than non-Hispanic White patients, with an even greater difference compared with trials reported from 1996 to 2002. 1 Duma N Vera Aguilera J Paludo J et al. Representation of minorities and women in oncology clinical trials: Review of the past 14 years. J Oncol Pract. 2018; 14: e1-e10 Crossref PubMed Scopus (133) Google Scholar A study of all trials supporting Food and Drug Administration-approved oncology drugs from 2008 to 2018 showed that Black and Hispanic patients were underrepresented compared with their proportions of US cancer incidence versus White and Asian patients (22%, 44%, 98%, and 438% of expected, respectively). 2 Loree JM Anand S Dasari A et al. Disparity of race reporting and representation in clinical trials leading to cancer drug approvals from 2008 to 2018. JAMA Oncol. 2019; 5e191870 Crossref PubMed Scopus (177) Google Scholar Given that trial results drive future therapeutic decision making, these discrepancies are particularly devastating given the increasing diversity of the US population." @default.
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• W3208328863 date "2021-11-01" @default.
• W3208328863 modified "2023-10-15" @default.
• W3208328863 title "A Call to Action: Radiation Oncology Trials and Minority Enrollment" @default.
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• W3208328863 doi "https://doi.org/10.1016/j.prro.2021.06.015" @default.
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