Matches in SemOpenAlex for { <https://semopenalex.org/work/W3208348706> ?p ?o ?g. }
- W3208348706 endingPage "163" @default.
- W3208348706 startingPage "144" @default.
- W3208348706 abstract "SUMMARY Radish, Raphanus sativus L., is an important root crop that is cultivated worldwide. Owing to its evolutionary proximity to Arabidopsis thaliana , radish can be used as a model root crop in research on the molecular basis of agronomic traits. Pithiness is a significant defect that reduces the production of radish with commercial value; however, traditional breeding to eliminate this trait has thus far been unsuccessful. Here, we performed transcriptomics and genotype‐by‐sequencing (GBS)‐based quantitative trait locus (QTL) analyses of radish inbred lines to understand the molecular basis of pithiness in radish roots. The transcriptome data indicated that pithiness likely stems from the response to oxidative stress, leading to cell death of the xylem parenchyma during the root‐thickening process. Subsequently, we narrowed down a list of candidates responsible for pithiness near a major QTL and found polymorphisms in a radish homologue of Arabidopsis ANAC013 (RsNAC013), an endoplasmic reticulum bound NAC transcription factor that is targeted to the nucleus to mediate the mitochondrial retrograde signal. We analysed the effects of polymorphisms in RsNAC013 using Arabidopsis transgenic lines overexpressing RsNAC013 alleles as well as in radish inbred lines bearing these alleles. This analysis indicated that non‐synonymous variations within the coding sequence result in different levels of RsNAC013 activities, thereby providing a genetic condition for root pithiness. The elevated oxidative stress or hypoxia that activates RsNAC013 for mitochondrial signalling enhances this process. Collectively, this study serves as an exemplary case of translational research taking advantage of the extensive information available from a model organism." @default.
- W3208348706 created "2021-11-08" @default.
- W3208348706 creator A5001412882 @default.
- W3208348706 creator A5029734534 @default.
- W3208348706 creator A5039769521 @default.
- W3208348706 creator A5043428880 @default.
- W3208348706 creator A5046327468 @default.
- W3208348706 creator A5058382490 @default.
- W3208348706 creator A5078391644 @default.
- W3208348706 creator A5080891156 @default.
- W3208348706 date "2021-11-16" @default.
- W3208348706 modified "2023-10-17" @default.
- W3208348706 title "Oxidative stress response and programmed cell death guided by NAC013 modulate pithiness in radish taproots" @default.
- W3208348706 cites W1734845526 @default.
- W3208348706 cites W1968294943 @default.
- W3208348706 cites W1970341288 @default.
- W3208348706 cites W1980665099 @default.
- W3208348706 cites W1986113589 @default.
- W3208348706 cites W1999574084 @default.
- W3208348706 cites W2000765714 @default.
- W3208348706 cites W2016487224 @default.
- W3208348706 cites W2027847170 @default.
- W3208348706 cites W2032019813 @default.
- W3208348706 cites W2033856432 @default.
- W3208348706 cites W2037119873 @default.
- W3208348706 cites W2054262102 @default.
- W3208348706 cites W2088364401 @default.
- W3208348706 cites W2096315332 @default.
- W3208348706 cites W2103441770 @default.
- W3208348706 cites W2108234281 @default.
- W3208348706 cites W2108647060 @default.
- W3208348706 cites W2110035718 @default.
- W3208348706 cites W2112320895 @default.
- W3208348706 cites W2113127368 @default.
- W3208348706 cites W2116053845 @default.
- W3208348706 cites W2116290354 @default.
- W3208348706 cites W2119180969 @default.
- W3208348706 cites W2120490508 @default.
- W3208348706 cites W2126034679 @default.
- W3208348706 cites W2131112579 @default.
- W3208348706 cites W2131271579 @default.
- W3208348706 cites W2136974069 @default.
- W3208348706 cites W2143397954 @default.
- W3208348706 cites W2147544895 @default.
- W3208348706 cites W2162072263 @default.
- W3208348706 cites W2170551349 @default.
- W3208348706 cites W2171030481 @default.
- W3208348706 cites W2179438025 @default.
- W3208348706 cites W2182445630 @default.
- W3208348706 cites W2191777053 @default.
- W3208348706 cites W2296992674 @default.
- W3208348706 cites W2299682220 @default.
- W3208348706 cites W2314861289 @default.
- W3208348706 cites W2472226136 @default.
- W3208348706 cites W2597874027 @default.
- W3208348706 cites W2762119308 @default.
- W3208348706 cites W2779640265 @default.
- W3208348706 cites W2784020576 @default.
- W3208348706 cites W2885795579 @default.
- W3208348706 cites W2886464241 @default.
- W3208348706 cites W2889943274 @default.
- W3208348706 cites W2900480349 @default.
- W3208348706 cites W2914362360 @default.
- W3208348706 cites W2922477425 @default.
- W3208348706 cites W2949787845 @default.
- W3208348706 cites W3006710174 @default.
- W3208348706 cites W3023329121 @default.
- W3208348706 cites W3035565400 @default.
- W3208348706 cites W3048864428 @default.
- W3208348706 cites W4246566470 @default.
- W3208348706 cites W45534775 @default.
- W3208348706 doi "https://doi.org/10.1111/tpj.15561" @default.
- W3208348706 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/34724278" @default.
- W3208348706 hasPublicationYear "2021" @default.
- W3208348706 type Work @default.
- W3208348706 sameAs 3208348706 @default.
- W3208348706 citedByCount "2" @default.
- W3208348706 countsByYear W32083487062022 @default.
- W3208348706 crossrefType "journal-article" @default.
- W3208348706 hasAuthorship W3208348706A5001412882 @default.
- W3208348706 hasAuthorship W3208348706A5029734534 @default.
- W3208348706 hasAuthorship W3208348706A5039769521 @default.
- W3208348706 hasAuthorship W3208348706A5043428880 @default.
- W3208348706 hasAuthorship W3208348706A5046327468 @default.
- W3208348706 hasAuthorship W3208348706A5058382490 @default.
- W3208348706 hasAuthorship W3208348706A5078391644 @default.
- W3208348706 hasAuthorship W3208348706A5080891156 @default.
- W3208348706 hasBestOaLocation W32083487062 @default.
- W3208348706 hasConcept C104317684 @default.
- W3208348706 hasConcept C143065580 @default.
- W3208348706 hasConcept C150194340 @default.
- W3208348706 hasConcept C162317418 @default.
- W3208348706 hasConcept C2775988993 @default.
- W3208348706 hasConcept C2779491563 @default.
- W3208348706 hasConcept C2780400012 @default.
- W3208348706 hasConcept C2780416096 @default.
- W3208348706 hasConcept C54355233 @default.
- W3208348706 hasConcept C59822182 @default.