FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W3208361377> ?p ?o ?g. }

• W3208361377 endingPage "737614" @default.
• W3208361377 startingPage "737614" @default.
• W3208361377 abstract "Cynoglossus semilaevis Günther is an important marine aquaculture fish in coastal areas of Northern China, produced by high-density, intensive factory aquaculture. However, large-scale deaths of fish have been associated with clinical signs, including an enlarged abdomen, body surface ulceration, and greyish-white nodules in the spleen and kidney. Strain BS123 was isolated from diseased C. semilaevis , and shown in infection experiments to be associated with 93.3% cumulative mortality, including clinical signs similar to those in naturally diseased fish. The identification, whole-genome sequencing, and comparative genome analysis were carried out in this study. Strain BS123 was identified as Mycobacterium ulcerans ecovar Liflandii based on physiological and biochemical characteristics and genome evolution analysis. It had a full-length genome of 6,228,372 bp and carried a plasmid of 105,858 bp. The genome contained 5934 coding genes, three CRISPR sequences, 28 pathogenic gene islands, and 228 copies of insertion sequence IS 2404 gene. Multi-locus sequence typing (MLST) and ribosomal (r)MLST analysis suggested that the types of strain BS123 were ST123 and rMLST 31,973, respectively. Collinearity analysis showed a good collinear relationship between strain BS123 and M. ulcerans ecovar Liflandii strain 128FXT. A phylogenetic tree showed that the BS123 was closely related to M. ulcerans ecovar Liflandii 128FXT and belonged to the same evolutionary branch as M. ulcerans . Compared with M. marinum (E11), M. ulcerans ecovar Liflandii (128FXT), and M. ulcerans (Agy99) strains, the strain BS123 had 33 unique gene clusters. In summary, M. ulcerans ecovar Liflandii was found to be the cause of disease outbreak in C. semilaevis . This is the first report of an aquaculture marine fish being infected by M. ulcerans ecovar Liflandii. In addition, the genome sequence of this bacterium provides the scientific basis for epidemiological and genetic evolution studies, and for the development of vaccines against M. ulcerans ecovar Liflandii. Thus, this study lays the foundation for the scientific prevention and control of mycobacterial diseases in C. semilaevis . • Mycobacterium ulcerans ecovar Liflandii is the pathogen of the outbreak of farmed Chinese tongue sole. • The whole genome of strain BS123 was sequenced and analyzed. • A large number of CAZy gene families were identified in genome of strain BS123." @default.
• W3208361377 created "2021-11-08" @default.
• W3208361377 creator A5009641074 @default.
• W3208361377 creator A5011756897 @default.
• W3208361377 creator A5016745567 @default.
• W3208361377 creator A5055906780 @default.
• W3208361377 creator A5063106321 @default.
• W3208361377 creator A5088133681 @default.
• W3208361377 creator A5051464962 @default.
• W3208361377 date "2022-02-01" @default.
• W3208361377 modified "2023-09-23" @default.
• W3208361377 title "Identification and genomic analysis of Mycobacterium ulcerans ecovar Liflandii from the farmed Chinese tongue sole, Cynoglossus semilaevis Günther" @default.
• W3208361377 cites W1980411210 @default.
• W3208361377 cites W1980655268 @default.
• W3208361377 cites W1990426706 @default.
• W3208361377 cites W1990484639 @default.
• W3208361377 cites W1991330646 @default.
• W3208361377 cites W2007090411 @default.
• W3208361377 cites W2049621474 @default.
• W3208361377 cites W2069649598 @default.
• W3208361377 cites W2072308015 @default.
• W3208361377 cites W2082476464 @default.
• W3208361377 cites W2103017472 @default.
• W3208361377 cites W2106090237 @default.
• W3208361377 cites W2110788285 @default.
• W3208361377 cites W2117958758 @default.
• W3208361377 cites W2118119639 @default.
• W3208361377 cites W2121621283 @default.
• W3208361377 cites W2125745404 @default.
• W3208361377 cites W2135639274 @default.
• W3208361377 cites W2137721714 @default.
• W3208361377 cites W2138402816 @default.
• W3208361377 cites W2140269967 @default.
• W3208361377 cites W2141818070 @default.
• W3208361377 cites W2148618173 @default.
• W3208361377 cites W2152274483 @default.
• W3208361377 cites W2308145610 @default.
• W3208361377 cites W2343320059 @default.
• W3208361377 cites W2541236043 @default.
• W3208361377 cites W2749742990 @default.
• W3208361377 cites W2787923007 @default.
• W3208361377 cites W2911419689 @default.
• W3208361377 cites W2912223129 @default.
• W3208361377 cites W2951110147 @default.
• W3208361377 cites W3029197725 @default.
• W3208361377 cites W4239954008 @default.
• W3208361377 cites W2790914683 @default.
• W3208361377 doi "https://doi.org/10.1016/j.aquaculture.2021.737614" @default.
• W3208361377 hasPublicationYear "2022" @default.
• W3208361377 type Work @default.
• W3208361377 sameAs 3208361377 @default.
• W3208361377 citedByCount "3" @default.
• W3208361377 countsByYear W32083613772022 @default.
• W3208361377 countsByYear W32083613772023 @default.
• W3208361377 crossrefType "journal-article" @default.
• W3208361377 hasAuthorship W3208361377A5009641074 @default.
• W3208361377 hasAuthorship W3208361377A5011756897 @default.
• W3208361377 hasAuthorship W3208361377A5016745567 @default.
• W3208361377 hasAuthorship W3208361377A5051464962 @default.
• W3208361377 hasAuthorship W3208361377A5055906780 @default.
• W3208361377 hasAuthorship W3208361377A5063106321 @default.
• W3208361377 hasAuthorship W3208361377A5088133681 @default.
• W3208361377 hasConcept C104317684 @default.
• W3208361377 hasConcept C135763542 @default.
• W3208361377 hasConcept C141231307 @default.
• W3208361377 hasConcept C142724271 @default.
• W3208361377 hasConcept C2779134260 @default.
• W3208361377 hasConcept C2780661791 @default.
• W3208361377 hasConcept C54355233 @default.
• W3208361377 hasConcept C71924100 @default.
• W3208361377 hasConcept C77434933 @default.
• W3208361377 hasConcept C86803240 @default.
• W3208361377 hasConceptScore W3208361377C104317684 @default.
• W3208361377 hasConceptScore W3208361377C135763542 @default.
• W3208361377 hasConceptScore W3208361377C141231307 @default.
• W3208361377 hasConceptScore W3208361377C142724271 @default.
• W3208361377 hasConceptScore W3208361377C2779134260 @default.
• W3208361377 hasConceptScore W3208361377C2780661791 @default.
• W3208361377 hasConceptScore W3208361377C54355233 @default.
• W3208361377 hasConceptScore W3208361377C71924100 @default.
• W3208361377 hasConceptScore W3208361377C77434933 @default.
• W3208361377 hasConceptScore W3208361377C86803240 @default.
• W3208361377 hasLocation W32083613771 @default.
• W3208361377 hasOpenAccess W3208361377 @default.
• W3208361377 hasPrimaryLocation W32083613771 @default.
• W3208361377 hasRelatedWork W1442603624 @default.
• W3208361377 hasRelatedWork W1994013149 @default.
• W3208361377 hasRelatedWork W2003922337 @default.
• W3208361377 hasRelatedWork W2069184423 @default.
• W3208361377 hasRelatedWork W2110447214 @default.
• W3208361377 hasRelatedWork W2151912589 @default.
• W3208361377 hasRelatedWork W2975451038 @default.
• W3208361377 hasRelatedWork W4315640719 @default.
• W3208361377 hasRelatedWork W2094069166 @default.
• W3208361377 hasRelatedWork W2187207551 @default.
• W3208361377 hasVolume "548" @default.
• W3208361377 isParatext "false" @default.
• W3208361377 isRetracted "false" @default.

• next