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- W3208379904 abstract "A concise and effective ruthenium-catalyzed asymmetric transfer hydrogenation of β-substituted α-oxobutyrolactones has been developed, delivering a series of cis-β-substituted α-hydroxybutyrolactone derivatives with excellent yields, enantioselectivities, and diastereoselectivities. Two consecutive stereogenic centers were constructed in one step through dynamic kinetic resolution under basic conditions. The reaction could be conducted on a gram scale without loss of activity and enantioselectivity. The reductive products could be easily transformed into useful building blocks." @default.
- W3208379904 created "2021-11-08" @default.
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- W3208379904 date "2021-11-03" @default.
- W3208379904 modified "2023-09-27" @default.
- W3208379904 title "Ruthenium-Catalyzed Asymmetric Transfer Hydrogenation of β-Substituted α-Oxobutyrolactones" @default.
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- W3208379904 doi "https://doi.org/10.1021/acs.joc.1c02156" @default.
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