Matches in SemOpenAlex for { <https://semopenalex.org/work/W3208380091> ?p ?o ?g. }
- W3208380091 abstract "Breast cancer is an aggressive silent disease, representing 11.7% of the diagnosed cancer worldwide, and it is also a leading cause of death in Saudi Arabia. Consequently, microRNAs have emerged recently as potential biomarkers to diagnose and monitor such cases at the molecular level, which tends to be problematic during diagnosis. MicroRNAs are highly conserved non- coding oligonucleotide RNA. Over the last two decades, studies have determined the functional significance of these small RNAs and their impact on cellular development and the interaction between microRNAs and messenger RNAs, which affect numerous molecular pathways and physiological functions. Moreover, many disorders, including breast cancer, are associated with the dysregulation of microRNA. Sparingly, many microRNAs can suppress cancer cell proliferation, apoptosis, angiogenesis, invasion, metastasis, and vice versa. Remarkably, microRNAs can be harvested from patients' biofluids to predict disease progression that considered a non-invasive method. Nevertheless, MicroRNAs are currently utilized as anti- cancer therapies combined with other drug therapies or even as a single agents' treatment. Therefore, this review will focus on microRNAs' role in breast cancer as an indicator of disease progression. In addition, this review summarizes the current knowledge of drug sensitivity and methods in detecting microRNA and their application to improve patient care and identifies the current gaps in this field." @default.
- W3208380091 created "2021-11-08" @default.
- W3208380091 creator A5015657393 @default.
- W3208380091 date "2021-10-25" @default.
- W3208380091 modified "2023-09-26" @default.
- W3208380091 title "MicroRNAs Role in Breast Cancer: Theranostic Application in Saudi Arabia" @default.
- W3208380091 cites W144423133 @default.
- W3208380091 cites W1533422205 @default.
- W3208380091 cites W1611419331 @default.
- W3208380091 cites W1647075334 @default.
- W3208380091 cites W1765595419 @default.
- W3208380091 cites W1920303762 @default.
- W3208380091 cites W1936353033 @default.
- W3208380091 cites W1967342065 @default.
- W3208380091 cites W1970094205 @default.
- W3208380091 cites W1970121668 @default.
- W3208380091 cites W1973144992 @default.
- W3208380091 cites W1973421470 @default.
- W3208380091 cites W1973903209 @default.
- W3208380091 cites W1989057528 @default.
- W3208380091 cites W1989706089 @default.
- W3208380091 cites W1994455902 @default.
- W3208380091 cites W1999746344 @default.
- W3208380091 cites W2002061154 @default.
- W3208380091 cites W2005894707 @default.
- W3208380091 cites W2006173503 @default.
- W3208380091 cites W2006247279 @default.
- W3208380091 cites W2024544530 @default.
- W3208380091 cites W2026570544 @default.
- W3208380091 cites W2030658020 @default.
- W3208380091 cites W2034269086 @default.
- W3208380091 cites W2047455573 @default.
- W3208380091 cites W2047529648 @default.
- W3208380091 cites W2049982543 @default.
- W3208380091 cites W2050819284 @default.
- W3208380091 cites W2051599263 @default.
- W3208380091 cites W2065121565 @default.
- W3208380091 cites W2067913353 @default.
- W3208380091 cites W2074664629 @default.
- W3208380091 cites W2077393126 @default.
- W3208380091 cites W2085220756 @default.
- W3208380091 cites W2085570374 @default.
- W3208380091 cites W2090049175 @default.
- W3208380091 cites W2091344124 @default.
- W3208380091 cites W2092049057 @default.
- W3208380091 cites W2093905827 @default.
- W3208380091 cites W2099384129 @default.
- W3208380091 cites W2099446302 @default.
- W3208380091 cites W2100932663 @default.
- W3208380091 cites W2103052577 @default.
- W3208380091 cites W2116071996 @default.
- W3208380091 cites W2116743772 @default.
- W3208380091 cites W2118742153 @default.
- W3208380091 cites W2119604948 @default.
- W3208380091 cites W2126336279 @default.
- W3208380091 cites W2129355962 @default.
- W3208380091 cites W2131596261 @default.
- W3208380091 cites W2132015542 @default.
- W3208380091 cites W2135314242 @default.
- W3208380091 cites W2137881107 @default.
- W3208380091 cites W2137999492 @default.
- W3208380091 cites W2138664009 @default.
- W3208380091 cites W2139242035 @default.
- W3208380091 cites W2139273728 @default.
- W3208380091 cites W2139342290 @default.
- W3208380091 cites W2144038313 @default.
- W3208380091 cites W2153961241 @default.
- W3208380091 cites W2156323704 @default.
- W3208380091 cites W2159627472 @default.
- W3208380091 cites W2159807040 @default.
- W3208380091 cites W2160467221 @default.
- W3208380091 cites W2160968516 @default.
- W3208380091 cites W2161782613 @default.
- W3208380091 cites W2163145740 @default.
- W3208380091 cites W2163199119 @default.
- W3208380091 cites W2163881785 @default.
- W3208380091 cites W2168362647 @default.
- W3208380091 cites W2170647698 @default.
- W3208380091 cites W2170740525 @default.
- W3208380091 cites W2251277318 @default.
- W3208380091 cites W2259938310 @default.
- W3208380091 cites W2302777414 @default.
- W3208380091 cites W2396745650 @default.
- W3208380091 cites W2507227771 @default.
- W3208380091 cites W2509815162 @default.
- W3208380091 cites W2511509572 @default.
- W3208380091 cites W2516445915 @default.
- W3208380091 cites W2521569068 @default.
- W3208380091 cites W2548429415 @default.
- W3208380091 cites W2583563217 @default.
- W3208380091 cites W2586688899 @default.
- W3208380091 cites W2593488635 @default.
- W3208380091 cites W2617395622 @default.
- W3208380091 cites W2735645704 @default.
- W3208380091 cites W2751143162 @default.
- W3208380091 cites W2753109313 @default.
- W3208380091 cites W2763422050 @default.
- W3208380091 cites W2768169798 @default.
- W3208380091 cites W2774609542 @default.
- W3208380091 cites W2790289424 @default.