Matches in SemOpenAlex for { <https://semopenalex.org/work/W3208382920> ?p ?o ?g. }
Showing items 1 to 85 of
85
with 100 items per page.
- W3208382920 endingPage "52" @default.
- W3208382920 startingPage "48" @default.
- W3208382920 abstract "National UK guidelines suggest that axillary lymph node dissection (ALND) is no longer mandatory for selected early node-positive breast cancer patients. Our study aimed to identify patients with early breast cancer and ultrasound (USS)-positive axillary metastasis who possess low burden of axillary disease and can avoid ALND.We conducted a 5-year study of prospectively collected data of patients with clinically T1-2, N0 breast cancer and a positive USS-guided axillary biopsy. Primary outcome was involvement of 1-2 lymph nodes (low disease burden) or ≥3 lymph nodes (higher axillary disease) on final ALND histology. Tumour type, size, grade, multifocality, receptor status, number of abnormal imaged nodes and presence of lympho-vascular invasion (LVI) were recorded. Data were analysed using chi-squared and Student's t-test.One hundred and sixty-six patients underwent ALND for pT1-2 breast cancer. Seventy patients had no clinically palpable lymphadenopathy but a positive USS-guided biopsy. Of 70 patients, 32 women (46%) had low disease burden, whereas 38 women (54%) had higher axillary disease in final histology. LVI and >1 abnormal lymph node on USS were both significantly associated with higher disease burden (p = 0.050 and 0.009, respectively).Our study confirms the presence of an important patient cohort, who are clinically node-negative with a positive USS-guided biopsy and a low volume of axillary disease. No imaging modality currently has the accuracy required to identify patients with this low disease burden preoperatively but we propose a simple algorithm for axillary management in this subgroup." @default.
- W3208382920 created "2021-11-08" @default.
- W3208382920 creator A5021523393 @default.
- W3208382920 creator A5045676719 @default.
- W3208382920 creator A5063605014 @default.
- W3208382920 creator A5081485324 @default.
- W3208382920 date "2022-01-01" @default.
- W3208382920 modified "2023-09-24" @default.
- W3208382920 title "Ultrasound-positive axillary lymph nodes in early breast cancer: can a patient subgroup avoid axillary lymph node dissection? A simple algorithm is suggested" @default.
- W3208382920 cites W1979974409 @default.
- W3208382920 cites W2012202415 @default.
- W3208382920 cites W2020321814 @default.
- W3208382920 cites W2070281077 @default.
- W3208382920 cites W2106779008 @default.
- W3208382920 cites W2115527491 @default.
- W3208382920 cites W2119434761 @default.
- W3208382920 cites W2133865595 @default.
- W3208382920 cites W2134538885 @default.
- W3208382920 cites W2142059226 @default.
- W3208382920 cites W2172114428 @default.
- W3208382920 cites W2261250208 @default.
- W3208382920 cites W2740772745 @default.
- W3208382920 cites W2952448682 @default.
- W3208382920 cites W3214787579 @default.
- W3208382920 doi "https://doi.org/10.1308/rcsann.2020.7122" @default.
- W3208382920 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/34730418" @default.
- W3208382920 hasPublicationYear "2022" @default.
- W3208382920 type Work @default.
- W3208382920 sameAs 3208382920 @default.
- W3208382920 citedByCount "0" @default.
- W3208382920 crossrefType "journal-article" @default.
- W3208382920 hasAuthorship W3208382920A5021523393 @default.
- W3208382920 hasAuthorship W3208382920A5045676719 @default.
- W3208382920 hasAuthorship W3208382920A5063605014 @default.
- W3208382920 hasAuthorship W3208382920A5081485324 @default.
- W3208382920 hasConcept C121608353 @default.
- W3208382920 hasConcept C126322002 @default.
- W3208382920 hasConcept C126838900 @default.
- W3208382920 hasConcept C141071460 @default.
- W3208382920 hasConcept C142724271 @default.
- W3208382920 hasConcept C2775934546 @default.
- W3208382920 hasConcept C2776608951 @default.
- W3208382920 hasConcept C2777649267 @default.
- W3208382920 hasConcept C2779720271 @default.
- W3208382920 hasConcept C2780212769 @default.
- W3208382920 hasConcept C2780849966 @default.
- W3208382920 hasConcept C2908949552 @default.
- W3208382920 hasConcept C530470458 @default.
- W3208382920 hasConcept C71924100 @default.
- W3208382920 hasConceptScore W3208382920C121608353 @default.
- W3208382920 hasConceptScore W3208382920C126322002 @default.
- W3208382920 hasConceptScore W3208382920C126838900 @default.
- W3208382920 hasConceptScore W3208382920C141071460 @default.
- W3208382920 hasConceptScore W3208382920C142724271 @default.
- W3208382920 hasConceptScore W3208382920C2775934546 @default.
- W3208382920 hasConceptScore W3208382920C2776608951 @default.
- W3208382920 hasConceptScore W3208382920C2777649267 @default.
- W3208382920 hasConceptScore W3208382920C2779720271 @default.
- W3208382920 hasConceptScore W3208382920C2780212769 @default.
- W3208382920 hasConceptScore W3208382920C2780849966 @default.
- W3208382920 hasConceptScore W3208382920C2908949552 @default.
- W3208382920 hasConceptScore W3208382920C530470458 @default.
- W3208382920 hasConceptScore W3208382920C71924100 @default.
- W3208382920 hasIssue "1" @default.
- W3208382920 hasLocation W32083829201 @default.
- W3208382920 hasLocation W32083829202 @default.
- W3208382920 hasOpenAccess W3208382920 @default.
- W3208382920 hasPrimaryLocation W32083829201 @default.
- W3208382920 hasRelatedWork W1966886751 @default.
- W3208382920 hasRelatedWork W2042915415 @default.
- W3208382920 hasRelatedWork W2078754810 @default.
- W3208382920 hasRelatedWork W2339834749 @default.
- W3208382920 hasRelatedWork W2384408757 @default.
- W3208382920 hasRelatedWork W2410018501 @default.
- W3208382920 hasRelatedWork W2899858984 @default.
- W3208382920 hasRelatedWork W2914749537 @default.
- W3208382920 hasRelatedWork W4236130971 @default.
- W3208382920 hasRelatedWork W4323544746 @default.
- W3208382920 hasVolume "104" @default.
- W3208382920 isParatext "false" @default.
- W3208382920 isRetracted "false" @default.
- W3208382920 magId "3208382920" @default.
- W3208382920 workType "article" @default.