Matches in SemOpenAlex for { <https://semopenalex.org/work/W3208436697> ?p ?o ?g. }
Showing items 1 to 86 of
86
with 100 items per page.
- W3208436697 abstract "Cardiovascular diseases are the leading causes of deaths despite several advancements in the current medical interventions. Among them, myocardial infarction (MI) is the most alarming disease as about 17.1 million peoples die every year due to MI.The present study was designed to investigate the potential cardioprotective effect of combination of standardized extracts of Tinospora cordifolia (SETC) (250 mg/kg and 500 mg/kg) and Ocimum sanctum (SEOS) (50 mg/kg) in isoproterenol (ISO)-induced MI.MI was induced in rats by subcutaneous injection of ISO for 2 consecutive days at an interval of 24 h. Rats were pretreated with test drugs for the period of 21 days, and ISO was administered on the 20th and 21st days. At the end of experiment, i.e., on 22nd-day electrocardiograph, a hemodynamic, biochemical, and histopathological study of heart tissues was evaluated from control and experimental groups and statistically analyzed by one-way analysis of variance followed by Tukey's test.ISO-administered rats showed significant changes in electrocardiograph, mean arterial blood pressure, heart rate, biochemical markers, antioxidant parameters, and histopathology of heart. The activities of cardiac biomarkers were reduced in serum, and there was an increase in antioxidants in heart tissue of test drug-treated animals. Similarly, electrocardiograph, mean arterial blood pressure, and heart rate were restored to normalcy in all test and standard drug-treated animals.The SETC 500 mg/kg in combination with SEOS 50 mg/kg was found to be effective in prevention of myocardial injury induced by ISO." @default.
- W3208436697 created "2021-11-08" @default.
- W3208436697 creator A5024584012 @default.
- W3208436697 creator A5024691283 @default.
- W3208436697 creator A5032412684 @default.
- W3208436697 creator A5040329164 @default.
- W3208436697 creator A5061813218 @default.
- W3208436697 creator A5075253496 @default.
- W3208436697 date "2020-01-01" @default.
- W3208436697 modified "2023-10-05" @default.
- W3208436697 title "Pharmacodynamic interaction of Tinospora cordifolia Willd. With Ocimum sanctum Linn. in isoproterenol-induced cardiac toxicity" @default.
- W3208436697 cites W1499704472 @default.
- W3208436697 cites W1530078623 @default.
- W3208436697 cites W1637175425 @default.
- W3208436697 cites W1898678962 @default.
- W3208436697 cites W1993873667 @default.
- W3208436697 cites W1994323315 @default.
- W3208436697 cites W2006370393 @default.
- W3208436697 cites W2027502568 @default.
- W3208436697 cites W203326366 @default.
- W3208436697 cites W2061913723 @default.
- W3208436697 cites W2089385534 @default.
- W3208436697 cites W2091875032 @default.
- W3208436697 cites W2100943789 @default.
- W3208436697 cites W2106023455 @default.
- W3208436697 cites W2113824360 @default.
- W3208436697 cites W2145697942 @default.
- W3208436697 cites W2298419517 @default.
- W3208436697 cites W2411047947 @default.
- W3208436697 cites W2412825700 @default.
- W3208436697 cites W2568546426 @default.
- W3208436697 doi "https://doi.org/10.4103/ayu.ayu_127_19" @default.
- W3208436697 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/34908798" @default.
- W3208436697 hasPublicationYear "2020" @default.
- W3208436697 type Work @default.
- W3208436697 sameAs 3208436697 @default.
- W3208436697 citedByCount "0" @default.
- W3208436697 crossrefType "journal-article" @default.
- W3208436697 hasAuthorship W3208436697A5024584012 @default.
- W3208436697 hasAuthorship W3208436697A5024691283 @default.
- W3208436697 hasAuthorship W3208436697A5032412684 @default.
- W3208436697 hasAuthorship W3208436697A5040329164 @default.
- W3208436697 hasAuthorship W3208436697A5061813218 @default.
- W3208436697 hasAuthorship W3208436697A5075253496 @default.
- W3208436697 hasBestOaLocation W32084366972 @default.
- W3208436697 hasConcept C126322002 @default.
- W3208436697 hasConcept C164705383 @default.
- W3208436697 hasConcept C2777953023 @default.
- W3208436697 hasConcept C2778523797 @default.
- W3208436697 hasConcept C2779342943 @default.
- W3208436697 hasConcept C42219234 @default.
- W3208436697 hasConcept C500558357 @default.
- W3208436697 hasConcept C556039675 @default.
- W3208436697 hasConcept C71924100 @default.
- W3208436697 hasConcept C84393581 @default.
- W3208436697 hasConcept C98274493 @default.
- W3208436697 hasConceptScore W3208436697C126322002 @default.
- W3208436697 hasConceptScore W3208436697C164705383 @default.
- W3208436697 hasConceptScore W3208436697C2777953023 @default.
- W3208436697 hasConceptScore W3208436697C2778523797 @default.
- W3208436697 hasConceptScore W3208436697C2779342943 @default.
- W3208436697 hasConceptScore W3208436697C42219234 @default.
- W3208436697 hasConceptScore W3208436697C500558357 @default.
- W3208436697 hasConceptScore W3208436697C556039675 @default.
- W3208436697 hasConceptScore W3208436697C71924100 @default.
- W3208436697 hasConceptScore W3208436697C84393581 @default.
- W3208436697 hasConceptScore W3208436697C98274493 @default.
- W3208436697 hasLocation W32084366971 @default.
- W3208436697 hasLocation W32084366972 @default.
- W3208436697 hasLocation W32084366973 @default.
- W3208436697 hasOpenAccess W3208436697 @default.
- W3208436697 hasPrimaryLocation W32084366971 @default.
- W3208436697 hasRelatedWork W2000999406 @default.
- W3208436697 hasRelatedWork W2088253880 @default.
- W3208436697 hasRelatedWork W2099025649 @default.
- W3208436697 hasRelatedWork W2189134118 @default.
- W3208436697 hasRelatedWork W2904300493 @default.
- W3208436697 hasRelatedWork W2948587658 @default.
- W3208436697 hasRelatedWork W3009476082 @default.
- W3208436697 hasRelatedWork W3106602882 @default.
- W3208436697 hasRelatedWork W4231179304 @default.
- W3208436697 hasRelatedWork W2296145848 @default.
- W3208436697 isParatext "false" @default.
- W3208436697 isRetracted "false" @default.
- W3208436697 magId "3208436697" @default.
- W3208436697 workType "article" @default.