Matches in SemOpenAlex for { <https://semopenalex.org/work/W3208442617> ?p ?o ?g. }
Showing items 1 to 92 of
92
with 100 items per page.
- W3208442617 endingPage "4" @default.
- W3208442617 startingPage "1" @default.
- W3208442617 abstract "Hypoxemia and coagulopathy are common in severe symptomatic patients of coronavirus disease 2019 (COVID-19). Histological evidence shows implication of complement activation and lung injury. We prospectively research sign of complement activation and presence of thrombotic microangiopathy in 8 severe patients. Six of them presented moderate elevation of final pathway of complement –sC5b-9 (median value: 350 ng/mL [IQR: 300,5-514,95 ng/mL]). Two patients have been autopsied and presence of thrombotic microvascular injury has been found. Interestingly, none the 8 patients had signs of mechanical hemolytic anemia (median value of hemoglobin : 10,5 gr/dL[IQR : 8,1-11,9], median value of haptoglobuline 4,49 [IQR 3,55-4,66], none of the patients has schistocyte) and thrombocytopenia (median value: 348000/mL [IQR : 266 000-401 000). Finally, all 8 patients had elevated d-dimer (median value: 2226 μgr/l [IQR: 1493–2362]) and soluble fibrin monomer complex (median value: 8.5 mg/mL, IQR [<6–10.6]). In summary, this study show moderate activation of complement and coagulation with presence of thrombotic microvascular injury in patients with severe COVID-19 without evidence of systemic thrombotic microangiopathy." @default.
- W3208442617 created "2021-11-08" @default.
- W3208442617 creator A5006003007 @default.
- W3208442617 creator A5013398931 @default.
- W3208442617 creator A5025624026 @default.
- W3208442617 creator A5030226078 @default.
- W3208442617 creator A5035394236 @default.
- W3208442617 creator A5036461762 @default.
- W3208442617 creator A5053398750 @default.
- W3208442617 creator A5078872590 @default.
- W3208442617 creator A5087173123 @default.
- W3208442617 creator A5090720219 @default.
- W3208442617 date "2021-01-01" @default.
- W3208442617 modified "2023-10-03" @default.
- W3208442617 title "Thrombotic Microvascular Injury is not Mediated by Thrombotic Micro Angiopathy Despite Systemic Complement Activation in COVID-19 Patients" @default.
- W3208442617 cites W3007940623 @default.
- W3208442617 cites W3016123694 @default.
- W3208442617 doi "https://doi.org/10.35248/2155-9864.21.12.480" @default.
- W3208442617 hasPublicationYear "2021" @default.
- W3208442617 type Work @default.
- W3208442617 sameAs 3208442617 @default.
- W3208442617 citedByCount "0" @default.
- W3208442617 crossrefType "journal-article" @default.
- W3208442617 hasAuthorship W3208442617A5006003007 @default.
- W3208442617 hasAuthorship W3208442617A5013398931 @default.
- W3208442617 hasAuthorship W3208442617A5025624026 @default.
- W3208442617 hasAuthorship W3208442617A5030226078 @default.
- W3208442617 hasAuthorship W3208442617A5035394236 @default.
- W3208442617 hasAuthorship W3208442617A5036461762 @default.
- W3208442617 hasAuthorship W3208442617A5053398750 @default.
- W3208442617 hasAuthorship W3208442617A5078872590 @default.
- W3208442617 hasAuthorship W3208442617A5087173123 @default.
- W3208442617 hasAuthorship W3208442617A5090720219 @default.
- W3208442617 hasConcept C111684460 @default.
- W3208442617 hasConcept C126322002 @default.
- W3208442617 hasConcept C134018914 @default.
- W3208442617 hasConcept C159654299 @default.
- W3208442617 hasConcept C203014093 @default.
- W3208442617 hasConcept C2776513394 @default.
- W3208442617 hasConcept C2776779939 @default.
- W3208442617 hasConcept C2777878052 @default.
- W3208442617 hasConcept C2779134260 @default.
- W3208442617 hasConcept C2779519742 @default.
- W3208442617 hasConcept C2779936836 @default.
- W3208442617 hasConcept C555293320 @default.
- W3208442617 hasConcept C71924100 @default.
- W3208442617 hasConcept C90924648 @default.
- W3208442617 hasConceptScore W3208442617C111684460 @default.
- W3208442617 hasConceptScore W3208442617C126322002 @default.
- W3208442617 hasConceptScore W3208442617C134018914 @default.
- W3208442617 hasConceptScore W3208442617C159654299 @default.
- W3208442617 hasConceptScore W3208442617C203014093 @default.
- W3208442617 hasConceptScore W3208442617C2776513394 @default.
- W3208442617 hasConceptScore W3208442617C2776779939 @default.
- W3208442617 hasConceptScore W3208442617C2777878052 @default.
- W3208442617 hasConceptScore W3208442617C2779134260 @default.
- W3208442617 hasConceptScore W3208442617C2779519742 @default.
- W3208442617 hasConceptScore W3208442617C2779936836 @default.
- W3208442617 hasConceptScore W3208442617C555293320 @default.
- W3208442617 hasConceptScore W3208442617C71924100 @default.
- W3208442617 hasConceptScore W3208442617C90924648 @default.
- W3208442617 hasIssue "8" @default.
- W3208442617 hasLocation W32084426171 @default.
- W3208442617 hasOpenAccess W3208442617 @default.
- W3208442617 hasPrimaryLocation W32084426171 @default.
- W3208442617 hasRelatedWork W153925048 @default.
- W3208442617 hasRelatedWork W1951908718 @default.
- W3208442617 hasRelatedWork W1987946003 @default.
- W3208442617 hasRelatedWork W1997218725 @default.
- W3208442617 hasRelatedWork W2041985620 @default.
- W3208442617 hasRelatedWork W2414516233 @default.
- W3208442617 hasRelatedWork W2546773282 @default.
- W3208442617 hasRelatedWork W2557318166 @default.
- W3208442617 hasRelatedWork W2560631272 @default.
- W3208442617 hasRelatedWork W2576916228 @default.
- W3208442617 hasRelatedWork W2596520060 @default.
- W3208442617 hasRelatedWork W2792864982 @default.
- W3208442617 hasRelatedWork W2979380947 @default.
- W3208442617 hasRelatedWork W3027784163 @default.
- W3208442617 hasRelatedWork W3036566648 @default.
- W3208442617 hasRelatedWork W3094458856 @default.
- W3208442617 hasRelatedWork W3097538337 @default.
- W3208442617 hasRelatedWork W3115979761 @default.
- W3208442617 hasRelatedWork W3158510934 @default.
- W3208442617 hasRelatedWork W3207481942 @default.
- W3208442617 hasVolume "12" @default.
- W3208442617 isParatext "false" @default.
- W3208442617 isRetracted "false" @default.
- W3208442617 magId "3208442617" @default.
- W3208442617 workType "article" @default.