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- W3208484605 abstract "Hyperectumine (1), the first C19 benzylisoquinoline alkaloid with a complicated ring system, was isolated from Hypecoum erectum and structurally characterized. Its biosynthetic origin should involve a hybrid pattern of C8 + C8 + C1 + C2, from which a C17 benzylisoquinoline alkaloid might be further attacked by a malonamic acid and undergo decarboxylation and cyclization to produce 1. Compound (-)-1 exhibited moderate anti-inflammatory activity via suppression of LPS-activated inflammatory mediators in RAW 264.7 macrophage cells." @default.
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- W3208484605 date "2021-11-01" @default.
- W3208484605 modified "2023-10-01" @default.
- W3208484605 title "C<sub>19</sub> Benzylisoquinoline Alkaloid with Unprecedented Architecture from <i>Hypecoum erectum</i>" @default.
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- W3208484605 doi "https://doi.org/10.1021/acs.joc.1c01990" @default.
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