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- W3208519957 abstract "Recent advances in nano/microfluidics have led to the miniaturization of surface-based chemical and biochemical sensors, with applications ranging from environmental monitoring to disease diagnostics. These systems rely on the detection of analytes flowing in a liquid sample, by exploiting their innate nature to react with specific receptors immobilized on the microchannel walls. The efficiency of these systems is defined by the cumulative effect of analyte detection speed, sensitivity, and specificity. In this perspective, we provide a fresh outlook on the use of important parameters obtained from well-characterized analytical models, by connecting the mass transport and reaction limits with the experimentally attainable limits of analyte detection efficiency. Specifically, we breakdown when and how the operational (e.g., flow rates, channel geometries, mode of detection, etc.) and molecular (e.g., receptor affinity and functionality) variables can be tailored to enhance the analyte detection time, analytical specificity, and sensitivity of the system (i.e., limit of detection). Finally, we present a simple yet cohesive blueprint for the development of high-efficiency surface-based microfluidic sensors for rapid, sensitive, and specific detection of chemical and biochemical analytes, pertinent to a variety of applications." @default.
- W3208519957 created "2021-11-08" @default.
- W3208519957 creator A5033494285 @default.
- W3208519957 creator A5080461678 @default.
- W3208519957 date "2021-09-22" @default.
- W3208519957 modified "2023-10-16" @default.
- W3208519957 title "Toward the Development of Rapid, Specific, and Sensitive Microfluidic Sensors: A Comprehensive Device Blueprint" @default.
- W3208519957 cites W1552643586 @default.
- W3208519957 cites W1568084954 @default.
- W3208519957 cites W1812416290 @default.
- W3208519957 cites W1816090072 @default.
- W3208519957 cites W1932716429 @default.
- W3208519957 cites W1966584585 @default.
- W3208519957 cites W1972340795 @default.
- W3208519957 cites W1973013997 @default.
- W3208519957 cites W1981672133 @default.
- W3208519957 cites W1983416604 @default.
- W3208519957 cites W1988633531 @default.
- W3208519957 cites W1989685292 @default.
- W3208519957 cites W1989900757 @default.
- W3208519957 cites W1990386101 @default.
- W3208519957 cites W1991013335 @default.
- W3208519957 cites W1991635370 @default.
- W3208519957 cites W1993363985 @default.
- W3208519957 cites W1993475070 @default.
- W3208519957 cites W1999460433 @default.
- W3208519957 cites W2001607419 @default.
- W3208519957 cites W2001810767 @default.
- W3208519957 cites W2001927093 @default.
- W3208519957 cites W2001990899 @default.
- W3208519957 cites W2003024465 @default.
- W3208519957 cites W2004239476 @default.
- W3208519957 cites W2008812397 @default.
- W3208519957 cites W2012746817 @default.
- W3208519957 cites W2013025233 @default.
- W3208519957 cites W2016791086 @default.
- W3208519957 cites W2017147837 @default.
- W3208519957 cites W2020939327 @default.
- W3208519957 cites W2024703652 @default.
- W3208519957 cites W2027138941 @default.
- W3208519957 cites W2028021654 @default.
- W3208519957 cites W2029270424 @default.
- W3208519957 cites W2030561313 @default.
- W3208519957 cites W2032736963 @default.
- W3208519957 cites W2032773211 @default.
- W3208519957 cites W2033941322 @default.
- W3208519957 cites W2036433385 @default.
- W3208519957 cites W2039074967 @default.
- W3208519957 cites W2041989691 @default.
- W3208519957 cites W2048240071 @default.
- W3208519957 cites W2048931583 @default.
- W3208519957 cites W2050577542 @default.
- W3208519957 cites W2052059475 @default.
- W3208519957 cites W2052489824 @default.
- W3208519957 cites W2056066120 @default.
- W3208519957 cites W2057598616 @default.
- W3208519957 cites W2058764403 @default.
- W3208519957 cites W2059064270 @default.
- W3208519957 cites W2059579642 @default.
- W3208519957 cites W2062259126 @default.
- W3208519957 cites W2062288737 @default.
- W3208519957 cites W2069542174 @default.
- W3208519957 cites W2069648588 @default.
- W3208519957 cites W2069742881 @default.
- W3208519957 cites W2072679798 @default.
- W3208519957 cites W2076873445 @default.
- W3208519957 cites W2077801714 @default.
- W3208519957 cites W2078363942 @default.
- W3208519957 cites W2082891648 @default.
- W3208519957 cites W2085553278 @default.
- W3208519957 cites W2087897259 @default.
- W3208519957 cites W2104262795 @default.
- W3208519957 cites W2109311842 @default.
- W3208519957 cites W2109485720 @default.
- W3208519957 cites W2115910755 @default.
- W3208519957 cites W2120098092 @default.
- W3208519957 cites W2127458256 @default.
- W3208519957 cites W2127653619 @default.
- W3208519957 cites W2129916165 @default.
- W3208519957 cites W2132067312 @default.
- W3208519957 cites W2133282256 @default.
- W3208519957 cites W2133930954 @default.
- W3208519957 cites W2139289380 @default.
- W3208519957 cites W2149292906 @default.
- W3208519957 cites W2150364024 @default.
- W3208519957 cites W2150605180 @default.
- W3208519957 cites W2156722900 @default.
- W3208519957 cites W2169575779 @default.
- W3208519957 cites W2171110640 @default.
- W3208519957 cites W2211395818 @default.
- W3208519957 cites W2235846674 @default.
- W3208519957 cites W2259788764 @default.
- W3208519957 cites W2264989853 @default.
- W3208519957 cites W2281938696 @default.
- W3208519957 cites W2295996937 @default.
- W3208519957 cites W2319553418 @default.
- W3208519957 cites W2320427261 @default.
- W3208519957 cites W2321334902 @default.