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• W3208601971 abstract "Pollinators, particularly wild bees, are suffering declines across the globe, and pesticides are thought to be drivers of these declines. Research into, and regulation of pesticides has focused on the active ingredients, and their impact on bee health. In contrast, the additional components in pesticide formulations have been overlooked as potential threats. By testing an acute oral dose of the fungicide product Amistar, and equivalent doses of each individual co-formulant, we were able to measure the toxicity of the formulation and identify the ingredient responsible. We found that a co-formulant, alcohol ethoxylates, caused a range of damage to bumble bee health. Exposure to alcohol ethoxylates caused 30% mortality and a range of sublethal effects. Alcohol ethoxylates treated bees consumed half as much sucrose as negative control bees over the course of the experiment and lost weight. Alcohol ethoxylates treated bees had significant melanisation of their midguts, evidence of gut damage. We suggest that this gut damage explains the reduction in appetite, weight loss and mortality, with bees dying from energy depletion. Our results demonstrate that sublethal impacts of pesticide formulations need to be considered during regulatory consideration, and that co-formulants can be more toxic than active ingredients." @default.
• W3208601971 created "2021-11-08" @default.
• W3208601971 creator A5014627135 @default.
• W3208601971 creator A5018511161 @default.
• W3208601971 date "2021-11-05" @default.
• W3208601971 modified "2023-10-04" @default.
• W3208601971 title "Co-formulant in a commercial fungicide product causes lethal and sub-lethal effects in bumble bees" @default.
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• W3208601971 doi "https://doi.org/10.1038/s41598-021-00919-x" @default.
• W3208601971 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/8571393" @default.
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• W3208601971 hasPublicationYear "2021" @default.
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