Matches in SemOpenAlex for { <https://semopenalex.org/work/W3208654042> ?p ?o ?g. }
- W3208654042 abstract "Abstract Background The gut microbiome is the totality of microorganisms, bacteria, viruses, protozoa, and fungi within the gastrointestinal tract. The gut microbiome plays key roles in various physiological and pathological processes through regulating varieties of metabolic factors such as short-chain fatty acids, bile acids and amino acids. Nuclear receptors, as metabolic mediators, act as a series of intermediates between the microbiome and the host and help the microbiome regulate diverse processes in the host. Recently, nuclear receptors such as farnesoid X receptor, peroxisome proliferator-activated receptors, aryl hydrocarbon receptor and vitamin D receptor have been identified as key regulators of the microbiome-host crosstalk. These nuclear receptors regulate metabolic processes, immune activity, autophagy, non-alcoholic and alcoholic fatty liver disease, inflammatory bowel disease, cancer, obesity, and type-2 diabetes. Conclusion In this review, we have summarized the functions of the nuclear receptors in the gut microbiome-host axis in different physiological and pathological conditions, indicating that the nuclear receptors may be the good targets for treatment of different diseases through the crosstalk with the gut microbiome." @default.
- W3208654042 created "2021-11-08" @default.
- W3208654042 creator A5024584263 @default.
- W3208654042 creator A5047152293 @default.
- W3208654042 creator A5049907847 @default.
- W3208654042 date "2021-11-05" @default.
- W3208654042 modified "2023-10-17" @default.
- W3208654042 title "Nuclear receptors: a bridge linking the gut microbiome and the host" @default.
- W3208654042 cites W1483367799 @default.
- W3208654042 cites W1513061804 @default.
- W3208654042 cites W1551488257 @default.
- W3208654042 cites W1574819711 @default.
- W3208654042 cites W1593793946 @default.
- W3208654042 cites W1665140791 @default.
- W3208654042 cites W1673053485 @default.
- W3208654042 cites W1827069369 @default.
- W3208654042 cites W1894632157 @default.
- W3208654042 cites W1932980005 @default.
- W3208654042 cites W1963587340 @default.
- W3208654042 cites W1966584131 @default.
- W3208654042 cites W1968928885 @default.
- W3208654042 cites W1969721624 @default.
- W3208654042 cites W1970618014 @default.
- W3208654042 cites W1976621716 @default.
- W3208654042 cites W1980914602 @default.
- W3208654042 cites W1983204866 @default.
- W3208654042 cites W1996613294 @default.
- W3208654042 cites W2021998283 @default.
- W3208654042 cites W2024956244 @default.
- W3208654042 cites W2032872823 @default.
- W3208654042 cites W2033204507 @default.
- W3208654042 cites W2041747019 @default.
- W3208654042 cites W2043131385 @default.
- W3208654042 cites W2044216294 @default.
- W3208654042 cites W2053581007 @default.
- W3208654042 cites W2065147071 @default.
- W3208654042 cites W2066092624 @default.
- W3208654042 cites W2073578030 @default.
- W3208654042 cites W2076452736 @default.
- W3208654042 cites W2079080809 @default.
- W3208654042 cites W2082184791 @default.
- W3208654042 cites W2085847834 @default.
- W3208654042 cites W2086410640 @default.
- W3208654042 cites W2103038927 @default.
- W3208654042 cites W2107051699 @default.
- W3208654042 cites W2122860085 @default.
- W3208654042 cites W2124025733 @default.
- W3208654042 cites W2124210208 @default.
- W3208654042 cites W2134058536 @default.
- W3208654042 cites W2134897177 @default.
- W3208654042 cites W2142626121 @default.
- W3208654042 cites W2149515881 @default.
- W3208654042 cites W2152691788 @default.
- W3208654042 cites W2152714616 @default.
- W3208654042 cites W2156494960 @default.
- W3208654042 cites W2167120766 @default.
- W3208654042 cites W2167628071 @default.
- W3208654042 cites W2231949068 @default.
- W3208654042 cites W2293546533 @default.
- W3208654042 cites W2328023807 @default.
- W3208654042 cites W2343917624 @default.
- W3208654042 cites W2344941018 @default.
- W3208654042 cites W2345604850 @default.
- W3208654042 cites W2346722402 @default.
- W3208654042 cites W2346752870 @default.
- W3208654042 cites W2395806598 @default.
- W3208654042 cites W2416624599 @default.
- W3208654042 cites W2417065626 @default.
- W3208654042 cites W2428595929 @default.
- W3208654042 cites W2460141262 @default.
- W3208654042 cites W2519008943 @default.
- W3208654042 cites W2531570974 @default.
- W3208654042 cites W2533013551 @default.
- W3208654042 cites W2546420937 @default.
- W3208654042 cites W2555845667 @default.
- W3208654042 cites W2559255592 @default.
- W3208654042 cites W2560750456 @default.
- W3208654042 cites W2566365785 @default.
- W3208654042 cites W2591336302 @default.
- W3208654042 cites W2593883051 @default.
- W3208654042 cites W2593963627 @default.
- W3208654042 cites W2598803157 @default.
- W3208654042 cites W2604966191 @default.
- W3208654042 cites W2605955022 @default.
- W3208654042 cites W2607504605 @default.
- W3208654042 cites W2617311130 @default.
- W3208654042 cites W2728822570 @default.
- W3208654042 cites W2737961213 @default.
- W3208654042 cites W2743073899 @default.
- W3208654042 cites W2753988219 @default.
- W3208654042 cites W2754032461 @default.
- W3208654042 cites W2767436653 @default.
- W3208654042 cites W2773928224 @default.
- W3208654042 cites W2774287749 @default.
- W3208654042 cites W2776695687 @default.
- W3208654042 cites W2782850680 @default.
- W3208654042 cites W2783048272 @default.
- W3208654042 cites W2784137104 @default.
- W3208654042 cites W2789495752 @default.
- W3208654042 cites W2791904618 @default.