FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W3208666404> ?p ?o ?g. }

• W3208666404 endingPage "113967" @default.
• W3208666404 startingPage "113967" @default.
• W3208666404 abstract "Indoleamine 2,3-dioxygenase 1 (IDO1), a known immunosuppressive enzyme that catalyzes the rate-limiting step in the oxidation of tryptophan (Trp) to kynurenine (Kyn), has received increasing attention as an attractive immunotherapeutic target for cancer therapy. Up to now, eleven small-molecule IDO1 inhibitors have entered clinical trials for the treatment of cancers. In addition, proteolysis targeting chimera (PROTAC) based degraders also provide prospects for cancer therapy. Herein we present a comprehensive overview of the medicinal chemistry strategies and potential therapeutic applications of IDO1 inhibitors in nonclinical trials and IDO1-PROTAC degraders." @default.
• W3208666404 created "2021-11-08" @default.
• W3208666404 creator A5040808710 @default.
• W3208666404 creator A5054180910 @default.
• W3208666404 creator A5056168495 @default.
• W3208666404 creator A5064708150 @default.
• W3208666404 date "2022-01-01" @default.
• W3208666404 modified "2023-10-15" @default.
• W3208666404 title "Indoleamine 2,3-dioxygenase 1 (IDO1) inhibitors and PROTAC-based degraders for cancer therapy" @default.
• W3208666404 cites W1487436709 @default.
• W3208666404 cites W1545334093 @default.
• W3208666404 cites W1607682771 @default.
• W3208666404 cites W18268914 @default.
• W3208666404 cites W1838472703 @default.
• W3208666404 cites W1972629684 @default.
• W3208666404 cites W1980907312 @default.
• W3208666404 cites W1983752910 @default.
• W3208666404 cites W1991295852 @default.
• W3208666404 cites W1997582687 @default.
• W3208666404 cites W2007316487 @default.
• W3208666404 cites W2007489575 @default.
• W3208666404 cites W2010343273 @default.
• W3208666404 cites W2014770478 @default.
• W3208666404 cites W2015933085 @default.
• W3208666404 cites W2017371906 @default.
• W3208666404 cites W2022430924 @default.
• W3208666404 cites W2024000351 @default.
• W3208666404 cites W2026429388 @default.
• W3208666404 cites W2043390055 @default.
• W3208666404 cites W2056989665 @default.
• W3208666404 cites W2080715471 @default.
• W3208666404 cites W2090410108 @default.
• W3208666404 cites W2092868813 @default.
• W3208666404 cites W2107429737 @default.
• W3208666404 cites W2111769244 @default.
• W3208666404 cites W2237051895 @default.
• W3208666404 cites W2314750720 @default.
• W3208666404 cites W2316238973 @default.
• W3208666404 cites W2331353920 @default.
• W3208666404 cites W2416156085 @default.
• W3208666404 cites W2516371018 @default.
• W3208666404 cites W2528974721 @default.
• W3208666404 cites W2529031177 @default.
• W3208666404 cites W2566719694 @default.
• W3208666404 cites W2587048937 @default.
• W3208666404 cites W2594368015 @default.
• W3208666404 cites W2612649234 @default.
• W3208666404 cites W2663049097 @default.
• W3208666404 cites W2739132742 @default.
• W3208666404 cites W2760912740 @default.
• W3208666404 cites W2770834155 @default.
• W3208666404 cites W2771972526 @default.
• W3208666404 cites W2784255252 @default.
• W3208666404 cites W2784283849 @default.
• W3208666404 cites W2790690876 @default.
• W3208666404 cites W2792931335 @default.
• W3208666404 cites W2800703793 @default.
• W3208666404 cites W2802137539 @default.
• W3208666404 cites W2807728333 @default.
• W3208666404 cites W2891880652 @default.
• W3208666404 cites W2902185751 @default.
• W3208666404 cites W2911609542 @default.
• W3208666404 cites W2912181843 @default.
• W3208666404 cites W2912593557 @default.
• W3208666404 cites W2913907509 @default.
• W3208666404 cites W2913920462 @default.
• W3208666404 cites W2942726985 @default.
• W3208666404 cites W2948871819 @default.
• W3208666404 cites W2949375297 @default.
• W3208666404 cites W2950606879 @default.
• W3208666404 cites W2951329663 @default.
• W3208666404 cites W2961331837 @default.
• W3208666404 cites W2963903120 @default.
• W3208666404 cites W2965080210 @default.
• W3208666404 cites W2967217932 @default.
• W3208666404 cites W2968627491 @default.
• W3208666404 cites W2973871636 @default.
• W3208666404 cites W2993145096 @default.
• W3208666404 cites W2999589361 @default.
• W3208666404 cites W3000339487 @default.
• W3208666404 cites W3008582994 @default.
• W3208666404 cites W3009333975 @default.
• W3208666404 cites W3010320410 @default.
• W3208666404 cites W3012367127 @default.
• W3208666404 cites W3015860015 @default.
• W3208666404 cites W3023756610 @default.
• W3208666404 cites W3029876968 @default.
• W3208666404 cites W3049724121 @default.
• W3208666404 cites W3097607229 @default.
• W3208666404 cites W3154612073 @default.
• W3208666404 cites W4233182411 @default.
• W3208666404 doi "https://doi.org/10.1016/j.ejmech.2021.113967" @default.
• W3208666404 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/34752953" @default.
• W3208666404 hasPublicationYear "2022" @default.
• W3208666404 type Work @default.
• W3208666404 sameAs 3208666404 @default.
• W3208666404 citedByCount "5" @default.
• W3208666404 countsByYear W32086664042022 @default.

• next