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- W3208687562 abstract "The last decade has witnessed the altered expression levels of long non-coding RNA HEIH in different types of cancer. More than half of the HEIH studies in cancer have been published within the last two years. To our knowledge, this is the first review to discuss very recent developments and insights into HEIH contribution to carcinogenesis. The functional role, molecular mechanism, and clinical significance of HEIH in human cancers are described in detail. The expression of HEIH is elevated in a broad spectrum of cancers, and its disorder contributes to cell proliferation, migration, invasion, and drug resistance of cancer cells through different underlying mechanisms. In addition, the high expression of HEIH is significantly associated with advanced tumor stage, tumor size and decreased overall survival, suggesting HEIH may function as a prognostic biomarker and potential therapeutic target for human cancers." @default.
- W3208687562 created "2021-11-08" @default.
- W3208687562 creator A5056573583 @default.
- W3208687562 creator A5075615304 @default.
- W3208687562 date "2021-10-24" @default.
- W3208687562 modified "2023-09-26" @default.
- W3208687562 title "Long non-coding RNA HEIH: a novel tumor activator in multiple cancers" @default.
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- W3208687562 doi "https://doi.org/10.1186/s12935-021-02272-5" @default.
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