Matches in SemOpenAlex for { <https://semopenalex.org/work/W3208693887> ?p ?o ?g. }
- W3208693887 endingPage "7950" @default.
- W3208693887 startingPage "7942" @default.
- W3208693887 abstract "Gangliosides, glycolipids that are abundant in the plasma membrane outer leaflet, play an integral role in cellular recognition, adhesion, and infection by interacting with different endogenous molecules, viruses, and toxins. Model membrane systems, such as ganglioside-enriched supported lipid bilayers (SLBs), present a useful tool for sensing, characterizing, and quantifying such interactions. In this work, we report the formation of ganglioside GM1-rich SLBs on conducting polymer electrodes using a solvent-assisted lipid bilayer assembly method to investigate changes in membrane electrical properties upon binding of the B subunit of cholera toxin. The sensing capabilities of our platform were investigated by varying both the receptor and the toxin concentrations in the system as well as using a complex sample (milk contaminated with the toxin) and monitoring the changes in the electrical properties of the membrane. Our work highlights the potential of such conducting polymer-supported biomembrane-based platforms for detecting the toxins within a complex environment, studying ganglioside-specific biomolecular interactions with toxins and screening inhibitory molecules to prevent these interactions." @default.
- W3208693887 created "2021-11-08" @default.
- W3208693887 creator A5018353256 @default.
- W3208693887 creator A5036896030 @default.
- W3208693887 creator A5046751786 @default.
- W3208693887 creator A5047815097 @default.
- W3208693887 creator A5050064702 @default.
- W3208693887 creator A5060266274 @default.
- W3208693887 creator A5075568011 @default.
- W3208693887 creator A5076048603 @default.
- W3208693887 creator A5078963346 @default.
- W3208693887 creator A5082493485 @default.
- W3208693887 date "2021-10-22" @default.
- W3208693887 modified "2023-09-25" @default.
- W3208693887 title "Detection of Ganglioside-Specific Toxin Binding with Biomembrane-Based Bioelectronic Sensors" @default.
- W3208693887 cites W1968526964 @default.
- W3208693887 cites W1973514792 @default.
- W3208693887 cites W1981154770 @default.
- W3208693887 cites W1996378090 @default.
- W3208693887 cites W2010117119 @default.
- W3208693887 cites W2010675225 @default.
- W3208693887 cites W2012212281 @default.
- W3208693887 cites W2014145796 @default.
- W3208693887 cites W2017645455 @default.
- W3208693887 cites W2018028416 @default.
- W3208693887 cites W2018354242 @default.
- W3208693887 cites W2029015814 @default.
- W3208693887 cites W2029100073 @default.
- W3208693887 cites W2048959224 @default.
- W3208693887 cites W2058720673 @default.
- W3208693887 cites W2063124395 @default.
- W3208693887 cites W2063976599 @default.
- W3208693887 cites W2065790254 @default.
- W3208693887 cites W2070908410 @default.
- W3208693887 cites W2089316692 @default.
- W3208693887 cites W2093227545 @default.
- W3208693887 cites W2094013663 @default.
- W3208693887 cites W2116889455 @default.
- W3208693887 cites W2124864045 @default.
- W3208693887 cites W2137827816 @default.
- W3208693887 cites W2150651714 @default.
- W3208693887 cites W2161779912 @default.
- W3208693887 cites W2169244589 @default.
- W3208693887 cites W2209232949 @default.
- W3208693887 cites W2211987955 @default.
- W3208693887 cites W2277311694 @default.
- W3208693887 cites W2312611373 @default.
- W3208693887 cites W2313690064 @default.
- W3208693887 cites W2333894357 @default.
- W3208693887 cites W2336569366 @default.
- W3208693887 cites W2460932277 @default.
- W3208693887 cites W2587838889 @default.
- W3208693887 cites W2763368374 @default.
- W3208693887 cites W2780621565 @default.
- W3208693887 cites W2792464789 @default.
- W3208693887 cites W2799900538 @default.
- W3208693887 cites W2840067365 @default.
- W3208693887 cites W2934237295 @default.
- W3208693887 cites W2937698100 @default.
- W3208693887 cites W2967773561 @default.
- W3208693887 cites W2982622063 @default.
- W3208693887 cites W3004522878 @default.
- W3208693887 cites W3023563932 @default.
- W3208693887 cites W3032834306 @default.
- W3208693887 cites W3035080970 @default.
- W3208693887 cites W3110675433 @default.
- W3208693887 cites W4211040736 @default.
- W3208693887 cites W4243919487 @default.
- W3208693887 cites W578603601 @default.
- W3208693887 doi "https://doi.org/10.1021/acsabm.1c00878" @default.
- W3208693887 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/35006775" @default.
- W3208693887 hasPublicationYear "2021" @default.
- W3208693887 type Work @default.
- W3208693887 sameAs 3208693887 @default.
- W3208693887 citedByCount "6" @default.
- W3208693887 countsByYear W32086938872021 @default.
- W3208693887 countsByYear W32086938872023 @default.
- W3208693887 crossrefType "journal-article" @default.
- W3208693887 hasAuthorship W3208693887A5018353256 @default.
- W3208693887 hasAuthorship W3208693887A5036896030 @default.
- W3208693887 hasAuthorship W3208693887A5046751786 @default.
- W3208693887 hasAuthorship W3208693887A5047815097 @default.
- W3208693887 hasAuthorship W3208693887A5050064702 @default.
- W3208693887 hasAuthorship W3208693887A5060266274 @default.
- W3208693887 hasAuthorship W3208693887A5075568011 @default.
- W3208693887 hasAuthorship W3208693887A5076048603 @default.
- W3208693887 hasAuthorship W3208693887A5078963346 @default.
- W3208693887 hasAuthorship W3208693887A5082493485 @default.
- W3208693887 hasConcept C125501631 @default.
- W3208693887 hasConcept C12554922 @default.
- W3208693887 hasConcept C185592680 @default.
- W3208693887 hasConcept C22222904 @default.
- W3208693887 hasConcept C2777006276 @default.
- W3208693887 hasConcept C2777331542 @default.
- W3208693887 hasConcept C2777367657 @default.
- W3208693887 hasConcept C39944091 @default.
- W3208693887 hasConcept C41625074 @default.
- W3208693887 hasConcept C55493867 @default.