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• W3208711377 abstract "Ozaki et al. first performed aortic valve replacement using autologous pericardium in 2007. Compared to mechanical and bioprosthetic valves which have apparent disadvantages, this technique has been an alternative with a promising safety and efficacy result. A comprehensive search was carried out in 4 databases (Pubmed, Cochrane Library, Proquest, Scopus) from February to March 2021 using search terms “autologous pericardium”, “aortic valve replacement”, and “aortic valve reconstruction”. Outcomes measured in this study were mortality, freedom of operation, thromboembolic and endocarditis event, and echocardiography finding. Risk bias of all studies was measured using MINORS criteria. A total of 12 studies involving 1427 subjects were included. The mean age was 64.95 years and 52.1% subjects were male. Mortality due to cardiac and noncardiac cause was 1.75%. Reoperation was needed in 1.12% subjects. Thromboembolic and endocarditis events occurred in 0.21% and 0.91% respectively. All studies reported lower average peak pressure gradient after surgery. Aortic valve replacement using autologous pericardium has a tolerable safety and efficacy. Ozaki et al. realizaron por primera vez el reemplazo de la válvula aórtica utilizando pericardio autólogo en 2007. En comparación con las válvulas mecánicas y bioprotésicas, que tienen aparentes desventajas, esta técnica ha sido una alternativa con un resultado prometedor de seguridad y eficacia. Se realizó una búsqueda exhaustiva en 4 bases de datos (Pubmed, Cochrane Library, Proquest y Scopus) de febrero a marzo de 2021 utilizando los términos de búsqueda pericardio autólogo, reemplazo valvular aórtico y reconstrucción valvular aórtica. Los resultados medidos en este estudio fueron mortalidad, libertad de operación, evento tromboembólico y hallazgo ecocardiográfico. El sesgo de riesgo de todos los estudios se midió mediante los criterios MINORS. Se incluyeron un total de 12 estudios con 1.427 sujetos. La edad media fue de 64,95 años y el 52,1% de los sujetos eran varones. La mortalidad por causa cardíaca y no cardíaca fue del 1,75%. Se produjeron episodios tromboembólicos y endocarditis en un 0,21% y un 0,91%, respectivamente. Todos los estudios informaron de un gradiente de presión máxima promedio más bajo después de la cirugía. La sustitución valvular aórtica mediante pericardio autólogo tiene una seguridad y eficacia tolerables." @default.
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• W3208711377 date "2021-10-01" @default.
• W3208711377 modified "2023-09-27" @default.
• W3208711377 title "Autologous pericardium for adult and elderly patients undergoing aortic valve replacement: A systematic review" @default.
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• W3208711377 doi "https://doi.org/10.1016/j.circv.2021.07.002" @default.
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