FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W3208802961> ?p ?o ?g. }

• W3208802961 endingPage "674" @default.
• W3208802961 startingPage "650" @default.
• W3208802961 abstract "Reaction-diffusion models have been proposed for decades to capture the growth of gliomas. Nevertheless, these models require an initial condition: the tumor cell density distribution over the whole brain at diagnosis time. Several works have proposed to relate this distribution to abnormalities visible on magnetic resonance imaging (MRI). In this work, we verify these hypotheses by stereotactic histological analysis of a non-operated brain with glioblastoma using a 3D-printed slicer. Cell density maps are computed from histological slides using a deep learning approach. The density maps are then registered to a postmortem MR image and related to an MR-derived geodesic distance map to the tumor core. The relation between the edema outlines visible on T2-FLAIR MRI and the distance to the core is also investigated. Our results suggest that (i) the previously proposed exponential decrease of the tumor cell density with the distance to the core is reasonable but (ii) the edema outlines would not correspond to a cell density iso-contour and (iii) the suggested tumor cell density at these outlines is likely overestimated. These findings highlight the limitations of conventional MRI to derive glioma cell density maps and the need for other initialization methods for reaction-diffusion models to be used in clinical practice." @default.
• W3208802961 created "2021-11-08" @default.
• W3208802961 creator A5021112552 @default.
• W3208802961 creator A5021794500 @default.
• W3208802961 creator A5046265328 @default.
• W3208802961 creator A5052532082 @default.
• W3208802961 creator A5059962541 @default.
• W3208802961 creator A5062356516 @default.
• W3208802961 creator A5063562292 @default.
• W3208802961 creator A5075817286 @default.
• W3208802961 creator A5081270901 @default.
• W3208802961 creator A5081897500 @default.
• W3208802961 creator A5086233511 @default.
• W3208802961 date "2021-10-29" @default.
• W3208802961 modified "2023-10-16" @default.
• W3208802961 title "Initial Condition Assessment for Reaction-Diffusion Glioma Growth Models: A Translational MRI-Histology (In)Validation Study" @default.
• W3208802961 cites W1492608162 @default.
• W3208802961 cites W1558633536 @default.
• W3208802961 cites W1967536168 @default.
• W3208802961 cites W1969035088 @default.
• W3208802961 cites W1986909146 @default.
• W3208802961 cites W1989532447 @default.
• W3208802961 cites W2021354031 @default.
• W3208802961 cites W2022101728 @default.
• W3208802961 cites W2030017300 @default.
• W3208802961 cites W2030959855 @default.
• W3208802961 cites W2042949685 @default.
• W3208802961 cites W2055272161 @default.
• W3208802961 cites W2064692536 @default.
• W3208802961 cites W2066276376 @default.
• W3208802961 cites W2071833700 @default.
• W3208802961 cites W2072057320 @default.
• W3208802961 cites W2078708982 @default.
• W3208802961 cites W2099742943 @default.
• W3208802961 cites W2112130807 @default.
• W3208802961 cites W2113147609 @default.
• W3208802961 cites W2130257210 @default.
• W3208802961 cites W2133059825 @default.
• W3208802961 cites W2133287637 @default.
• W3208802961 cites W2146933354 @default.
• W3208802961 cites W2148977460 @default.
• W3208802961 cites W2151538032 @default.
• W3208802961 cites W2170497549 @default.
• W3208802961 cites W2191292005 @default.
• W3208802961 cites W2281631628 @default.
• W3208802961 cites W2288156681 @default.
• W3208802961 cites W2331109341 @default.
• W3208802961 cites W2404695164 @default.
• W3208802961 cites W2804460770 @default.
• W3208802961 cites W2890990187 @default.
• W3208802961 cites W2918032088 @default.
• W3208802961 cites W2919520822 @default.
• W3208802961 cites W2947886832 @default.
• W3208802961 cites W2969948459 @default.
• W3208802961 cites W2977883299 @default.
• W3208802961 cites W3033449993 @default.
• W3208802961 cites W3044892863 @default.
• W3208802961 cites W3103145119 @default.
• W3208802961 cites W3104604121 @default.
• W3208802961 cites W3106919110 @default.
• W3208802961 cites W3110787789 @default.
• W3208802961 cites W3153595864 @default.
• W3208802961 cites W3154300213 @default.
• W3208802961 cites W4211132876 @default.
• W3208802961 cites W4254321319 @default.
• W3208802961 doi "https://doi.org/10.3390/tomography7040055" @default.
• W3208802961 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/8628987" @default.
• W3208802961 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/34842805" @default.
• W3208802961 hasPublicationYear "2021" @default.
• W3208802961 type Work @default.
• W3208802961 sameAs 3208802961 @default.
• W3208802961 citedByCount "3" @default.
• W3208802961 countsByYear W32088029612021 @default.
• W3208802961 countsByYear W32088029612022 @default.
• W3208802961 countsByYear W32088029612023 @default.
• W3208802961 crossrefType "journal-article" @default.
• W3208802961 hasAuthorship W3208802961A5021112552 @default.
• W3208802961 hasAuthorship W3208802961A5021794500 @default.
• W3208802961 hasAuthorship W3208802961A5046265328 @default.
• W3208802961 hasAuthorship W3208802961A5052532082 @default.
• W3208802961 hasAuthorship W3208802961A5059962541 @default.
• W3208802961 hasAuthorship W3208802961A5062356516 @default.
• W3208802961 hasAuthorship W3208802961A5063562292 @default.
• W3208802961 hasAuthorship W3208802961A5075817286 @default.
• W3208802961 hasAuthorship W3208802961A5081270901 @default.
• W3208802961 hasAuthorship W3208802961A5081897500 @default.
• W3208802961 hasAuthorship W3208802961A5086233511 @default.
• W3208802961 hasBestOaLocation W32088029611 @default.
• W3208802961 hasConcept C101070640 @default.
• W3208802961 hasConcept C114466953 @default.
• W3208802961 hasConcept C126838900 @default.
• W3208802961 hasConcept C142724271 @default.
• W3208802961 hasConcept C143409427 @default.
• W3208802961 hasConcept C199360897 @default.
• W3208802961 hasConcept C2776194525 @default.
• W3208802961 hasConcept C2778227246 @default.
• W3208802961 hasConcept C2989005 @default.
• W3208802961 hasConcept C41008148 @default.

• next