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- W320887466 abstract "To investigate the correlation between maternal leptin levels and 100 gram oral glucose test (OGTT) results as well as the correlation between leptin levels and the development of gestational diabetes mellitus (GDM) and glucose intolerance during pregnancy.104 subjects with gestational weeks ranging from 24 to 32 weeks who had increased 50 gr OGTT values (>140) were included in this study. After the screening test, 100 gr OGTT was administered to the subjects. Sixty cases were selected from these subjects; twenty patients with one abnormal test result were identified as glucose intolerant group (Group 1), 20 patients with two abnormal test values were diagnosed with GDM (Group 2) and 20 patients with normal test results constituted the control group. The serum leptin levels of the groups were measured with enzyme linked immunosorbent assay (ELISA).The serum leptin level was 8.4±5.1 ng/ml for group 1, 9.1±5.3 ng/ml for group 2 and 6.3±4.6 ng/ml for the control group. Although serum leptin levels for group 1 and 2 was observed to be higher than the control group, the result was not statistically significant (p>0.05). This result did not change after adjusting for body mass index (BMI).There is no statistically significant difference between leptin levels among three groups.Gebelikte maternal leptin seviyelerinin 100 gr oral glukoz tolerans testi sonuçları ve gestasyonel diyabet veya glukoz intoleransı gelişimi ile korelasyonunun araştırılması.Gebelik haftası 24–32 haftalar arasında olup 50 gr yükleme testi >140 mg/dl olan 104 vaka çalışmaya dahil edildi. tarama sonrası 100 gr testi uygulandı. Altmış vaka seçildi ve tek değeri bozuk olan 20 hasta “glukoz intolerans” grubu (Grup 1) olarak adlandırıldı. İki değeri yüksek olan hasta GDM tanısı aldı (Grup 2). Sonucu normal olan 20 hasta ise kontrol grubu olarak sınıflandırıldı. serum leptin düzeyleri ELISA ile ölçüldü.Serum leptin seviyeleri grup 1 için 8.4±5.1 ng/ml, grup 2 için 9.1±5.3 ng/m ve kontrol grubu için 6.3±4.6 ng/ml idi. Grup 1 ve 2 deki serum leptin düzeyleri kontrol grubuna göre yüksek olsa da bu istatistiksel olarak anlamlı değildi (p>0.05). Sonuçlar vücut kitle indeksi ayarlaması yapıldıktan sonra da değişmedi.Her üç grup arasında serum leptin seviyeleri açısından anlamlı fark saptanmadı." @default.
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- W320887466 date "2009-01-01" @default.
- W320887466 modified "2023-09-23" @default.
- W320887466 title "Investigation of the correlation between 100 gram oral glucose tolerance test results and maternal leptin levels during pregnancy." @default.
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