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• W3208904063 abstract "Introduction: Gastric cancer (GC) is the fifth most common cancer globally. While incidence of GC in the United States (US) is low, immigrants from high-incidence regions may have a comparable risk of GC as individuals in their home countries, though data demonstrating this risk are limited. We examined the association between census-tract level GC risk factors, including the proportion of foreign-born individuals, and GC incidence in New York State (NYS). Methods: Demographic data for census tracts in NYS, including percent foreign-born, percent high-risk country of origin (GC incidence at least twice that of the US), percent male, percent high-risk race/ethnicity (Black, Asian/Pacific Islander, American Indian/Alaskan Native, and Hispanic/Latino), percent with college degree or higher, median household income, and percent below the Federal Poverty Line (FPL), were obtained from the American Community Survey (ACS) from 2014 to 2018 and grouped into quintiles. Age-adjusted incidence rates for non-cardia (NCGC) and cardia gastric cancer (CGC) were calculated at the quintile level for census tracts between 2014 to 2018 using the NYS Cancer Registry Surveillance, Epidemiology, and End Results (SEER) Program Data Management System database. Linear regression was used to examine the relationship between quintile of demographic variables and age-adjusted incidence rates, and p-values for trend were calculated using the median of each quintile as a continuous variable. Results: A total of 3,917 NCGC and 2,269 CGC cases in NYS were identified. Quintile of the percent of individuals born in a high-risk country in each census tract was strongly associated with age-adjusted NCGC incidence (R2=0.99, p< 0.001). There were also strong positive associations for quintile of the percentage of the population that are foreign-born (R2=0.98, p=0.002), belong to a high-risk race (R2=0.95, p=0.005), identify as Hispanic/Latino (R2 = 0.93, p=0.008), and live below the FPL (R2 = 0.95, p=0.004) and NCGC incidence. We also saw strong negative associations for quintile of median household income (R2=0.93, p=0.009) and percent with a college degree or higher (R2=0.95, p=0.004) with NCGC incidence. Associations with CGC incidence were variable. Conclusion: Our results suggest an association between the proportion of individuals who immigrated from a high-risk country and NCGC incidence, reinforcing that immigrants from high-risk countries remain a vulnerable subgroup for NCGC in the US.Figure 1.: Panel a: Hospitalized COVID-19 patients with GI Symptoms on Admission demographic characteristics and ICU or non ICU admissions comparing with presence or no of respiratory symptoms. Panel b: Odds Ratio Estimates for ICU Admission in Patients with COVID-19 presenting with GI symptoms.Table 1.: Age-adjusted incidence rates and linear regression model R2 and p-trend values for quintile of census tract-level variables of interest and non-cardia and cardia gastric cancer cases diagnosed from 2014 to 2018 in New York State. 1: median value corresponds to the median percent (%) of individuals with the characteristic for each quintile 2: per 100,000 population 3: p-trend and R2 were calculated using the median value of each quintile as a continuous variable 4: medians are reported in USD ($)." @default.
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• W3208904063 date "2021-10-01" @default.
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• W3208904063 title "S1455 Heightened Risk for Gastric Cancer Among Immigrant Populations in New York State From High-Incidence Countries" @default.
• W3208904063 doi "https://doi.org/10.14309/01.ajg.0000779352.73351.99" @default.
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