Matches in SemOpenAlex for { <https://semopenalex.org/work/W3208946789> ?p ?o ?g. }
Showing items 1 to 98 of
98
with 100 items per page.
- W3208946789 endingPage "247" @default.
- W3208946789 startingPage "236" @default.
- W3208946789 abstract "In tree nut (TN) allergy, singleplex tests showed the diagnostic utility of rAna o 3, rCor a 14/nCor a 9, and nJug r 1/nJug r 4 for cashew/pistachio, hazelnut, and walnut allergies, respectively. However, disadvantages of the tests include high costs and excessive blood sampling in multi-sensitized patients, and a limited number of components. We investigated the utility of a multiplex macroarray (i.e., the ALEX2 test) in TN allergy.In 169 children, skin prick test, the component- and extract-specific IgEs of TNs were investigated for clinical reactivity and tolerance.The predictors (AUC = 0.962-0.749) of clinical reactivity to cashew, pistachio, hazelnut, and walnut were rPis v 1/rAna o 3, rPis v 1/rAna o 3/nPis v 2/nPis v 3, rCor a 14/nCor a 11/nCor a 9, and nJug r 1/nJug r 2/nJug r 6/nJug r 4, respectively. More than 93% of the patients with clinical reactivity to pistachio/cashew, hazelnut and walnut had positivity of (≥0.3 kUA/L) rPis v 1/rAna o 3, rCor a 14 and nJug r 1/nJug r 2, respectively. The highest accuracies of clinical reactivity to culprit nut were obtained with combination of rPis v 1, sIgE and SPT positivities for cashew/pistachio, rPis v 1 ≥ 1.0 kUA/L for pistachio, rCor a 14 ≥ 1.0 kUA/L for hazelnut and combination of nJug r 1 and nJug r 2 positivities for walnut, respectively. Also, higher concentrations of rPis v 1 (≥15.0 kUA/L), rCor a 14 (≥5.0 kUA/L) and nJug r 1/nJug r 2 (≥15.0 kUA/L) had %100 specificity and PPV in predicting clinical reactivity to cashew, hazelnut and walnut, respectively.Multiplex macroarray test is useful and reliable in the diagnosis of TN allergy in children, confirms and expands existing knowledge, and can be used as a stand-alone tool in the bottom-up diagnostic approach." @default.
- W3208946789 created "2021-11-08" @default.
- W3208946789 creator A5000599624 @default.
- W3208946789 creator A5007888623 @default.
- W3208946789 creator A5017608689 @default.
- W3208946789 creator A5019231824 @default.
- W3208946789 creator A5025291340 @default.
- W3208946789 date "2022-04-01" @default.
- W3208946789 modified "2023-10-14" @default.
- W3208946789 title "Multiplex component-based allergen macroarray test is useful to predict clinical reactivity to tree nuts in children" @default.
- W3208946789 cites W1964020267 @default.
- W3208946789 cites W2000831686 @default.
- W3208946789 cites W2013307032 @default.
- W3208946789 cites W2058044812 @default.
- W3208946789 cites W2107661462 @default.
- W3208946789 cites W2116502370 @default.
- W3208946789 cites W2120443449 @default.
- W3208946789 cites W2133233731 @default.
- W3208946789 cites W2133707124 @default.
- W3208946789 cites W2159446287 @default.
- W3208946789 cites W2256344073 @default.
- W3208946789 cites W2418916810 @default.
- W3208946789 cites W2511417182 @default.
- W3208946789 cites W2532179929 @default.
- W3208946789 cites W2601207416 @default.
- W3208946789 cites W2617484226 @default.
- W3208946789 cites W2620054251 @default.
- W3208946789 cites W2800921385 @default.
- W3208946789 cites W2802500726 @default.
- W3208946789 cites W2805091335 @default.
- W3208946789 cites W2883316674 @default.
- W3208946789 cites W2946421431 @default.
- W3208946789 cites W2972874439 @default.
- W3208946789 cites W2977593603 @default.
- W3208946789 cites W3032950830 @default.
- W3208946789 cites W3046665256 @default.
- W3208946789 cites W3085956564 @default.
- W3208946789 cites W3118337041 @default.
- W3208946789 cites W3119897390 @default.
- W3208946789 cites W3157858420 @default.
- W3208946789 cites W3171884389 @default.
- W3208946789 cites W3194110613 @default.
- W3208946789 cites W4210551439 @default.
- W3208946789 doi "https://doi.org/10.1016/j.alit.2021.10.001" @default.
- W3208946789 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/34755603" @default.
- W3208946789 hasPublicationYear "2022" @default.
- W3208946789 type Work @default.
- W3208946789 sameAs 3208946789 @default.
- W3208946789 citedByCount "8" @default.
- W3208946789 countsByYear W32089467892022 @default.
- W3208946789 countsByYear W32089467892023 @default.
- W3208946789 crossrefType "journal-article" @default.
- W3208946789 hasAuthorship W3208946789A5000599624 @default.
- W3208946789 hasAuthorship W3208946789A5007888623 @default.
- W3208946789 hasAuthorship W3208946789A5017608689 @default.
- W3208946789 hasAuthorship W3208946789A5019231824 @default.
- W3208946789 hasAuthorship W3208946789A5025291340 @default.
- W3208946789 hasBestOaLocation W32089467891 @default.
- W3208946789 hasConcept C144027150 @default.
- W3208946789 hasConcept C203014093 @default.
- W3208946789 hasConcept C207480886 @default.
- W3208946789 hasConcept C2780510475 @default.
- W3208946789 hasConcept C2781188995 @default.
- W3208946789 hasConcept C42972112 @default.
- W3208946789 hasConcept C60644358 @default.
- W3208946789 hasConcept C71924100 @default.
- W3208946789 hasConcept C86803240 @default.
- W3208946789 hasConceptScore W3208946789C144027150 @default.
- W3208946789 hasConceptScore W3208946789C203014093 @default.
- W3208946789 hasConceptScore W3208946789C207480886 @default.
- W3208946789 hasConceptScore W3208946789C2780510475 @default.
- W3208946789 hasConceptScore W3208946789C2781188995 @default.
- W3208946789 hasConceptScore W3208946789C42972112 @default.
- W3208946789 hasConceptScore W3208946789C60644358 @default.
- W3208946789 hasConceptScore W3208946789C71924100 @default.
- W3208946789 hasConceptScore W3208946789C86803240 @default.
- W3208946789 hasIssue "2" @default.
- W3208946789 hasLocation W32089467891 @default.
- W3208946789 hasLocation W32089467892 @default.
- W3208946789 hasOpenAccess W3208946789 @default.
- W3208946789 hasPrimaryLocation W32089467891 @default.
- W3208946789 hasRelatedWork W1982343230 @default.
- W3208946789 hasRelatedWork W2014471812 @default.
- W3208946789 hasRelatedWork W2037019085 @default.
- W3208946789 hasRelatedWork W2056313719 @default.
- W3208946789 hasRelatedWork W2145013427 @default.
- W3208946789 hasRelatedWork W2266295269 @default.
- W3208946789 hasRelatedWork W2611818413 @default.
- W3208946789 hasRelatedWork W2620054251 @default.
- W3208946789 hasRelatedWork W30803436 @default.
- W3208946789 hasRelatedWork W4283364380 @default.
- W3208946789 hasVolume "71" @default.
- W3208946789 isParatext "false" @default.
- W3208946789 isRetracted "false" @default.
- W3208946789 magId "3208946789" @default.
- W3208946789 workType "article" @default.