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- W3208952810 abstract "A series of activated vinyl azoles was hydrophosphinated in the presence of a chiral palladacycle catalyst under mild conditions to give enantioenriched phosphine azoles with moderate enantioselectivities and yields. The racemic phosphine azoles were transformed into eleven novel chelating phosphine-N-heterocyclic carbene (NHC) platinum complexes. The drug efficacies of nine selected phosphine-NHC platinum(II) chlorides in two cancer cell lines (MKN74 and MCF7) were evaluated, and two were found to exhibit activities comparable to that of cisplatin." @default.
- W3208952810 created "2021-11-08" @default.
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- W3208952810 date "2021-10-28" @default.
- W3208952810 modified "2023-10-12" @default.
- W3208952810 title "Chelating Phosphine–N-Heterocyclic Carbene Platinum Complexes via Catalytic Asymmetric Hydrophosphination and Their Cytotoxicity Toward MKN74 and MCF7 Cancer Cell Lines" @default.
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- W3208952810 doi "https://doi.org/10.1021/acs.inorgchem.1c02625" @default.
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