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- W3208970470 abstract "The testicular disorder of sex development (TDSD) is a rare condition characterized by a male appearance with a female karyotype. The most frequent cause of TDSD is misplacement of the sex determining region Y (SRY) gene on the X chromosome. Here, we report the generation of an induced pluripotent stem cell (iPSC) line from peripheral blood mononuclear cells of a patient with SRY-positive 46,XX TDSD. This cell line offers an unprecedented cellular model to investigate the profound manifestations like infertility of the male sex reversal patients, and serves as a useful tool to develop therapies for the disease." @default.
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- W3208970470 date "2021-12-01" @default.
- W3208970470 modified "2023-09-26" @default.
- W3208970470 title "Generation of an induced pluripotent stem cell line GZHMCi008-A derived from a patient with SRY-positive 46,XX testicular disorder of sex development" @default.
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- W3208970470 doi "https://doi.org/10.1016/j.scr.2021.102583" @default.
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