FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W3208989097> ?p ?o ?g. }

• W3208989097 endingPage "126889" @default.
• W3208989097 startingPage "126889" @default.
• W3208989097 abstract "Behavioral sensitization, thought to underlie some aspects of drug dependence, is typically measured as increased locomotion in response to repeated administration of a drug. The study aimed to investigate the (m-CF3-PhSe)2 effects on the acquisition, withdrawal, and re-exposure phases of morphine-induced behavioral locomotor sensitization.Swiss male mice were treated with saline or morphine at 10 mg/kg twice a day for 3 days; those of the morphine group were kept in the morphine withdrawal period (5 days). On day 9, mice were re-exposed to morphine. (m-CF3-PhSe)2 (10 mg/kg) or vehicle was administered at all phases of morphine protocol, and mice performed locomotor activity test. Oxidative stress markers and the levels of opioid, dopamine, and glutamate receptors were determined in samples of the cerebral cortex. (m-CF3-PhSe)2 administered at all phases of protocol attenuated morphine-induced locomotor sensitization.Mice exposed to morphine showed reduced weight gain and increased locomotor activity, but (m-CF3-PhSe)2 treatment attenuates the weight gain and behavioral hyperlocomotion effects. (m-CF3-PhSe)2, independent of the administration phase, modulated the increase of opioidergic (MOR, DOR, KOR) and glutamatergic (NMDA 2A and 2B) protein contents and attenuated redox imbalance in the cerebral cortex of mice exposed to morphine. However, (m-CF3-PhSe)2 did not modulate cortical protein levels of dopaminergic (D1 and D2) receptors in the acquisition phase of morphine-induced locomotor sensitization protocol.(m-CF3-PhSe)2 was effective against the behavioral and molecular alterations caused by morphine at all phases of locomotor sensitization." @default.
• W3208989097 created "2021-11-08" @default.
• W3208989097 creator A5021155903 @default.
• W3208989097 creator A5043926532 @default.
• W3208989097 creator A5067299062 @default.
• W3208989097 date "2022-01-01" @default.
• W3208989097 modified "2023-09-29" @default.
• W3208989097 title "m-CF3-substituted diphenyl diselenide attenuates all phases of morphine-induced behavioral locomotor sensitization in mice" @default.
• W3208989097 cites W1861269408 @default.
• W3208989097 cites W1967262742 @default.
• W3208989097 cites W1971711035 @default.
• W3208989097 cites W1983310681 @default.
• W3208989097 cites W1983314756 @default.
• W3208989097 cites W1983869923 @default.
• W3208989097 cites W1988279541 @default.
• W3208989097 cites W1988633467 @default.
• W3208989097 cites W2000853777 @default.
• W3208989097 cites W2004687905 @default.
• W3208989097 cites W2006368686 @default.
• W3208989097 cites W2021357478 @default.
• W3208989097 cites W2030959995 @default.
• W3208989097 cites W2033294541 @default.
• W3208989097 cites W2041748182 @default.
• W3208989097 cites W2043911241 @default.
• W3208989097 cites W2045218508 @default.
• W3208989097 cites W2058007986 @default.
• W3208989097 cites W2060069408 @default.
• W3208989097 cites W2064870599 @default.
• W3208989097 cites W2064981998 @default.
• W3208989097 cites W2066848874 @default.
• W3208989097 cites W2067114364 @default.
• W3208989097 cites W2068085565 @default.
• W3208989097 cites W2079086643 @default.
• W3208989097 cites W2084024177 @default.
• W3208989097 cites W2085665176 @default.
• W3208989097 cites W2088239718 @default.
• W3208989097 cites W2091541835 @default.
• W3208989097 cites W2092912202 @default.
• W3208989097 cites W2106719141 @default.
• W3208989097 cites W2108805116 @default.
• W3208989097 cites W2113070351 @default.
• W3208989097 cites W2122283279 @default.
• W3208989097 cites W2122916434 @default.
• W3208989097 cites W2143429166 @default.
• W3208989097 cites W2153998371 @default.
• W3208989097 cites W2155132056 @default.
• W3208989097 cites W2163951254 @default.
• W3208989097 cites W2165379966 @default.
• W3208989097 cites W2169863475 @default.
• W3208989097 cites W2174764226 @default.
• W3208989097 cites W2534035576 @default.
• W3208989097 cites W2620264939 @default.
• W3208989097 cites W2745847860 @default.
• W3208989097 cites W2750980950 @default.
• W3208989097 cites W2762545024 @default.
• W3208989097 cites W2795653696 @default.
• W3208989097 cites W2911136597 @default.
• W3208989097 cites W2917642469 @default.
• W3208989097 cites W2985632750 @default.
• W3208989097 cites W3007303177 @default.
• W3208989097 cites W4232534952 @default.
• W3208989097 cites W4240863575 @default.
• W3208989097 cites W4251698688 @default.
• W3208989097 cites W4293247451 @default.
• W3208989097 doi "https://doi.org/10.1016/j.jtemb.2021.126889" @default.
• W3208989097 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/34798514" @default.
• W3208989097 hasPublicationYear "2022" @default.
• W3208989097 type Work @default.
• W3208989097 sameAs 3208989097 @default.
• W3208989097 citedByCount "2" @default.
• W3208989097 countsByYear W32089890972023 @default.
• W3208989097 crossrefType "journal-article" @default.
• W3208989097 hasAuthorship W3208989097A5021155903 @default.
• W3208989097 hasAuthorship W3208989097A5043926532 @default.
• W3208989097 hasAuthorship W3208989097A5067299062 @default.
• W3208989097 hasConcept C126322002 @default.
• W3208989097 hasConcept C137183658 @default.
• W3208989097 hasConcept C15744967 @default.
• W3208989097 hasConcept C16568411 @default.
• W3208989097 hasConcept C169760540 @default.
• W3208989097 hasConcept C170493617 @default.
• W3208989097 hasConcept C178790620 @default.
• W3208989097 hasConcept C185592680 @default.
• W3208989097 hasConcept C2081992 @default.
• W3208989097 hasConcept C2776217527 @default.
• W3208989097 hasConcept C2777389121 @default.
• W3208989097 hasConcept C2777981454 @default.
• W3208989097 hasConcept C2779754636 @default.
• W3208989097 hasConcept C2781063702 @default.
• W3208989097 hasConcept C2985495968 @default.
• W3208989097 hasConcept C513476851 @default.
• W3208989097 hasConcept C553756173 @default.
• W3208989097 hasConcept C55493867 @default.
• W3208989097 hasConcept C67018056 @default.
• W3208989097 hasConcept C71924100 @default.
• W3208989097 hasConcept C98274493 @default.
• W3208989097 hasConceptScore W3208989097C126322002 @default.
• W3208989097 hasConceptScore W3208989097C137183658 @default.

• next