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- W3209054927 abstract "The centromere is the constricted chromosomal region required for the correct separation of the genetic material at cell division. The kinetochore protein complex assembles at the centromere and captures microtubules emanating from the centrosome to orchestrate chromosome segregation in mitosis and meiosis. Asymmetric cell division (ACD) is a special type of mitosis that generates two daughter cells with different fates. Epigenetic mechanisms operating at the centromere have been proposed to contribute to ACD. Recent studies have shown that an asymmetric distribution of CENP-A—the centromere-specific histone H3 variant—between sister chromatids can bias chromosome segregation in ACD. In stem cells, this leads to non-random sister chromatid segregation, which can affect cell fate. These findings support the ‘silent sister' hypothesis, according to which the mechanisms of ACD are epigenetically regulated through centromeres. Here, we review the recent data implicating centromeres in ACDs and cell fate in Drosophila melanogaster female and male germline stem cells." @default.
- W3209054927 created "2021-11-08" @default.
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- W3209054927 date "2021-11-01" @default.
- W3209054927 modified "2023-10-17" @default.
- W3209054927 title "Centromere function in asymmetric cell division in <i>Drosophila</i> female and male germline stem cells" @default.
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- W3209054927 cites W1965281877 @default.
- W3209054927 cites W1969476674 @default.
- W3209054927 cites W1970549330 @default.
- W3209054927 cites W1981049421 @default.
- W3209054927 cites W1982337820 @default.
- W3209054927 cites W1982765286 @default.
- W3209054927 cites W1983356538 @default.
- W3209054927 cites W1983952522 @default.
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- W3209054927 cites W1993076246 @default.
- W3209054927 cites W2004910827 @default.
- W3209054927 cites W20126109 @default.
- W3209054927 cites W2015495840 @default.
- W3209054927 cites W2015796780 @default.
- W3209054927 cites W2023980699 @default.
- W3209054927 cites W2028945975 @default.
- W3209054927 cites W2037048003 @default.
- W3209054927 cites W2037405848 @default.
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- W3209054927 cites W2046058115 @default.
- W3209054927 cites W2048039677 @default.
- W3209054927 cites W2056604483 @default.
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- W3209054927 doi "https://doi.org/10.1098/rsob.210107" @default.
- W3209054927 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/8564616" @default.
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