FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W3209069186> ?p ?o ?g. }

• W3209069186 endingPage "e68" @default.
• W3209069186 startingPage "e67" @default.
• W3209069186 abstract "Abstract Primary Subject area Neonatal-Perinatal Medicine Background Universal head ultrasound (HUS) screening for severe neurological injury (SNI) injury is recommended for infants born &lt; 32 weeks’ gestational age (GA). However, the risk of SNI varies inversely with GA at birth and other known risk factors; therefore targeted screening may be more appropriate. Objectives The objective of the study is to develop a risk-stratified HUS screening protocol for infants born &lt; 32 weeks’ to identify SNI accurately while minimizing resource use. Design/Methods Retrospective cohort study of infants born 23-31 weeks’ admitted to a tertiary NICU between 2011-2017. Patient characteristics were extracted from the Canadian Neonatal Network database. All HUS were individually reviewed by a trained abstractor and grouped based on date of exam relative to birth: ≤ 3 days, 4-7 days, 8-14 days, 28-42 days and 35-42 weeks’ corrected GA. Severe neurological injury was defined as intraventricular hemorrhage grade ≥ 3 and/or periventricular leukomalacia on HUS. Logistic regression models were used to identify perinatal risk factors for SNI and determine the number and timing of HUS with highest diagnostic accuracy. Results Of 651 infants included, 72 (11%) developed SNI. Independent risk factors for SNI were GA &lt;29 weeks (AOR 3.09, 95% CI 1.65-6.08), vasopressors (AOR 2.95, 95% CI 1.24-6.80) and mechanical ventilation on day of admission (AOR 2.22, 95% CI 1.23-4.11). Infants were grouped into three screening groups based on their exposure to these risk factors (Table 1). Diagnostic accuracy of 63 models of combinations of HUS time points were assessed, and a screening protocol was developed based on the specific time points of HUS that maximized diagnostic accuracy (area under the ROC curve &gt;0.9) while minimizing number of HUS for each screening group (Table 2). Using this protocol could reduce the total number of HUS performed by 920 (40%) and median number of HUS per infant from three (IQR 2-4) to 2 (IQR 1-2; p &lt; 0 .001). Conclusion Implementation of a risk factor-based HUS screening protocol may reduce resource use while maintaining high diagnostic accuracy for SNI, and reflects choosing wisely in the NICU." @default.
• W3209069186 created "2021-11-08" @default.
• W3209069186 creator A5002610885 @default.
• W3209069186 creator A5017546940 @default.
• W3209069186 creator A5045618911 @default.
• W3209069186 creator A5067935598 @default.
• W3209069186 creator A5078854927 @default.
• W3209069186 creator A5035271071 @default.
• W3209069186 date "2021-10-01" @default.
• W3209069186 modified "2023-09-23" @default.
• W3209069186 title "93 Timing and frequency of head ultrasound screening to identify severe neurological injury among very preterm infants" @default.
• W3209069186 doi "https://doi.org/10.1093/pch/pxab061.075" @default.
• W3209069186 hasPublicationYear "2021" @default.
• W3209069186 type Work @default.
• W3209069186 sameAs 3209069186 @default.
• W3209069186 citedByCount "0" @default.
• W3209069186 crossrefType "journal-article" @default.
• W3209069186 hasAuthorship W3209069186A5002610885 @default.
• W3209069186 hasAuthorship W3209069186A5017546940 @default.
• W3209069186 hasAuthorship W3209069186A5035271071 @default.
• W3209069186 hasAuthorship W3209069186A5045618911 @default.
• W3209069186 hasAuthorship W3209069186A5067935598 @default.
• W3209069186 hasAuthorship W3209069186A5078854927 @default.
• W3209069186 hasBestOaLocation W32090691862 @default.
• W3209069186 hasConcept C126322002 @default.
• W3209069186 hasConcept C141071460 @default.
• W3209069186 hasConcept C151956035 @default.
• W3209069186 hasConcept C167135981 @default.
• W3209069186 hasConcept C187212893 @default.
• W3209069186 hasConcept C2777080012 @default.
• W3209069186 hasConcept C2778376644 @default.
• W3209069186 hasConcept C2779234561 @default.
• W3209069186 hasConcept C2779252433 @default.
• W3209069186 hasConcept C2780123866 @default.
• W3209069186 hasConcept C42219234 @default.
• W3209069186 hasConcept C54355233 @default.
• W3209069186 hasConcept C71924100 @default.
• W3209069186 hasConcept C72563966 @default.
• W3209069186 hasConcept C86803240 @default.
• W3209069186 hasConceptScore W3209069186C126322002 @default.
• W3209069186 hasConceptScore W3209069186C141071460 @default.
• W3209069186 hasConceptScore W3209069186C151956035 @default.
• W3209069186 hasConceptScore W3209069186C167135981 @default.
• W3209069186 hasConceptScore W3209069186C187212893 @default.
• W3209069186 hasConceptScore W3209069186C2777080012 @default.
• W3209069186 hasConceptScore W3209069186C2778376644 @default.
• W3209069186 hasConceptScore W3209069186C2779234561 @default.
• W3209069186 hasConceptScore W3209069186C2779252433 @default.
• W3209069186 hasConceptScore W3209069186C2780123866 @default.
• W3209069186 hasConceptScore W3209069186C42219234 @default.
• W3209069186 hasConceptScore W3209069186C54355233 @default.
• W3209069186 hasConceptScore W3209069186C71924100 @default.
• W3209069186 hasConceptScore W3209069186C72563966 @default.
• W3209069186 hasConceptScore W3209069186C86803240 @default.
• W3209069186 hasIssue "Supplement_1" @default.
• W3209069186 hasLocation W32090691861 @default.
• W3209069186 hasLocation W32090691862 @default.
• W3209069186 hasOpenAccess W3209069186 @default.
• W3209069186 hasPrimaryLocation W32090691861 @default.
• W3209069186 hasRelatedWork W1639193670 @default.
• W3209069186 hasRelatedWork W2007644749 @default.
• W3209069186 hasRelatedWork W2033607346 @default.
• W3209069186 hasRelatedWork W2427130313 @default.
• W3209069186 hasRelatedWork W2505524256 @default.
• W3209069186 hasRelatedWork W3111843774 @default.
• W3209069186 hasRelatedWork W3165043782 @default.
• W3209069186 hasRelatedWork W4220664808 @default.
• W3209069186 hasRelatedWork W4225108138 @default.
• W3209069186 hasRelatedWork W4292615648 @default.
• W3209069186 hasVolume "26" @default.
• W3209069186 isParatext "false" @default.
• W3209069186 isRetracted "false" @default.
• W3209069186 magId "3209069186" @default.
• W3209069186 workType "article" @default.