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• W3209080981 startingPage "12206" @default.
• W3209080981 abstract "A mechanochromic polymer, polydiacetylene, changes color upon ligand binding, being a popular material in biosensing. However, whether it can also detect ligand functions in addition to binding is left understudied. In this work, we report that the polydiacetylene can be used to determine the net charges and the mode of actions (carpet model, toroidal pore model, etc.) of antimicrobial peptides and detergents via EC50 and Hill coefficients from the colorimetric response-dose curves. This opens a potential for high-throughput peptide screening by functions, which is difficult with the conventional methods." @default.
• W3209080981 created "2021-11-08" @default.
• W3209080981 creator A5029072308 @default.
• W3209080981 creator A5084514176 @default.
• W3209080981 date "2021-10-27" @default.
• W3209080981 modified "2023-10-02" @default.
• W3209080981 title "Analysis of PDA Dose Curves for the Extraction of Antimicrobial Peptide Properties" @default.
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• W3209080981 doi "https://doi.org/10.1021/acs.jpcb.1c07533" @default.
• W3209080981 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/34706534" @default.
• W3209080981 hasPublicationYear "2021" @default.
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