Matches in SemOpenAlex for { <https://semopenalex.org/work/W3209117652> ?p ?o ?g. }
Showing items 1 to 76 of
76
with 100 items per page.
- W3209117652 endingPage "S1243" @default.
- W3209117652 startingPage "S1243" @default.
- W3209117652 abstract "Introduction: Intra-abdominal mass is a finding often encountered in clinical practice. The differential diagnosis of an intra-abdominal mass is very broad including traumatic lesions, vessel abnormalities, renal pathology, benign tumors, invasive malignancy, and other entities. Even though many patients are diagnosed incidentally, some will have progressed disease, leading to signs/symptoms secondary to mass burden and compression effects. Here we will present a neglected rare mesenchymal neoplasm case. Case Description/Methods: FM, a 58-year-old man without significant medical history other than heavy smoking presented with abdominal distention, constipation, incontinence, hematochezia, rectal prolapse and progressive severe LE edema. Interestingly, 10 years ago an “abdominal mass” was detected incidentally but the patient never sought medical attention for appropriate work-up. A CT of the abdomen and pelvis revealed a large intra-abdominal mesenteric mass, 30x25x20 cm, without evidence of bowel obstruction or hydronephrosis. Biopsy of the lesion showed high grade spindle cell gastrointestinal stromal tumor (GIST), likely arising from omentum or terminal ileum. Further work-up revealed no metastatic disease and patient underwent surgical excision of the 24-pounds mass along with en-bloc mid ileum resection and left hemicolectomy. Biopsy further characterized the surgically excised mass as liposarcoma arising from colon. Post-operatively patient developed ileus, resolved with conservative management but otherwise his course was uneventful, and patient scheduled to follow up with oncology services for Imatinib therapy. Discussion: GIST are relatively rare mesenchymal tumors. Usually, they are detected incidentally but, in some cases, they may grow causing non-specific symptoms such as early satiety and bloating, while in rare cases, tumors may grow large enough to cause severe symptoms (compression effects, pain, bowel obstruction, GI bleeding). Initial evaluation includes screening for metastatic disease with CTAP or PET, while for large tumors ( ≥2cm) chest imaging is also indicated. Assessment of mutations is also suggested by literature. Response to systemic therapy, like Imatinib, correlates with better outcomes in GIST with specific gene mutations such as KIT. Prognosis is variable depending on tumor characteristics like tumor size and mitotic index while the primary tumor location is also important to predict disease outcome.Figure 1.: CT scan abdomen & pelvis." @default.
- W3209117652 created "2021-11-08" @default.
- W3209117652 creator A5009708750 @default.
- W3209117652 creator A5064501162 @default.
- W3209117652 creator A5067059663 @default.
- W3209117652 creator A5078326534 @default.
- W3209117652 date "2021-10-01" @default.
- W3209117652 modified "2023-10-14" @default.
- W3209117652 title "S3004 Massive Intra-Abdominal Mass in a 58-Year-Old Patient" @default.
- W3209117652 doi "https://doi.org/10.14309/01.ajg.0000785548.14857.58" @default.
- W3209117652 hasPublicationYear "2021" @default.
- W3209117652 type Work @default.
- W3209117652 sameAs 3209117652 @default.
- W3209117652 citedByCount "0" @default.
- W3209117652 crossrefType "journal-article" @default.
- W3209117652 hasAuthorship W3209117652A5009708750 @default.
- W3209117652 hasAuthorship W3209117652A5064501162 @default.
- W3209117652 hasAuthorship W3209117652A5067059663 @default.
- W3209117652 hasAuthorship W3209117652A5078326534 @default.
- W3209117652 hasBestOaLocation W32091176521 @default.
- W3209117652 hasConcept C121608353 @default.
- W3209117652 hasConcept C126322002 @default.
- W3209117652 hasConcept C126838900 @default.
- W3209117652 hasConcept C141071460 @default.
- W3209117652 hasConcept C142724271 @default.
- W3209117652 hasConcept C16930146 @default.
- W3209117652 hasConcept C2775922572 @default.
- W3209117652 hasConcept C2777007597 @default.
- W3209117652 hasConcept C2777643690 @default.
- W3209117652 hasConcept C2778435480 @default.
- W3209117652 hasConcept C2779399171 @default.
- W3209117652 hasConcept C2779983558 @default.
- W3209117652 hasConcept C2780505380 @default.
- W3209117652 hasConcept C2780801072 @default.
- W3209117652 hasConcept C2781054515 @default.
- W3209117652 hasConcept C526805850 @default.
- W3209117652 hasConcept C71924100 @default.
- W3209117652 hasConceptScore W3209117652C121608353 @default.
- W3209117652 hasConceptScore W3209117652C126322002 @default.
- W3209117652 hasConceptScore W3209117652C126838900 @default.
- W3209117652 hasConceptScore W3209117652C141071460 @default.
- W3209117652 hasConceptScore W3209117652C142724271 @default.
- W3209117652 hasConceptScore W3209117652C16930146 @default.
- W3209117652 hasConceptScore W3209117652C2775922572 @default.
- W3209117652 hasConceptScore W3209117652C2777007597 @default.
- W3209117652 hasConceptScore W3209117652C2777643690 @default.
- W3209117652 hasConceptScore W3209117652C2778435480 @default.
- W3209117652 hasConceptScore W3209117652C2779399171 @default.
- W3209117652 hasConceptScore W3209117652C2779983558 @default.
- W3209117652 hasConceptScore W3209117652C2780505380 @default.
- W3209117652 hasConceptScore W3209117652C2780801072 @default.
- W3209117652 hasConceptScore W3209117652C2781054515 @default.
- W3209117652 hasConceptScore W3209117652C526805850 @default.
- W3209117652 hasConceptScore W3209117652C71924100 @default.
- W3209117652 hasIssue "1" @default.
- W3209117652 hasLocation W32091176521 @default.
- W3209117652 hasLocation W32091176522 @default.
- W3209117652 hasOpenAccess W3209117652 @default.
- W3209117652 hasPrimaryLocation W32091176521 @default.
- W3209117652 hasRelatedWork W2359347383 @default.
- W3209117652 hasRelatedWork W2385050303 @default.
- W3209117652 hasRelatedWork W2410273514 @default.
- W3209117652 hasRelatedWork W2599275129 @default.
- W3209117652 hasRelatedWork W2970542908 @default.
- W3209117652 hasRelatedWork W2979099782 @default.
- W3209117652 hasRelatedWork W3136767724 @default.
- W3209117652 hasRelatedWork W3206892513 @default.
- W3209117652 hasRelatedWork W3216694441 @default.
- W3209117652 hasRelatedWork W4284885068 @default.
- W3209117652 hasVolume "116" @default.
- W3209117652 isParatext "false" @default.
- W3209117652 isRetracted "false" @default.
- W3209117652 magId "3209117652" @default.
- W3209117652 workType "article" @default.