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• W3209325974 abstract "The treatment of choice for Ménière disease (MD) aims at preventing severity and frequency of vertigo attacks. The purpose of this study was to evaluate the effectiveness of ventilation tube (VT) placement on vertigo control in patients affected by MD with no response to standard medical therapy.76 consecutive outpatients diagnosed with definite MD who failed medical therapy received VT insertion at the Department of Otolaryngology Head and Neck Surgery, Ospedale del Mare, Naples, Italy, with a 3-year follow up.Over the long term, VT placement was effective in controlling vertigo in 61.8% of patients. In the control group treated with standard preventive care (SPC) alone, all patients continued to experience recurrent vertigo during the entire study. Comparison of survival curves by using the log-rank test shows that significant differences in survival exist between subjects treated with VT placement and the control sample (p = 0.001).Our long-term follow-up confirms that VT placement is an effective and safe management option in intractable definite MD, especially in the elderly or in those refusing more invasive treatments.Miglioramento dei sintomi con tubicino trans-timpanico nella malattia di Ménière: osservazioni preliminari.Il trattamento della malattia di Ménière (MD) mira a prevenire gravità e frequenza delle crisi di vertigine. Lo studio ha valutato l’efficacia del posizionamento del tubicino di ventilazione (VT) trans-timpanico nel controllo delle vertigini nei pazienti affetti da MD non responsivi alla terapia medica standard.76 pazienti con diagnosi di MD definita non responsivi alla terapia medica sono stati trattati con posizionamento del VT presso l’UOC ORL dell’Ospedale del Mare, Napoli, Italia, con un follow-up di 3 anni.Il posizionamento del VT si è dimostrato efficace nel controllare le crisi di vertigine nel 61,8% dei pazienti. Nel gruppo controllo, sottoposto alla sola terapia preventiva standard (SPC), tutti i pazienti hanno riportato persistenza di crisi di vertigine ricorrente durante l’intero periodo di studio. Il confronto delle curve di sopravvivenza mediante log-rank test ha evidenziato differenze statisticamente significative nella sopravvivenza tra i soggetti trattati con VT e il campione di controllo (p = 0,001).I nostri risultati confermano che tale procedura può rappresentare il trattamento di scelta nella gestione efficace e sicura di tali soggetti, specialmente se anziani o che rifiutino trattamenti più invasivi." @default.
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• W3209325974 date "2021-10-01" @default.
• W3209325974 modified "2023-10-02" @default.
• W3209325974 title "Symptom improvement after transtympanic tube placement in Ménière’s disease: preliminary observations" @default.
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• W3209325974 doi "https://doi.org/10.14639/0392-100x-n1705" @default.
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