Matches in SemOpenAlex for { <https://semopenalex.org/work/W3209359780> ?p ?o ?g. }
Showing items 1 to 61 of
61
with 100 items per page.
- W3209359780 endingPage "150" @default.
- W3209359780 startingPage "141" @default.
- W3209359780 abstract "This short review on the chemistry, pharmacological properties and patents of obovatol and obovatal from Magnolia obovata is the first publication. Pharmacological properties are focused on anti-cancer, anti-inflammatory, anti-platelet and neuroprotective activities. Obovatol and obovatal were first isolated from the leaves of M. obovata. Also reported in the bark and fruits of M. obovata, obovatol and obovatal are neolignans i.e., biphenolic compounds bearing a C‒O coupling. Other classes of compounds isolated and identified from M. obovata include sesquiterpene-neolignans, dineolignans, trineolignan, lignans, dilignans, phenylpropanoids, phenylethanoid glycosides, flavonoids, phenolic acids, alkaloids, sesquiterpenes, ketone and sterols. The anticancer properties of obovatol and obovatal involve apoptosis, inhibition of the growth, migration and invasion of cancer cell lines. However, obovatol displays cytotoxicity against cancer cells but not obovatal. Similarly, anti-inflammatory, anti-platelet, neuroprotective, anxiolytic and other pharmacological activities were only observed in obovatol. The disparity in pharmacological properties of obovatol and obovatal may be attributed to the ‒CHO group present in obovatal but absent in obovatol. From 2007 to 2013, eight patents were published on obovatol with one mentioning obovatal. They were all published at the U.S. Patent and Trademark Office by scientists of the Korea Research Institute of Bioscience and Biotechnology (KRIBB) as inventors and assignee, respectively. Some future research and prospects are suggested." @default.
- W3209359780 created "2021-11-08" @default.
- W3209359780 creator A5024762157 @default.
- W3209359780 creator A5027591236 @default.
- W3209359780 creator A5066643907 @default.
- W3209359780 date "2021-09-30" @default.
- W3209359780 modified "2023-09-23" @default.
- W3209359780 title "A Short Review on the Chemistry, Pharmacological Properties and Patents of Obovatol and Obovatal (Neolignans) from Magnolia obovata" @default.
- W3209359780 doi "https://doi.org/10.20307/nps.2021.27.3.141" @default.
- W3209359780 hasPublicationYear "2021" @default.
- W3209359780 type Work @default.
- W3209359780 sameAs 3209359780 @default.
- W3209359780 citedByCount "0" @default.
- W3209359780 crossrefType "journal-article" @default.
- W3209359780 hasAuthorship W3209359780A5024762157 @default.
- W3209359780 hasAuthorship W3209359780A5027591236 @default.
- W3209359780 hasAuthorship W3209359780A5066643907 @default.
- W3209359780 hasBestOaLocation W32093597801 @default.
- W3209359780 hasConcept C185592680 @default.
- W3209359780 hasConcept C194671627 @default.
- W3209359780 hasConcept C25498285 @default.
- W3209359780 hasConcept C2779326954 @default.
- W3209359780 hasConcept C2780978374 @default.
- W3209359780 hasConcept C2781264555 @default.
- W3209359780 hasConcept C556039675 @default.
- W3209359780 hasConcept C71240020 @default.
- W3209359780 hasConcept C71924100 @default.
- W3209359780 hasConcept C86803240 @default.
- W3209359780 hasConcept C98274493 @default.
- W3209359780 hasConceptScore W3209359780C185592680 @default.
- W3209359780 hasConceptScore W3209359780C194671627 @default.
- W3209359780 hasConceptScore W3209359780C25498285 @default.
- W3209359780 hasConceptScore W3209359780C2779326954 @default.
- W3209359780 hasConceptScore W3209359780C2780978374 @default.
- W3209359780 hasConceptScore W3209359780C2781264555 @default.
- W3209359780 hasConceptScore W3209359780C556039675 @default.
- W3209359780 hasConceptScore W3209359780C71240020 @default.
- W3209359780 hasConceptScore W3209359780C71924100 @default.
- W3209359780 hasConceptScore W3209359780C86803240 @default.
- W3209359780 hasConceptScore W3209359780C98274493 @default.
- W3209359780 hasIssue "3" @default.
- W3209359780 hasLocation W32093597801 @default.
- W3209359780 hasOpenAccess W3209359780 @default.
- W3209359780 hasPrimaryLocation W32093597801 @default.
- W3209359780 hasRelatedWork W1980673861 @default.
- W3209359780 hasRelatedWork W1987987784 @default.
- W3209359780 hasRelatedWork W2003802136 @default.
- W3209359780 hasRelatedWork W2051664517 @default.
- W3209359780 hasRelatedWork W2062170069 @default.
- W3209359780 hasRelatedWork W2078650224 @default.
- W3209359780 hasRelatedWork W2091710849 @default.
- W3209359780 hasRelatedWork W2155738692 @default.
- W3209359780 hasRelatedWork W2834046156 @default.
- W3209359780 hasRelatedWork W3033818832 @default.
- W3209359780 hasVolume "27" @default.
- W3209359780 isParatext "false" @default.
- W3209359780 isRetracted "false" @default.
- W3209359780 magId "3209359780" @default.
- W3209359780 workType "article" @default.