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• W3209398969 abstract "Background Although minimally invasive technology has been widely used in hepatectomy, it remains controversial with regards to liver transplantation, especially in donors right hepatectomy. Herein, we compared the short-term safety and efficacy of minimally invasive donors right hepatectomy (MIDRH) with open donors right hepatectomy (ODRH). Methods A systematic literature search was carried out using PubMed, Embase, Web of Science and the Cochrane Library database in order to identify comparison studies of MIDRH and ODRH. Next, we obtained the relevant data, and carried out the meta-analysis. Results This meta-analysis included 12 studies, which included 1755 cases that underwent donors right hepatectomy. Compared to ODRH, patients that underwent MIDRH had less bleeding (SWD = −0.52, p<0.001), shorter hospital stays (SWD = −0.58, p < 0.001) and lower overall postoperative complications of donors (RR = 0.74, p = 0.008). However, MIDRH was found to be associated with prolonged operative times (SWD = 0.74, p < 0.001), as well as a higher rate of biliary complications in donors (RR = 2.26, p = 0.007) and recipients (RR = 1.69, p < 0.001). There were no statistically significant differences between MIDRH and ODRH in postoperative liver function, rate of major complications and vascular complications of both donors and recipients and overall postoperative complications. Discussion MIDRH is superior to ODRH with regards to intraoperative bleeding, postoperative hospital stay and overall donor complications. Although biliary-related complications are higher, it is feasible to develop MIDRH in experienced liver transplant centers. However, higher-quality research is still needed for corroboration. Highlights The first meta-analysis evaluated the clinical outcomes of MIDRH comparing with ODRH. MIDRH reduced intraoperative blood loss, postoperative hospital stay and overall complications. The biliary complications of donors and recipients were higher in MIDRH than ODRH." @default.
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• W3209398969 date "2021-11-01" @default.
• W3209398969 modified "2023-09-27" @default.
• W3209398969 title "Minimally invasive versus open living donors right hepatectomy: A systematic review and meta-analysis" @default.
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• W3209398969 doi "https://doi.org/10.1016/j.ijsu.2021.106152" @default.
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