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- W3209505993 abstract "Purpose: To identify risk factors for postoperative pancreatic fistula (POPF) after pancreaticoduodenectomy (PD) Methods: We conducted a retrospective analysis of prospectively collected data of 62 succesive cases of PD performed in our hospital from October 2018 until December 2020. The International Study Group of Pancreatic Fistula (ISGPF) definition was used for the detection of patients with pancreatic fistula (PF). Risk factors for PF were analyzed using Spss programm (version 26) Results: A total of 22 (35.5%) cases of PF occured after PD, including 17 (27.4%) cases of Grade B and 5 (8.1%) cases of Grade C. Pearson Bivariate Correlation showed no significant correlation between POPF and the following factors: Gender, age, BMI, disease, preoperative bilirubin, albumine, ferritine, Ca 19-9, CEA, HbA1c, presence of jaundice and cholecystectomy prior to operation. Intraoperative factors with no significant correlation were pancreas texture, pancreas cutting surface area, duration of surgery, transfusion, fluid administration, anastomotic technique used and preservation of the pylorus. Conversely, a significant correlation was observed between POPF and the following factors: presence of diabetes (p = 0.037), prior to operation, elevated levels of CRP on the 3rd (p = 0.043) and 5th (p = 0.037) postoperative day (POD) and smaller pancreatic duct diameter (p = 0.029). ROC Curve analysis showed that CRP levels greater than 124 mg/l on the 5th POD has 76.2% sensitivity and 55% specificity for POPF (AUC = 0.66) Conclusion: Those are preliminary results of a single center prospective study searching for risk factors for POPF after PD showing that inflammatory markers such as CRP may predict the risk for POPF." @default.
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- W3209505993 date "2021-01-01" @default.
- W3209505993 modified "2023-09-27" @default.
- W3209505993 title "Risk Factors for Postoperative Pancreatic Fistula after Pancreaticoduodenectomy - Preliminary Results of a Single Center Prospective Study" @default.
- W3209505993 doi "https://doi.org/10.1016/j.hpb.2021.08.921" @default.
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