Matches in SemOpenAlex for { <https://semopenalex.org/work/W3209526677> ?p ?o ?g. }
- W3209526677 endingPage "102869" @default.
- W3209526677 startingPage "102869" @default.
- W3209526677 abstract "The aim of this work was to develop a transdermal gel formulation for enhanced delivery of candesartan. The in vitro skin permeation of the drug was examined using modified Franz type diffusion cells and epidermal membrane, taken from full thickness hairless mouse skin. Initially, a full 24 factorial design was employed, in order to estimate the effects and interactions of the following factors: the chemical form of the Active Pharmaceutical Ingredient (API), the concentration of triethanolamine (TEtA), the concentration of 1,8-cineole and the type of the vehicle's co-solvent, on the in vitro skin permeation. The experimental design revealed the optimum formulation consisting of candesartan, 5% TEtA, 10% 1,8-cineole and glycerol formal, which provided an increased flux, approximately two hundred times higher than the control formulation. Furthermore, NMR and mass spectrometry demonstrated the ion pair formation between TEtA and candesartan as an effective strategy for significantly improving its in vitro skin permeation." @default.
- W3209526677 created "2021-11-08" @default.
- W3209526677 creator A5002624570 @default.
- W3209526677 creator A5008282175 @default.
- W3209526677 creator A5030929138 @default.
- W3209526677 creator A5043966827 @default.
- W3209526677 creator A5051929815 @default.
- W3209526677 creator A5068439544 @default.
- W3209526677 date "2022-01-01" @default.
- W3209526677 modified "2023-10-14" @default.
- W3209526677 title "Effect of triethanolamine as counter ion on the transdermal permeation of candesartan" @default.
- W3209526677 cites W1976208663 @default.
- W3209526677 cites W1980506388 @default.
- W3209526677 cites W1982901783 @default.
- W3209526677 cites W1989220971 @default.
- W3209526677 cites W1993219070 @default.
- W3209526677 cites W1994237394 @default.
- W3209526677 cites W1995441472 @default.
- W3209526677 cites W2013797386 @default.
- W3209526677 cites W2016581182 @default.
- W3209526677 cites W2023071966 @default.
- W3209526677 cites W2024557497 @default.
- W3209526677 cites W2028670147 @default.
- W3209526677 cites W2038784648 @default.
- W3209526677 cites W2041244310 @default.
- W3209526677 cites W2044806301 @default.
- W3209526677 cites W2045620021 @default.
- W3209526677 cites W2052430500 @default.
- W3209526677 cites W2057408279 @default.
- W3209526677 cites W2063067967 @default.
- W3209526677 cites W2063472880 @default.
- W3209526677 cites W2069057046 @default.
- W3209526677 cites W2073244528 @default.
- W3209526677 cites W2080576642 @default.
- W3209526677 cites W2081159973 @default.
- W3209526677 cites W2088555693 @default.
- W3209526677 cites W2097510064 @default.
- W3209526677 cites W2102250394 @default.
- W3209526677 cites W2109744806 @default.
- W3209526677 cites W2112448201 @default.
- W3209526677 cites W2118587393 @default.
- W3209526677 cites W2141331305 @default.
- W3209526677 cites W2168292600 @default.
- W3209526677 cites W2566463473 @default.
- W3209526677 cites W2901137783 @default.
- W3209526677 cites W3192973584 @default.
- W3209526677 cites W4210957996 @default.
- W3209526677 cites W4231446881 @default.
- W3209526677 cites W4252810012 @default.
- W3209526677 cites W71151985 @default.
- W3209526677 doi "https://doi.org/10.1016/j.jddst.2021.102869" @default.
- W3209526677 hasPublicationYear "2022" @default.
- W3209526677 type Work @default.
- W3209526677 sameAs 3209526677 @default.
- W3209526677 citedByCount "0" @default.
- W3209526677 crossrefType "journal-article" @default.
- W3209526677 hasAuthorship W3209526677A5002624570 @default.
- W3209526677 hasAuthorship W3209526677A5008282175 @default.
- W3209526677 hasAuthorship W3209526677A5030929138 @default.
- W3209526677 hasAuthorship W3209526677A5043966827 @default.
- W3209526677 hasAuthorship W3209526677A5051929815 @default.
- W3209526677 hasAuthorship W3209526677A5068439544 @default.
- W3209526677 hasConcept C113196181 @default.
- W3209526677 hasConcept C170493617 @default.
- W3209526677 hasConcept C185592680 @default.
- W3209526677 hasConcept C192562407 @default.
- W3209526677 hasConcept C205679159 @default.
- W3209526677 hasConcept C2775897365 @default.
- W3209526677 hasConcept C2780036600 @default.
- W3209526677 hasConcept C2908929049 @default.
- W3209526677 hasConcept C41625074 @default.
- W3209526677 hasConcept C43617362 @default.
- W3209526677 hasConcept C45904493 @default.
- W3209526677 hasConcept C50670333 @default.
- W3209526677 hasConcept C55493867 @default.
- W3209526677 hasConcept C71924100 @default.
- W3209526677 hasConcept C98274493 @default.
- W3209526677 hasConceptScore W3209526677C113196181 @default.
- W3209526677 hasConceptScore W3209526677C170493617 @default.
- W3209526677 hasConceptScore W3209526677C185592680 @default.
- W3209526677 hasConceptScore W3209526677C192562407 @default.
- W3209526677 hasConceptScore W3209526677C205679159 @default.
- W3209526677 hasConceptScore W3209526677C2775897365 @default.
- W3209526677 hasConceptScore W3209526677C2780036600 @default.
- W3209526677 hasConceptScore W3209526677C2908929049 @default.
- W3209526677 hasConceptScore W3209526677C41625074 @default.
- W3209526677 hasConceptScore W3209526677C43617362 @default.
- W3209526677 hasConceptScore W3209526677C45904493 @default.
- W3209526677 hasConceptScore W3209526677C50670333 @default.
- W3209526677 hasConceptScore W3209526677C55493867 @default.
- W3209526677 hasConceptScore W3209526677C71924100 @default.
- W3209526677 hasConceptScore W3209526677C98274493 @default.
- W3209526677 hasLocation W32095266771 @default.
- W3209526677 hasOpenAccess W3209526677 @default.
- W3209526677 hasPrimaryLocation W32095266771 @default.
- W3209526677 hasRelatedWork W1991046203 @default.
- W3209526677 hasRelatedWork W2038784648 @default.
- W3209526677 hasRelatedWork W2075718401 @default.