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- W3209529515 endingPage "63" @default.
- W3209529515 startingPage "42" @default.
- W3209529515 abstract "Magnesium alloys are considered the most suitable absorbable metals for bone fracture fixation implants. The main challenge in absorbable magnesium alloys is their high corrosion/degradation rate that needs to be controlled. Various coatings have been applied to magnesium alloys to slow down their corrosion rates to match their corrosion rate to the regeneration rate of the bone fracture. In this review, a bioactive coating is proposed to slow down the corrosion rate of magnesium alloys and accelerate the bone fracture healing process. The main aim of the bioactive coatings is to enhance the direct attachment of living tissues and thereby facilitate osteoconduction. Hydroxyapatite, collagen type I, recombinant human bone morphogenetic proteins 2, simvastatin, zoledronate, and strontium are six bioactive agents that show high potential for developing a bioactive coating system for high-performance absorbable magnesium bone implants. In addition to coating, the substrate itself can be made bioactive by alloying magnesium with calcium, zinc, copper, and manganese that were found to promote bone regeneration." @default.
- W3209529515 created "2021-11-08" @default.
- W3209529515 creator A5008212381 @default.
- W3209529515 creator A5044458202 @default.
- W3209529515 creator A5044886653 @default.
- W3209529515 creator A5046880733 @default.
- W3209529515 creator A5053938069 @default.
- W3209529515 creator A5061102998 @default.
- W3209529515 creator A5088177806 @default.
- W3209529515 date "2022-06-01" @default.
- W3209529515 modified "2023-09-30" @default.
- W3209529515 title "Potential bioactive coating system for high-performance absorbable magnesium bone implants" @default.
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