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- W3209664564 abstract "Growth traits are of great importance for poultry breeding and production and have been the topic of extensive investigation, with many quantitative trait loci (QTL) detected. However, due to their complex genetic background, few causative genes have been confirmed and the underlying molecular mechanisms remain unclear, thus limiting our understanding of QTL and their potential use for the genetic improvement of poultry. Therefore, deciphering the genetic architecture is a promising avenue for optimising genomic prediction strategies and exploiting genomic information for commercial breeding. The objectives of this study were to: (1) conduct a genome-wide association study to identify key genetic factors and explore the polygenicity of chicken growth traits; (2) investigate the efficiency of genomic prediction in broilers; and (3) evaluate genomic predictions that harness genomic features.We identified five significant QTL, including one on chromosome 4 with major effects and four on chromosomes 1, 2, 17, and 27 with minor effects, accounting for 14.5 to 34.1% and 0.2 to 2.6% of the genomic additive genetic variance, respectively, and 23.3 to 46.7% and 0.6 to 4.5% of the observed predictive accuracy of breeding values, respectively. Further analysis showed that the QTL with minor effects collectively had a considerable influence, reflecting the polygenicity of the genetic background. The accuracy of genomic best linear unbiased predictions (BLUP) was improved by 22.0 to 70.3% compared to that of the conventional pedigree-based BLUP model. The genomic feature BLUP model further improved the observed prediction accuracy by 13.8 to 15.2% compared to the genomic BLUP model.A major QTL and four minor QTL were identified for growth traits; the remaining variance was due to QTL effects that were too small to be detected. The genomic BLUP and genomic feature BLUP models yielded considerably higher prediction accuracy compared to the pedigree-based BLUP model. This study revealed the polygenicity of growth traits in yellow-plumage chickens and demonstrated that the predictive ability can be greatly improved by using genomic information and related features." @default.
- W3209664564 created "2021-11-08" @default.
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- W3209664564 date "2021-10-27" @default.
- W3209664564 modified "2023-10-13" @default.
- W3209664564 title "Genome‑wide association study and genomic prediction for growth traits in yellow-plumage chicken using genotyping-by-sequencing" @default.
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- W3209664564 cites W1825860353 @default.
- W3209664564 cites W1839107343 @default.
- W3209664564 cites W1928998639 @default.
- W3209664564 cites W1956441033 @default.
- W3209664564 cites W1962321979 @default.
- W3209664564 cites W1965621126 @default.
- W3209664564 cites W1972216668 @default.
- W3209664564 cites W1972596659 @default.
- W3209664564 cites W1977950286 @default.
- W3209664564 cites W2020320027 @default.
- W3209664564 cites W2023673366 @default.
- W3209664564 cites W2028735580 @default.
- W3209664564 cites W2033151532 @default.
- W3209664564 cites W2035162791 @default.
- W3209664564 cites W2038260948 @default.
- W3209664564 cites W2060293383 @default.
- W3209664564 cites W2063090075 @default.
- W3209664564 cites W2077668635 @default.
- W3209664564 cites W2077763475 @default.
- W3209664564 cites W2087761312 @default.
- W3209664564 cites W2094198395 @default.
- W3209664564 cites W2095987942 @default.
- W3209664564 cites W2096128561 @default.
- W3209664564 cites W2108583185 @default.
- W3209664564 cites W2110798717 @default.
- W3209664564 cites W2142727510 @default.
- W3209664564 cites W2156215519 @default.
- W3209664564 cites W2160607966 @default.
- W3209664564 cites W2161633633 @default.
- W3209664564 cites W2184774706 @default.
- W3209664564 cites W2190960123 @default.
- W3209664564 cites W2254979106 @default.
- W3209664564 cites W2316360588 @default.
- W3209664564 cites W2334453152 @default.
- W3209664564 cites W2377407741 @default.
- W3209664564 cites W2401569012 @default.
- W3209664564 cites W2491736610 @default.
- W3209664564 cites W2528815158 @default.
- W3209664564 cites W2533368445 @default.
- W3209664564 cites W2580517199 @default.
- W3209664564 cites W2583919829 @default.
- W3209664564 cites W2600955197 @default.
- W3209664564 cites W2606560121 @default.
- W3209664564 cites W2623348960 @default.
- W3209664564 cites W2626606138 @default.
- W3209664564 cites W2738510634 @default.
- W3209664564 cites W2765094284 @default.
- W3209664564 cites W2767520269 @default.
- W3209664564 cites W2801933709 @default.
- W3209664564 cites W2807724764 @default.
- W3209664564 cites W2810562347 @default.
- W3209664564 cites W2885778610 @default.
- W3209664564 cites W2886378237 @default.
- W3209664564 cites W2899867539 @default.
- W3209664564 cites W2912890533 @default.
- W3209664564 cites W2924036988 @default.
- W3209664564 cites W2931834045 @default.
- W3209664564 cites W2952113787 @default.
- W3209664564 cites W2952218813 @default.
- W3209664564 cites W2955612853 @default.
- W3209664564 cites W2968458064 @default.
- W3209664564 cites W2973029867 @default.
- W3209664564 cites W2981098318 @default.
- W3209664564 cites W2981346658 @default.
- W3209664564 cites W2991875949 @default.
- W3209664564 cites W3019408181 @default.
- W3209664564 cites W3042318275 @default.
- W3209664564 cites W3081879876 @default.
- W3209664564 cites W3108090783 @default.
- W3209664564 cites W4292239814 @default.
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- W3209664564 doi "https://doi.org/10.1186/s12711-021-00672-9" @default.
- W3209664564 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/8555081" @default.
- W3209664564 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/34706641" @default.
- W3209664564 hasPublicationYear "2021" @default.
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