FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W3209718855> ?p ?o ?g. }

• W3209718855 abstract "Several existing scoring systems predict survival of patients with colorectal liver metastases. Many lack validation, rely on old clinical data, and have been found to be less accurate since the introduction of chemotherapy. This study aimed to construct and validate a clinically relevant preoperative prognostic model for patients with colorectal liver metastases.A predictive model with data available before surgery was developed. Survival was analysed by Cox regression analysis, and the quality of the model was assessed using discrimination and calibration. The model was validated using multifold cross-validation.The model included 1212 consecutive patients who underwent liver resection for colorectal liver metastases between 2005 and 2015. Prognostic factors for survival included advanced age, raised C-reactive protein level, hypoalbuminaemia, extended liver resection, larger number of metastases, and midgut origin of the primary tumour. A Composite Score was developed based on the prognostic variables. Patients were classified into those at low, medium, and high risk. Survival differences between the groups were significant; median overall survival was 87.4 months in the low-risk group, 50.1 months in the medium-risk group, and 22.6 months in the high-risk group. The discriminative performance, assessed by the concordance index, was 0.71, 0.67, and 0.67 respectively at 1, 3, and 5 years. Calibration, assessed graphically, was close to perfect. A multifold cross-validation of the model confirmed its internal validity (C-index 0.63 versus 0.62).The Composite Score categorizes patients into risk strata, and may help identify patients who have a poor prognosis, for whom surgery is questionable." @default.
• W3209718855 created "2021-11-08" @default.
• W3209718855 creator A5005453977 @default.
• W3209718855 creator A5017455729 @default.
• W3209718855 creator A5029622754 @default.
• W3209718855 creator A5081653831 @default.
• W3209718855 date "2021-09-06" @default.
• W3209718855 modified "2023-10-07" @default.
• W3209718855 title "Composite Score: prognostic tool to predict survival in patients undergoing surgery for colorectal liver metastases" @default.
• W3209718855 cites W1765193236 @default.
• W3209718855 cites W1774948393 @default.
• W3209718855 cites W1963697247 @default.
• W3209718855 cites W1971211622 @default.
• W3209718855 cites W1975108860 @default.
• W3209718855 cites W1985299015 @default.
• W3209718855 cites W1988375742 @default.
• W3209718855 cites W1988902102 @default.
• W3209718855 cites W1989175303 @default.
• W3209718855 cites W2009432182 @default.
• W3209718855 cites W2021031183 @default.
• W3209718855 cites W2035454562 @default.
• W3209718855 cites W2051411536 @default.
• W3209718855 cites W2059975503 @default.
• W3209718855 cites W2065974896 @default.
• W3209718855 cites W2073513821 @default.
• W3209718855 cites W2074811887 @default.
• W3209718855 cites W2077428590 @default.
• W3209718855 cites W2080229397 @default.
• W3209718855 cites W2084470612 @default.
• W3209718855 cites W2085186223 @default.
• W3209718855 cites W2088417780 @default.
• W3209718855 cites W2095201384 @default.
• W3209718855 cites W2098370829 @default.
• W3209718855 cites W2100741073 @default.
• W3209718855 cites W2110682589 @default.
• W3209718855 cites W2119910794 @default.
• W3209718855 cites W2125557181 @default.
• W3209718855 cites W2134431449 @default.
• W3209718855 cites W2136085913 @default.
• W3209718855 cites W2138235363 @default.
• W3209718855 cites W2138575316 @default.
• W3209718855 cites W2144326782 @default.
• W3209718855 cites W2154064843 @default.
• W3209718855 cites W2157716751 @default.
• W3209718855 cites W2157825442 @default.
• W3209718855 cites W2159235877 @default.
• W3209718855 cites W2200286273 @default.
• W3209718855 cites W2297716127 @default.
• W3209718855 cites W2470575266 @default.
• W3209718855 cites W2527832410 @default.
• W3209718855 cites W2529942642 @default.
• W3209718855 cites W2536071775 @default.
• W3209718855 cites W2558788971 @default.
• W3209718855 cites W2617021687 @default.
• W3209718855 cites W2617980636 @default.
• W3209718855 cites W2801227536 @default.
• W3209718855 cites W2906409409 @default.
• W3209718855 cites W2975954696 @default.
• W3209718855 cites W3082631516 @default.
• W3209718855 cites W3103760322 @default.
• W3209718855 cites W4238418436 @default.
• W3209718855 doi "https://doi.org/10.1093/bjsopen/zrab104" @default.
• W3209718855 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/8545612" @default.
• W3209718855 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/34697642" @default.
• W3209718855 hasPublicationYear "2021" @default.
• W3209718855 type Work @default.
• W3209718855 sameAs 3209718855 @default.
• W3209718855 citedByCount "4" @default.
• W3209718855 countsByYear W32097188552022 @default.
• W3209718855 countsByYear W32097188552023 @default.
• W3209718855 crossrefType "journal-article" @default.
• W3209718855 hasAuthorship W3209718855A5005453977 @default.
• W3209718855 hasAuthorship W3209718855A5017455729 @default.
• W3209718855 hasAuthorship W3209718855A5029622754 @default.
• W3209718855 hasAuthorship W3209718855A5081653831 @default.
• W3209718855 hasBestOaLocation W32097188551 @default.
• W3209718855 hasConcept C121608353 @default.
• W3209718855 hasConcept C126322002 @default.
• W3209718855 hasConcept C141071460 @default.
• W3209718855 hasConcept C143998085 @default.
• W3209718855 hasConcept C160798450 @default.
• W3209718855 hasConcept C50382708 @default.
• W3209718855 hasConcept C526805850 @default.
• W3209718855 hasConcept C71924100 @default.
• W3209718855 hasConceptScore W3209718855C121608353 @default.
• W3209718855 hasConceptScore W3209718855C126322002 @default.
• W3209718855 hasConceptScore W3209718855C141071460 @default.
• W3209718855 hasConceptScore W3209718855C143998085 @default.
• W3209718855 hasConceptScore W3209718855C160798450 @default.
• W3209718855 hasConceptScore W3209718855C50382708 @default.
• W3209718855 hasConceptScore W3209718855C526805850 @default.
• W3209718855 hasConceptScore W3209718855C71924100 @default.
• W3209718855 hasIssue "5" @default.
• W3209718855 hasLocation W32097188551 @default.
• W3209718855 hasLocation W32097188552 @default.
• W3209718855 hasLocation W32097188553 @default.
• W3209718855 hasLocation W32097188554 @default.
• W3209718855 hasLocation W32097188555 @default.
• W3209718855 hasOpenAccess W3209718855 @default.
• W3209718855 hasPrimaryLocation W32097188551 @default.

• next